Abstract：
:The mismatch negativity is an electrophysiological marker of auditory change detection in the event-related brain potential and has been proposed to reflect an automatic comparison process between an incoming stimulus and the representation of prior items in a sequence. There is evidence for two main functional subcomponents comprising the MMN, generated by temporal and frontal brain areas, respectively. Using data obtained in an MMN paradigm, we performed time-frequency analysis to reveal the changes in oscillatory neural activity in the theta band. The results suggest that the frontal component of the MMN is brought about by an increase in theta power for the deviant trials and, possibly, by an additional contribution of theta phase alignment. By contrast, the temporal component of the MMN, best seen in recordings from mastoid electrodes, is generated by phase resetting of theta rhythm with no concomitant power modulation. Thus, frontal and temporal MMN components do not only differ with regard to their functional significance but also appear to be generated by distinct neurophysiological mechanisms.
journal_name
Brain Resjournal_title
Brain researchauthors
Fuentemilla L,Marco-Pallarés J,Münte TF,Grau Cdoi
10.1016/j.brainres.2007.07.079subject
Has Abstractpub_date
2008-07-18 00:00:00pages
93-101eissn
0006-8993issn
1872-6240pii
S0006-8993(07)01788-Xjournal_volume
1220pub_type
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