Cutaneous stimuli releasing immunoreactive substance P in the dorsal horn of the cat.

abstract：:Ethylcholine aziridinium ion (AF64A) diluted in artificial perilymph, or artificial perilymph alone was infused into the cochlea of chinchillas. After a survival time of 7 days, the cochleas were fixed with aldehydes, post-fixed in osmium and embedded in epoxy resin for light and electron microscopy. The ultrastructur...

journal_title：Brain research

authors： Morley BJ,Spangler KM,Schneider BL,Javel E

更新日期：1991-03-22 00:00:00

abstract：:Excessive stimulation of neurons by glutamic acid initiates a destructive cascade of ion fluxes, cellular swelling, and death. Homeostatic mechanisms which rectify these disturbances depend largely upon transmembrane ion gradients maintained by Na+,K(+)-ATPase (NaP). We proposed that the neurotoxicity of glutamate is ...

journal_title：Brain research

authors： Brines ML,Robbins RJ

更新日期：1992-09-18 00:00:00

abstract：:Axonal flow of motoneurons was blocked in the sciatic nerve by the application of vinblastine at a low concentration (100 microM) not considered likely to cause axonal degeneration. The number of motoneurons expressing alpha-calcitonin gene-related peptide (CGRP) mRNA was significantly increased by vinblastine applica...

journal_title：Brain research

authors： Katoh K,Tohyama M,Noguchi K,Senba E

更新日期：1992-12-18 00:00:00

abstract：:The aim of the present study was to show that space perception depends on sensori-motor experience. We induced spatial biases by a non-conflictual lateralized sensori-motor task on twenty seven right-handed healthy volunteers (left-to-right readers). After a pre-test and before a post-test, which assessed visuo-motor ...

journal_title：Brain research

authors： Dupierrix E,Alleysson D,Ohlmann T,Chokron S

更新日期：2008-06-12 00:00:00

abstract：:Kindling is an experimental model for epilepsy in which repeated stimuli induce longer electrographic seizures and eventually cause behavioral convulsions. Although kindling has some features that are similar to chronic human epilepsy, it is not known whether this process plays a role in the development of chronic sei...

journal_title：Brain research

authors： Bertram EH,Cornett J

更新日期：1993-10-22 00:00:00

abstract：:The amygdala plays an important role in the regulation of motivational states, especially those associated with addiction. The amygdala also expresses high levels of brain-derived neurotrophic factor (BDNF), an activity-dependent neurotrophin that can influence the reinforcing and locomotor activating properties of ps...

journal_title：Brain research

authors： Meredith GE,Callen S,Scheuer DA

更新日期：2002-09-13 00:00:00

abstract：:Cortical projection areas and distribution and response characteristics of masseteric nerve-driven neurons (MDN) were studied by recording surface-evoked potentials and single neuronal activities elicited by stimulation of the contralateral masseteric nerve in cats. Neuronal activities of MDNs could be recorded in two...

journal_title：Brain research

authors： Iwata K,Itoga H,Ikukawa A,Hanashima N,Sumino R

更新日期：1985-09-02 00:00:00

abstract：:Intracerebroventricular (ICV) streptozotocin (STZ) treated rat has been described as a suitable model for sporadic Alzheimer's disease (AD). Central application of STZ has demonstrated behavioral and neurochemical features that resembled those found in human AD. Chronic treatments with antioxidants, acetylcholinestera...

journal_title：Brain research

authors： Ponce-Lopez T,Liy-Salmeron G,Hong E,Meneses A

更新日期：2011-12-02 00:00:00

abstract：:To provide evidence to support the calcium hypothesis of cerebral ischemia, we examined the effects of extracellular calcium and calcium antagonists (verapamil, flunarizine, nicardipine) on in vitro 'ischemia' using guinea pig hippocampal slices. As a model of in vivo ischemia we used a state of both glucose and oxyge...

journal_title：Brain research

authors： Amagasa M,Ogawa A,Yoshimoto T

更新日期：1990-08-27 00:00:00

abstract：:Outbred rat lines such as Wistar rats are commonly used for models of depressive disorders. Such rats arise from random mating schedules. Hence, genetic drift occurs in outbred populations which could lead to genotypic and phenotypic heterogeneity between rats from different vendors. Additionally, vendor specific rear...

journal_title：Brain research

authors： Theilmann W,Kleimann A,Rhein M,Bleich S,Frieling H,Löscher W,Brandt C

更新日期：2016-07-01 00:00:00

abstract：:To investigate to what extent the loss of cholinergic projections to the neocortex results in functional impairment in the target areas, local rates of cerebral glucose utilization were measured following excitotoxin lesions of the nucleus basalis magnocellularis (NBM) in the rat. Both unilateral and bilateral lesions...

journal_title：Brain research

authors： Orzi F,Diana G,Casamenti F,Palombo E,Fieschi C

更新日期：1988-10-11 00:00:00

abstract：:NO (nitric oxide) produced in limbic brain regions has important roles in the regulation of autonomic nervous system and HPA axis activity, anxiety, fear learning, long-term memory formation, and depression. NO is synthesized from l-arginine in a reaction catalyzed by nitric oxide synthase (NOS). Neuronal nitric oxide...

journal_title：Brain research

authors： Keser A,Balkan B,Gozen O,Kanit L,Pogun S

更新日期：2011-01-12 00:00:00

abstract：:This EEG study (N=33) examined event-related potentials associated with conflict between activated responses in the Stroop task, in order to examine the conflict monitoring theory of cognitive control, which predicts the strength of exerted control to be proportional to the detected level of conflict. However, existin...

journal_title：Brain research

authors： Chuderski A,Senderecka M,Kałamała P,Kroczek B,Ociepka M

更新日期：2016-11-01 00:00:00

abstract：:Transient global cerebral ischemia has been shown to induce marked changes in the polyamine pathway with a significant increase in putrescine, the product of the ornithine decarboxylase reaction. This study examined the relationship between tissue and extracellular polyamines and regional cerebral blood flow and brain...

journal_title：Brain research

authors： Başkaya MK,Rao AM,Dogan A,Donaldson D,Gellin G,Dempsey RJ

更新日期：1997-01-09 00:00:00

abstract：:Chromatography of partially purified choline acetyltransferase (CAT) over carboxymethyl cellulose may result in the loss of up to 95% of the enzyme activity. This loss of activity can be prevented by running the chromatographs at low protein concentration with a large gradient volume suggesting that interactions betwe...

journal_title：Brain research

authors： Cozzari C,Hartman BK

更新日期：1983-10-03 00:00:00

abstract：:Aging represents a major risk factor for numerous illnesses that are of increasing importance to society, including two of the most prevalent: diabetes and Alzheimer's disease. Studies have shown that diabetes is a risk factor for spontaneous Alzheimer's disease. While these studies suggest that diabetes can contribut...

journal_title：Brain research

authors： Oliveira LT,Leon GVO,Provance DW Jr,de Mello FG,Sorenson MM,Salerno VP

更新日期：2015-07-30 00:00:00

abstract：:An in vitro preparation of the medulla oblongata of the rat was used to examine the responses to reducing pH, at constant CO2, of neurons in several identified nuclei. Neurons in an area close to the ventral surface, which is thought to be the location of pH-sensitive central respiratory chemoreceptors, did not respon...

journal_title：Brain research

authors： Miles R

更新日期：1983-07-25 00:00:00

abstract：:Past research investigating the rostral ventromedial medulla (RVM) in anesthetized animals has found two distinct classes of cells, ON and OFF, noted for their distinct responses to noxious stimuli and to morphine. However, only one class (ON) has been found in the awake animal paradigm. We report in this paper that w...

journal_title：Brain research

authors： McGaraughty S,Reinis S,Tsoukatos J

更新日期：1993-02-26 00:00:00

abstract：:We have explored the potential neuroprotective effect of local lentiviraly-mediated overexpression of nerve growth factor (NGF) on in vivo long-term potentiation (LTP) in the rat hippocampus under pathological conditions. The suspension of lentiviral particles was prepared using a genetic construct containing the huma...

journal_title：Brain research

authors： Uzakov SS,Ivanov AD,Salozhin SV,Markevich VA,Gulyaeva NV

更新日期：2015-10-22 00:00:00

abstract：:We evaluated the role of neuropeptide Y (NPY), a potent endogenous orexigenic signal, in the ventromedial hypothalamic (VMH) lesion-induced hyperphagia in rats. To produce hyperphagia and excessive weight gain, adult female rats received bilateral electrolytic or sham lesions in the VMH. Concurrently, a permanent intr...

journal_title：Brain research

authors： Dube MG,Kalra PS,Crowley WR,Kalra SP

更新日期：1995-09-04 00:00:00

abstract：:The so-called on- and off-cells of the rostral ventromedial medulla (RVM) send their axons to the spinal dorsal horn. Activation of on-cells precedes and coincides with a facilitation, and activation of off-cells coincides with an inhibition, of withdrawal reflexes elicited by noxious agents. Considerable evidence sup...

journal_title：Brain research

authors： Salas R,Ramirez K,Tortorici V,Vanegas H,Vazquez E

更新日期：2018-05-01 00:00:00

abstract：:We have developed a computer-assisted method for analyzing the 2-deoxyglucose (2-DG) autoradiograms of mice olfactory bulbs. The purpose of the study was to numerize the maps of glomerular activation in order to achieve a statistical comparison of the glomerular patterns evoked by different stimuli. The spatial distri...

journal_title：Brain research

authors： Royet JP,Sicard G,Souchier C,Jourdan F

更新日期：1987-08-04 00:00:00

abstract：:Rat central nervous system (CNS) tissue sections were immunostained by the peroxidase-anti-peroxidase (PAP) method using a rabbit serum directed against rat liver 5'-nucleotidase. In paraffin sections from the brains of 60-day-old rats 5'-nucleotidase immunoreactivity occurred in the same white-matter regions as myeli...

journal_title：Brain research

authors： Cammer W,Sacchi R,Kahn S

更新日期：1985-05-01 00:00:00

abstract：:Cerebral venous thrombosis (CVT) is a rare form of cerebral stroke that causes a variety of symptoms, ranging from mild headache to severe morbidity or death in the more severe forms. The use of anti-coagulant or thrombolytic agents is the classical treatment for CVT. However, the development of new therapies for the ...

journal_title：Brain research

authors： Rashad S,Niizuma K,Sato-Maeda M,Fujimura M,Mansour A,Endo H,Ikawa S,Tominaga T

更新日期：2018-11-15 00:00:00

abstract：:Maternal cocaine abuse has several deleterious effects in the newborn, including perinatal asphyxia, hypoxia, and hypercapnia. We hypothesized that chronic cocaine exposure during development may alter cerebral blood flow (CBF) regulation. We studied 16 neonatal rabbits that had received cocaine (20 mg/kg, i.p. b.i.d....

journal_title：Brain research

authors： Feuer P,Loeb A,Monitto CL,O'Rourke M,Kurth CD

更新日期：1997-04-25 00:00:00

abstract：:We electrically stimulated individual Mauthner (M-) cells to determine their motor contribution to C-starts of swimming goldfish. In comparison with sensory-evoked C-starts, M-reflexes triggered by electrical stimulation of single M-cells were significantly weaker and less variable. Stage 1 turns were both longer in d...

journal_title：Brain research

authors： Nissanov J,Eaton RC,DiDomenico R

更新日期：1990-05-28 00:00:00

abstract：:Neurons from many brainstem nuclei involved in respiratory control increase their firing rate in response to acidosis in vitro, suggesting that they are central chemoreceptors. This property has been considered to be either unique to neurons involved in respiratory control, or at least very unusual for non-respiratory...

journal_title：Brain research

authors： Wang W,Richerson GB

更新日期：2000-03-31 00:00:00

abstract：:Binge-like ethanol treatment of septal neurons blunts GABAAR-mediated miniature postsynaptic currents (mPSCs), suggesting it arrests synaptic development. Ethanol may disrupt postsynaptic maturation by blunting feedback signaling through immature GABAARs. Here, the impact of ethanol on the sensitivity of mPSCs to zolp...

journal_title：Brain research

authors： DuBois DW,Trzeciakowski JP,Parrish AR,Frye GD

更新日期：2006-05-17 00:00:00

abstract：:Accumulating evidence suggests that the neuropeptide substance P (SP) and its principal receptor neurokinin 1 (NK1) play a specific role in the behavioral response to opioids and stress that may help to initiate and maintain addictive behavior. In animal models, the NK1 receptor is required for opioids to produce thei...

journal_title：Brain research

authors： Commons KG

更新日期：2010-02-16 00:00:00

abstract：:In kittens, but not in adult cats, depriving one eye of pattern vision by suturing the lids shut (monocular deprivation or MD) for one week reduces the proportion of binocular units in the visual cortex. A sensitivity of cortical units in adult cats to MD can be produced by infusing exogenous monoamines into the visua...

journal_title：Brain research

authors： McCall MA,Tieman DG,Hirsch HV

更新日期：1982-11-04 00:00:00