Abstract:
:Cholecystokinin-octapeptide-like-immunoreactivity (CCK-8-LI) is demonstrable by the indirect immunofluorescent technique in cerebral cortical neurons cultured from fetal rats. Prominent and widespread staining is seen in widely ramifying cellular processes throughout the cultures. Staining in neuronal cell bodies is enhanced by treatment of the cultures with colchicine prior to fixation and can be seen to extend from the perikaryal region into dendrites and axonal processes. While several morphological types of neurons contain CCK-8-LI, there is a relative preponderance of small and moderate-sized bipolar and, to a lesser extent, multipolar neurons. These findings are in concordance with the findings of several investigators in studies of brain sections. The further finding of frequent groupings of CCK-8 neurons is noted and discussed.
journal_name
Brain Resjournal_title
Brain researchauthors
Delfs JR,Zhu CH,Dichter MAdoi
10.1016/0006-8993(84)91456-2subject
Has Abstractpub_date
1984-02-13 00:00:00pages
93-9issue
1eissn
0006-8993issn
1872-6240pii
0006-8993(84)91456-2journal_volume
293pub_type
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