Peripheral hyperalgesia in experimental neuropathy: exacerbation by neuropeptide Y.

abstract：:Presumptive neurons, immature neurons and degenerating structures were found in the intermediate and deep layers of the superior colliculus of normal cats over the age range 7-45 days postnatal. Electron microscopical analysis revealed these structures to be unexpectedly frequent in the early postnatal period. There w...

journal_title：Brain research

authors： Warton SS,Jones DG

更新日期：1984-05-01 00:00:00

abstract：:Overactivation of poly (ADP-ribose) polymerase-1 (PARP-1) in response to DNA damage is considered to play a crucial role in the development of post-ischemic neuronal injury, such as ischemic stroke. The present study was undertaken to clarify the beneficial effects of MP-124, a novel PARP-1 inhibitor, on neurological ...

journal_title：Brain research

authors： Matsuura S,Egi Y,Yuki S,Horikawa T,Satoh H,Akira T

更新日期：2011-09-02 00:00:00

abstract：:Alteration of blood-brain barrier (BBB) permeability by 2450 MHz CW microwaves was assessed semi-quantitatively after intravenous injection of horseradish peroxidase (HRP) and exposure of conscious, unrestrained rats to incident power densities of 0, 20 or 65 mW/cm2 for 30, 90 or 180 min. Additional rats were exposed ...

journal_title：Brain research

authors： Williams WM,Del Cerro M,Michaelson SM

更新日期：1984-05-01 00:00:00

abstract：:Blockade of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptors with 6-nitro-7-sulfamoyl-benzo-[f]quinoxaline-2,3(1H,4H)-dione (NBQX) activates tuberoinfundibular (TIDA) and periventricular-hypophysial dopaminergic (PHDA) neurons suggesting that these neurons are tonically inhibited by endogenous...

journal_title：Brain research

authors： Wagner EJ,Moore KE,Lookingland KJ

更新日期：1994-10-17 00:00:00

abstract：:The magnetoencephalographic signal was collected in a visually guided response-finger selection GO/NOGO task. The minimum norm distributed source analysis identified the sources in bilateral superior parietal lobules (SPL), with stronger activity for contralateral finger movement. Our results suggest that the human SP...

journal_title：Brain research

authors： Shibata T,Ioannides AA

更新日期：2001-04-06 00:00:00

abstract：:Bombesin-like immunoreactivity occurs in a dense network of nerve fibres in the rat coeliac-superior mesenteric ganglion. No bombesin immunoreactive cell bodies have been observed in this ganglion. An origin outside the ganglion was therefore assumed for the bombesin immunoreactive fibres. Ligation of the mesenteric n...

journal_title：Brain research

authors： Schultzberg M,Dalsgaard CJ

更新日期：1983-06-13 00:00:00

abstract：:Veratridine-induced depolarization caused a large increase in Ca uptake in the rat hippocampal slice (30.2 vs. 9.0 nM/mg dry weight). This uptake was reduced to 18.4 nM/mg when veratridine was combined with anoxia. When compared with veratridine exposure alone, the combination of anoxia and veratridine increased intra...

journal_title：Brain research

authors： Kass IS,Abramowicz AE,Cottrell JE,Amorim P,Chambers G

更新日期：1994-01-07 00:00:00

abstract：:This study examined the involvement of N-methyl-D-aspartate receptors (NMDARs) in experience-dependent synaptic plasticity. Rats chronically received an NMDA receptor antagonist (AP5) or saline (SAL) and were exposed to individual cages (IC) or environmental enrichment (EC). AP5 impaired measures of hippocampal-depend...

journal_title：Brain research

authors： Foster TC,Fugger HN,Cunningham SG

更新日期：2000-07-14 00:00:00

abstract：:In the urethane-anesthetized rat both electrical stimulation (20 microA, 0.2 ms, 30 s) through micropipettes and glutamate injections (0.1 M, 100 nl) within an area including the dorsal lateral parabrachial nucleus, the adjacent central lateral parabrachial nucleus, the external lateral parabrachial nucleus, the Kölli...

journal_title：Brain research

authors： Ward DG

更新日期：1988-10-18 00:00:00

abstract：:For the evaluation of glutamatergic and GABAergic transmission during seizures, rat hippocampal CA1 and CA3 areas were separately assessed by brain microdialysis, and extracelluar glutamate and GABA were measured through the course of the seizures after a systemic administration of kainic acid (KA). The generalized co...

journal_title：Brain research

authors： Ding R,Asada H,Obata K

更新日期：1998-07-27 00:00:00

abstract：:The use of the fluorescence retrograde double-labeling method has revealed that striatal neurons projecting to the globus pallidus in the squirrel monkey are mainly confined to the putamen whereas those projecting to the substantia nigra occur mostly in the caudate nucleus. Only about 10% of the striatal neurons were ...

journal_title：Brain research

authors： Parent A,Bouchard C,Smith Y

更新日期：1984-06-15 00:00:00

abstract：:The search for the neural substrate of a state of consciousness has led to the expectation that there may be neurons which discharge tonically and rhythmically during that state alone. We have now recorded in the cat the first evidence of neurons whose rhythmic discharge is consistent with the hypothesis of a tonicall...

journal_title：Brain research

authors： Netick A,Orem J,Dement W

更新日期：1977-01-21 00:00:00

abstract：:Although there are several reports on the alteration of intracellular signal transduction during heat shock in somatic cells, the long term effects of heat shock on neuronal cells remain unknown. In this report, we investigated cyclic AMP (cAMP) accumulation and the expression of heat shock proteins following heat sho...

journal_title：Brain research

authors： Zensho H,Nishida A,Shimizu M,Uchitomi Y,Yamawaki S

更新日期：1998-04-20 00:00:00

abstract：:Central catecholamine alterations associated with immune activity are similar to those seen following stressor exposure. Inasmuch as aged animals exhibit more pronounced stressor-provoked alterations of central amines relative to younger animals, it was of interest to determine whether immune challenge would similarly...

journal_title：Brain research

authors： Shanks N,Francis D,Zalcman S,Meaney MJ,Anisman H

更新日期：1994-12-12 00:00:00

abstract：:Administration of methyl palmoxirate (MP), an inhibitor of fatty acid oxidation, stimulates eating behavior in rats. Fos immunohistochemistry was used to determine neural pathways that may play a role in the eating response to MP. The number of cells showing Fos-like immunoreactivity (Fos-li) was quantified by compute...

journal_title：Brain research

authors： Horn CC,Friedman MI

更新日期：1998-01-19 00:00:00

abstract：:The occurrence of hypoxia-ischemia (HI) during early fetal or neonatal stages of an individual leads to the damaging of immature neurons resulting in behavioral and psychological dysfunctions, such as motor or learning disabilities, cerebral palsy, epilepsy or even death. No effective treatment is currently available ...

journal_title：Brain research

authors： Calvert JW,Yin W,Patel M,Badr A,Mychaskiw G,Parent AD,Zhang JH

更新日期：2002-09-27 00:00:00

abstract：:Trials of neuroprotection in ischemic stroke mainly concern gray matter protection, with little information on white matter damage. Olfactory ensheathing cells (OECs) are capable of providing continuous neurotrophic factor and of promoting growth and remyelination of damaged axons. We evaluated OECs for the repair of ...

journal_title：Brain research

authors： Shi X,Kang Y,Hu Q,Chen C,Yang L,Wang K,Chen L,Huang H,Zhou C

更新日期：2010-03-04 00:00:00

abstract：:The ontogenesis of chromogranins A and B and catecholamines was investigated for rat adrenal medulla. The chromogranins, the major secretory peptides of chromaffin granules, were characterized by one- and two-dimensional immunoblotting. Chromogranin B appeared identical in fetal and postnatal adrenals. On the other ha...

journal_title：Brain research

authors： Schober M,Fischer-Colbrie R,Winkler H

更新日期：1989-01-23 00:00:00

abstract：:Intracisternal (i.c.) administration of the glutamate-receptor antagonist kynurenate to halothane-anesthetized rats (paralyzed, ventilated) produced an initial hypertension associated with an increase in lumbar sympathetic nerve discharge. Kynurenate (i.c.) blocked or greatly reduced all sympathetic reflexes investiga...

journal_title：Brain research

authors： Sun MK,Hackett JT,Guyenet PG

更新日期：1988-01-12 00:00:00

abstract：:In recent years microvillar cells (MVC) have been identified in the olfactory epithelium of numerous species, including rodents, canines, and primates. However, there is no consensus on the morphologic or histochemical features of this cell, nor is the function of these cells currently known. Previous studies have exa...

journal_title：Brain research

authors： Miller ML,Andringa A,Evans JE,Hastings L

更新日期：1995-01-09 00:00:00

abstract：:Chemical (C) kindling by means of repeated spaced injections into the amygdala (AM) of a subconvulsive dose of L-glutamate and L-aspartate combined in a molar ratio of 1:3. (Glu/Asp) produced progressive seizure development culminating in generalized convulsion strikingly similar to electrically kindled Stage 5 seizur...

journal_title：Brain research

authors： Mori N,Wada JA

更新日期：1987-11-03 00:00:00

abstract：:Reduced neuronal plasticity in the striatum, hippocampus, and neocortex is a common feature of transgenic mouse models of Huntington's disease (HD). Doublecortin (DCX) and polysialylated neural cell adhesion molecule (PSA-NCAM) are associated with structural plasticity in the adult mammalian brain, are markers of newl...

journal_title：Brain research

authors： Lazic SE,Goodman AO,Grote HE,Blakemore C,Morton AJ,Hannan AJ,van Dellen A,Barker RA

更新日期：2007-06-02 00:00:00

abstract：:Computer-assisted morphometrics were used to characterize mature somatodendritic architecture in Golgi-stained neurons of the entopeduncular nucleus (EN) of the adult cat. Only one form of adult EN neuron was apparent and characterized by common features including: relatively large conical somata, long aspiny and mode...

journal_title：Brain research

authors： Dvergsten CL,Hull CD,Levine MS,Adinolfi AM,Fisher RS,Buchwald NA

更新日期：1986-06-11 00:00:00

abstract：:Striatal D2 dopamine receptor concentrations were shown to decrease 30-35% during the lifespan of Wistar rats as assessed both radiochemically and autoradiographically. Binding densities and degree of age-change varied within the striatum; the latter ranging from 17 to 44% in 4 different regions. Overall neuronal loss...

journal_title：Brain research

authors： Han Z,Kuyatt BL,Kochman KA,DeSouza EB,Roth GS

更新日期：1989-10-02 00:00:00

abstract：:Chick pineal cells contain a circadian oscillator that derives rhythmic synthesis and secretion of melatonin even in dispersed cell culture. Here, we demonstrate that the mRNA encoding tryptophan hydroxylase (TPH), the first enzyme in the melatonin synthetic pathway, is expressed rhythmically under the control of the ...

journal_title：Brain research

authors： Green CB,Besharse JC,Zatz M

更新日期：1996-10-28 00:00:00

abstract：:Neonatal hypoxia-ischemia (HI) has been extensively studied in a rat model characterized by unilateral brain damage (Rice-Vannucci Model). However, as well as in humans, each rat brain hemisphere is distinctly involved in cognitive functions, as for example retrieval of emotionally based memory, and neurochemical asym...

journal_title：Brain research

authors： Arteni NS,Salgueiro J,Torres I,Achaval M,Netto CA

更新日期：2003-05-30 00:00:00

abstract：:The function of the phosphoinositide signal transduction system and the levels of heterotrimeric G-protein alpha-subunits were examined in postmortem prefrontal cortex regions (8/9) and region (10) from suicide victims with major depression and matched control subjects without psychiatric illness. The hydrolysis of [3...

journal_title：Brain research

authors： Pacheco MA,Stockmeier C,Meltzer HY,Overholser JC,Dilley GE,Jope RS

更新日期：1996-06-03 00:00:00

abstract：:The mRNA level of the 17-kDa protein neurogranin (NG), a postsynaptic substrate of the protein kinase C, has previously been found to be decreased in rat forebrain after 24-h sleep deprivation (SD). To investigate the functional significance of this finding in various forebrain regions, the effect of 24-h SD on the mR...

journal_title：Brain research

authors： Neuner-Jehle M,Rhyner TA,Borbély AA

更新日期：1995-07-10 00:00:00

abstract：:Somatosensory evoked potentials (SEP) recorded from humans were elicited by a cutaneous shock to the index finger or with a ramp displacement of the finger that stretched the first dorsal interosseous muscle. A somatosensory stimulus was presented while a subject maintained a steady posture of the metacarpophalangeal ...

journal_title：Brain research

authors： Dimitrov B,Hallett M,Sanes JN

更新日期：1989-09-04 00:00:00

abstract：:Iontophoretic application of carbachol caused excitation of CA1 neurones and decreased the amplitude of antidromic CA1 population spikes recorded extracellularly. Adenosine, adenosine triphosphate (ATP) and the purine analogues N-ethylcarboxamide adenosine (NECA) and R- and S-phenylisopropyladenosine (PIA) reduced the...

journal_title：Brain research

authors： Brooks PA,Stone TW

更新日期：1988-08-16 00:00:00