Cerebral involvement in dehydration-induced natriuresis.

abstract：:Autoradiographic analysis of [(35)S]GTPgammaS binding was used to investigate functional activation of dopamine receptors in rat striatum. Dopamine-stimulated [(35)S]GTPgammaS binding was observed with a maximal increase of 38% over basal activity. A similar stimulatory response was obtained with the D(2) agonist quin...

journal_title：Brain research

authors： He L,Di Monte DA,Langston JW,Quik M

更新日期：2000-12-01 00:00:00

abstract：:The solubilized rat central nervous system (hypothalamic) nicotinic cholinergic receptor and the Torpedo nicotinic cholinergic receptors are immunologically similar and show greater than 60% immunologic cross-reactivity using a double-antibody technique. Antibodies to the Electrophorus and Torpedo receptors also decre...

journal_title：Brain research

authors： Block GA,Billiar RB

更新日期：1979-12-14 00:00:00

abstract：:Recent developments in the understanding of the neurophysiological mechanisms underlying electroencephalographic (EEG) slow waves and sleep spindles imply an inverse relationship between these two EEG activities. The interrelationship between slow wave activity (0.75-4.5 Hz) and sleep-spindle activity (12-15 Hz) in el...

journal_title：Brain research

authors： Dijk DJ,Hayes B,Czeisler CA

更新日期：1993-10-29 00:00:00

abstract：:Immunohistochemical and neuronal tracing methods were used in cats to determine which type of postganglionic sympathetic neuron is innervated by preganglionic neurons which contain corticotrophin releasing factor-like immunoreactivity (CRF-LI). Preganglionic neurons with CRF-LI have their cell bodies at two restricted...

journal_title：Brain research

authors： Shafton AD,Oldfield BJ,McAllen RM

更新日期：1992-12-25 00:00:00

abstract：:Recently, cerebral blood flow changes were re-discussed to contribute to tissue protection after preconditioning. In the present study, we demonstrate increased vessel diameters of the leptomeningeal anastomoses after hypoxic preconditioning by visualization of the brain angioarchitecture using the latex perfusion tec...

journal_title：Brain research

authors： Woitzik J,Hecht N,Schneider UC,Peña-Tapia PG,Vajkoczy P

更新日期：2006-10-18 00:00:00

abstract：:Acute and repeated exposure to cocaine induces long-lasting alterations in neural networks that underlie compulsive drug seeking and taking. Cocaine exposure triggers complex adaptations in the brain that are mediated by dynamic patterns of gene expression that are translated into enduring changes. Recently, epigeneti...

journal_title：Brain research

authors： Sadri-Vakili G

更新日期：2015-12-02 00:00:00

abstract：:Aging leads to a decrease in the number of neurons expressing vasopressin (VP) and vasoactive intestinal polypeptide (VIP) in the suprachiasmatic nucleus (SCN) of the rat. Similar results were observed following prolonged alcohol consumption and withdrawal. In the latter circumstances, the administration of nerve grow...

journal_title：Brain research

authors： Pereira PA,Cardoso A,Paula-Barbosa MM

更新日期：2005-06-28 00:00:00

abstract：:An object recognition task was used to determine if chronic restraint stress (6 h/day for 21 days) impairs non-spatial memory, since chronic restraint is known to impair spatial memory. In addition, food deprivation was tested as a possible modulating factor of any stress effect in this non-reward-dependent task. Foll...

journal_title：Brain research

authors： Beck KD,Luine VN

更新日期：1999-05-29 00:00:00

abstract：:Inhibitory GABAergic synaptic transmission in the mammalian hippocampus depends upon a hyperpolarized reversal potential for Cl(-) (ECl). To examine the regulation of ECl hyperpolarization we cultured hippocampal neurons for two weeks in either a low- or a high-concentration of KCl (2.6 or 18.7 mM, respectively). Neur...

journal_title：Brain research

authors： Balena T,Acton BA,Koval D,Woodin MA

更新日期：2008-04-18 00:00:00

abstract：:Prenatal exposure to opiates, which is invariably followed by postnatal withdrawal, can affect cognitive performance. To further characterize these effects, we examined radial 8-arm maze performance and expression of brain derived neurotrophic factor (BDNF) in male rats prenatally exposed to the opiate l-alpha-acetylm...

journal_title：Brain research

authors： Schrott LM,Franklin L',Serrano PA

更新日期：2008-03-10 00:00:00

abstract：:Previous reports from our laboratory have demonstrated that ethanol- and cannabinoid-induced ataxia is modulated by cerebellar adenosine A(1) receptor because intracerebellar (i.c.b.) adenosine A(1) agonists potentiated and A(1) antagonist attenuated ataxia by these psychoactive drugs. In this study, the novel approac...

journal_title：Brain research

authors： Dar MS,Mustafa SJ

更新日期：2002-12-06 00:00:00

abstract：:Continuing from earlier work which demonstrated the peripheral axonal regulation of Schwann cell myelination, this study has investigated the possibility that a peripheral axon can stimulate oligodendrocyte myelination. To test this hypothesis, regenerating PNS axons were allowed to interact with uncommitted oligodend...

journal_title：Brain research

authors： Weinberg EL,Spencer PS

更新日期：1979-02-23 00:00:00

abstract：:This work examines the age-related changes of the NO pathway in the central nervous system (CNS), analyzing nitric oxide synthase (NOS) isoform expression, the level of nitrotyrosine-modified proteins, and the NOS activity in the cerebral cortex, decorticated brain (basal ganglia, thalamus, hypothalamus, tegtum and te...

journal_title：Brain research

authors： Siles E,Martínez-Lara E,Cañuelo A,Sánchez M,Hernández R,López-Ramos JC,Del Moral ML,Esteban FJ,Blanco S,Pedrosa JA,Rodrigo J,Peinado MA

更新日期：2002-11-29 00:00:00

abstract：:The blood-brain barrier (BBB) prevents many drugs from entering the brain. Yet, conventional methods that open the BBB are technically demanding, poorly reversible, and can be associated with long-term adverse effects. In comparison, carbogen, which is introduced nearly a century ago as a treatment for psychiatric dis...

journal_title：Brain research

authors： Liao KH,Wei VC,Wang HL,Chen HY,Lai TW

更新日期：2019-10-01 00:00:00

abstract：:Lesions to the ventromedial hypothalamus (VMH) inhibit receptive sexual behavior in the whiptail lizard, Cnemidophorus uniparens, an all-female species. All lesions to the VMH that effectively abolished receptivity specifically damaged the dorsal lateral VMH, an area containing high concentrations of estrogen receptor...

journal_title：Brain research

authors： Kendrick AM,Rand MS,Crews D

更新日期：1995-05-22 00:00:00

abstract：:Intracranial pressure (ICP) was monitored to evaluate the therapeutic effect of hyperbaric oxygen (HBO(2)) treatment following traumatic brain injury (TBI). This subject is controversial. The aim of our study was to determine whether HBO(2) treatment has a therapeutic effect on ICP dynamics and survival following seve...

journal_title：Brain research

authors： Rogatsky GG,Kamenir Y,Mayevsky A

更新日期：2005-06-21 00:00:00

abstract：:Ultrastructural localization of a calcium-binding protein, calretinin, in the cerebellar cortex of the rat was examined with an immunoperoxidase method. The cerebellar lobule V was investigated in detail. In the molecular layer, calretinin immunoreactivity was found in parallel fibers and in their varicosities that fo...

journal_title：Brain research

authors： Arai R,Jacobowitz DM,Deura S

更新日期：1993-06-11 00:00:00

abstract：:Cognitive impairment is a prevalent non-motor feature of Parkinson's disease (PD) which can present even in early stages of the disease. Impairments in executive processing and working memory (WM) are common and have been attributed, in part, to abnormalities within the dorsolateral prefrontal cortex (DLPFC) and broad...

journal_title：Brain research

authors： Hill AT,McModie S,Fung W,Hoy KE,Chung SW,Bertram KL

更新日期：2020-01-01 00:00:00

abstract：:In barbiturate-anaesthetized spinal cats, antibody microprobes were used to examine immunoreactive substance P (irSP) release at sites within the spinal cord following cutaneous stimuli. A basal level of irSP release was detected in the region of the substantia gelatinosa of the lumbar spinal cord. No increase in this...

journal_title：Brain research

authors： Duggan AW,Hendry IA,Morton CR,Hutchison WD,Zhao ZQ

更新日期：1988-06-07 00:00:00

abstract：:Production of inflammatory cytokines, including tumor necrosis factor (TNF), interleukin-1 (IL-1) and interleukin-6 (IL-6), in the brain is increased in various diseases. To investigate the relationships between the effect of overproduction of IL-6 in the brain on central and peripheral production of TNF, IL-1 beta an...

journal_title：Brain research

authors： Di Santo E,Alonzi T,Fattori E,Poli V,Ciliberto G,Sironi M,Gnocchi P,Ricciardi-Castagnoli P,Ghezzi P

更新日期：1996-11-18 00:00:00

abstract：:Ginseng is one of most extensively used traditional oriental medicines worldwide with beneficial efficacy on cognitive function disorders. Pharmacological researches on its active ingredient--ginsenoside Rg1 revealed that it can improve learning and memory potentially via modulating neurotransmission in the central ne...

journal_title：Brain research

authors： Liu ZJ,Zhao M,Zhang Y,Xue JF,Chen NH

更新日期：2010-05-28 00:00:00

abstract：:The periaqueductal gray matter (PAG) has been implicated in a variety of different functions, including autonomic regulation. Chemical stimulation of the lateral PAG produces hypertension and tachycardia while activation of the ventrolateral PAG produces the opposite effect. While these effects are the result of alter...

journal_title：Brain research

authors： Farkas E,Jansen AS,Loewy AD

更新日期：1997-08-01 00:00:00

abstract：:The light and electron microscopic localization of leucine-enkephalin-containing terminals in the facial nucleus of the rat were investigated by means of the peroxidase-antiperoxidase (PAP) immunocytochemical technique. By light microscopy, leucine-enkephalin-like immunoreactive (LEI) terminals were unevenly distribut...

journal_title：Brain research

authors： Senba E,Tohyama M

更新日期：1983-09-05 00:00:00

abstract：:The localization of the receptor for apamin, a specific toxin for one class of sensitive Ca2+-dependent K+ channel, was studied in rat brain using an in vitro autoradiographic technique. Radiolabeled monoiodoapamin binds specifically to rat brain sections with a high affinity (Kd = 25 pM) to a single class of sites. A...

journal_title：Brain research

authors： Mourre C,Hugues M,Lazdunski M

更新日期：1986-09-24 00:00:00

abstract：:The distribution of agmatine (decarboxylated arginine) was mapped in the central nervous system (CNS) in the rat. Agmatine-like immunoreactivity was identified by light microscopy, exclusively in the cytoplasm of neuronal perikarya. Immunoreactive neurons were present in the cerebral cortex, predominantly within lamin...

journal_title：Brain research

authors： Otake K,Ruggiero DA,Regunathan S,Wang H,Milner TA,Reis DJ

更新日期：1998-03-16 00:00:00

abstract：:Recent evidence indicates that the superior colliculus (SC), in addition to its functions in sensory detection, also participates in controlling the generalized activation state of the forebrain, as measured by the electroencephalogram (EEG) or electrocorticogram (ECoG). The mechanisms by which the SC modulates forebr...

journal_title：Brain research

authors： Dringenberg HC,Vanderwolf CH,Noseworthy PA

更新日期：2003-02-21 00:00:00

abstract：:Focal axonal swellings are characteristic of a wide range of neuropathies. Three neuron-specific monoclonal antibodies have been used to identify focal axonal swellings in the normal developing rat cerebellar cortex. Between 7 and 15 days postnatal, swellings are a common feature of the granular layer and white matter...

journal_title：Brain research

authors： Gravel C,Leclerc N,Plioplys A,Hawkes RB

更新日期：1986-01-22 00:00:00

abstract：:Zinc-enriched (ZEN) neurons are distributed widely throughout the brain and spinal cord. Synaptic vesicle zinc in these neurons is thought to function as a neuromodulator upon its release into the synaptic cleft. Consistent with this possibility, zinc or zinc chelators can alter spatial learning, working memory, and n...

journal_title：Brain research

authors： Cole TB,Martyanova A,Palmiter RD

更新日期：2001-02-09 00:00:00

abstract：:The objective of this study was to assess the influence of Ca2+ influx on intracellular pH (pHi) of neocortical neurons in primary culture. Neurons were exposed to glutamate (100-500 microM) or KCl (50 mM), and pHi was recorded with microspectrofluorometric techniques. Additional experiments were carried out in which ...

journal_title：Brain research

authors： OuYang YB,Kristián T,Kristiánová V,Mellergård P,Siesjö BK

更新日期：1995-04-10 00:00:00

abstract：:There is evidence that acute exposure to kainic acid (KA) induces the release of endogenous ligands for opioid receptors and that mu-opioid agonists intensify KA-induced neurodegeneration. The aim of the present study was to investigate any acute toxic effects of KA upon mu-opioid receptors labelled with [3H]-DAMGO. 2...

journal_title：Brain research

authors： Ridd MJ,Fosbraey P,Kitchen I

更新日期：1998-12-14 00:00:00