Two distinct unit activity responses to morphine in the rostral ventromedial medulla of awake rats.

Abstract:

:Past research investigating the rostral ventromedial medulla (RVM) in anesthetized animals has found two distinct classes of cells, ON and OFF, noted for their distinct responses to noxious stimuli and to morphine. However, only one class (ON) has been found in the awake animal paradigm. We report in this paper that we have found both the ON and OFF cell responses to morphine in the awake rat.

journal_name

Brain Res

journal_title

Brain research

authors

McGaraughty S,Reinis S,Tsoukatos J

doi

10.1016/0006-8993(93)90385-z

subject

Has Abstract

pub_date

1993-02-26 00:00:00

pages

331-3

issue

1-2

eissn

0006-8993

issn

1872-6240

pii

0006-8993(93)90385-Z

journal_volume

604

pub_type

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