Axonal flow blockade induces alpha-CGRP mRNA expression in rat motoneurons.

abstract：:The distribution and relative specificity of cholecystokinin (CCK) receptors in the rat brain was mapped by in vitro autoradiography with [125I]CCK-33. We identified two distinct binding patterns, suggesting two CCK receptor types. The first is widespread and relatively non-specific. The second, localized to a few sub...

journal_title：Brain research

authors： Moran TH,Robinson PH,Goldrich MS,McHugh PR

更新日期：1986-01-01 00:00:00

abstract：:The effect of a dihydropyridine Ca2+ antagonist, cilnidipine, on voltage-dependent Ca2+ channels was studied in acutely dissociated rat CA1 pyramidal neurons using the nystatin-perforated patch recording configuration under voltage-clamp conditions. Cilnidipine had no effect on low-voltage-activated (LVA) Ca2+ channel...

journal_title：Brain research

authors： Murai Y,Uneyama H,Ishibashi H,Takahama K,Akaike N

更新日期：2000-01-31 00:00:00

abstract：:The main goal of the present study was to analyse the effects of (+/-)-huprine X ((+/-)-HX) and galantamine (GAL), with potentiating action on nicotinic receptors, and huperzine A (HPA), devoid of nicotinic activity, on [3H]-acetylcholine ([3H]-ACh) release in striatal slices of rat brain. All compounds are non-covale...

journal_title：Brain research

authors： Roman S,Badia A,Camps P,Muñoz-Torrero D,Clos MV

更新日期：2005-11-09 00:00:00

abstract：:To elucidate the anatomical distribution of the serotonergic neurotransmitter system, we identified serotonin transporter (5-HTT) in the hippocampus of rats and monkeys by immunohistochemistry. A widespread and heterogeneous distribution of 5-HTT-immunoreactive fine fibers was noted in the rat brain. However, in monke...

journal_title：Brain research

authors： Owashi T,Iritani S,Niizato K,Ikeda K,Kamijima K

更新日期：2004-06-04 00:00:00

abstract：:The ontogeny of muscarinic cholinergic receptors was studied in primary cultures of dissociated rat hippocampal cells. The specific [3H]quinuclidinyl benzilate [( 3H]QNB) to intact cells was detected after two days in culture. Scatchard analysis revealed only a unique binding site at all of the days tested, with a ver...

journal_title：Brain research

authors： Fernandez-Tomé P,Segal M

更新日期：1987-09-01 00:00:00

abstract：:Sensory fibers trapped in nerve-end neuromas become abnormally excitable, and produce an ectopic discharge which is believed to contribute to paresthesias and pain associated with chronic nerve injury in man. Here we report that stimulation of injured nerves can alter this discharge, directly by antidromic invasion of...

journal_title：Brain research

authors： Lisney SJ,Devor M

更新日期：1987-07-07 00:00:00

abstract：:Astrocytes produce and bind endothelins (ETs), suggesting that these cells have ET autoregulatory and eliminatory functions. To further investigate these functions in primary rat astrocytes, ET-1 levels in the cell culture media (RIA/HPLC) and intracellular content of ET-1 mRNA (RT PCR) were measured under basal and s...

journal_title：Brain research

authors： Hasselblatt M,Kamrowski-Kruck H,Jensen N,Schilling L,Kratzin H,Sirén AL,Ehrenreich H

更新日期：1998-03-02 00:00:00

abstract：:In this study, the effects of chronic morphine administration (20-30 days) on long-term potentiation (LTP) were investigated at the Schaffer collateral-CA1 pyramidal cell synapses of the rat hippocampal slices. Orthodromic population spike (OPS) amplitude and delay (peak latency) were measured as indices of increase i...

journal_title：Brain research

authors： Mansouri FA,Motamedi F,Fathollahi Y

更新日期：1999-01-09 00:00:00

abstract：:The present study is designed to investigate the effects of preconditioning with different doses of hydrogen peroxide (H2O2) on oxidative stress-induced apoptosis and the changes in mitochondrial membrane potential (MMP), intracellular reactive oxygen species (ROS) level, and expression of Bcl-2 during H2O2 preconditi...

journal_title：Brain research

authors： Tang XQ,Feng JQ,Chen J,Chen PX,Zhi JL,Cui Y,Guo RX,Yu HM

更新日期：2005-09-28 00:00:00

abstract：:Small reductions in temperature have been shown to improve neurologic recovery after ischemia. We have examined the effect of temperature on biochemical and physiological changes during hypoxia using rat hippocampal slices as a model system. The postsynaptic population spike recorded from the CA1 pyramidal cell region...

journal_title：Brain research

authors： Amorim P,Cottrell JE,Kass IS

更新日期：1999-10-09 00:00:00

abstract：:Unilateral microinjections (0.20 microliter) of the excitatory amino acids (EAA), L-aspartate (ASP), D,L-homocysteate (DLH) or kainate (KA) were made into the midbrain of freely moving cats. Injections of DLH (20 nmol) or ASP (200 nmol) made within the midbrain periaqueductal grey matter (PAG) consistently elicited a ...

journal_title：Brain research

authors： Bandler R,Carrive P

更新日期：1988-01-26 00:00:00

abstract：:The anteroventral subdivision of the medial amygdala (MeAV) is one of the vomeronasal structures involved in the control of hormonally dependent behaviors such as sexual and agonistic behaviors in rats. The present study investigates some anatomical and neurochemical parameters of this nucleus (volume, number of neuro...

journal_title：Brain research

authors： Carrillo B,Pinos H,Guillamón A,Panzica G,Collado P

更新日期：2007-05-30 00:00:00

abstract：:The neuroprotection research in the last 2 decades has witnessed a growing interest in the functions of estrogens as neuroprotectants against neurodegenerative diseases including stroke. The neuroprotective action of estrogens has been well demonstrated in both in vitro and in vivo models of ischemic stroke. However, ...

journal_title：Brain research

authors： Liu R,Yang SH

更新日期：2013-06-13 00:00:00

abstract：:The nictitating membrane response to periocular electrostimulation was investigated in anesthetized and paralyzed rabbits. Recordings from the abducens nerve, which carries the fibers innervating retractor bulbi muscles that are primarily involved in this reflex, showed two distinct volleys to effective stimulation: a...

journal_title：Brain research

authors： Berthier NE,Moore JW

更新日期：1983-01-10 00:00:00

abstract：:Inoculation of the tail base of rats with Mycobacterium butyricum led to an arthritic swelling and inflammation of the limbs which displayed a hyperalgesia to noxious pressure: these effects peaked at 3 weeks postinoculation. In vitro autoradiography of coronal sections of rat brain was used for a parallel determinati...

journal_title：Brain research

authors： Millan MJ,Morris BJ,Colpaert FC,Herz A

更新日期：1987-07-28 00:00:00

abstract：:Deferoxamine (DFO) has shown therapeutic promise for the treatment of Parkinson׳s disease (PD) as it has reduced both behavioral and biochemical deficits when injected into the brain of rodent models of PD. Intranasally administered DFO targets the brain directly but non-invasively and has been effective in animal mod...

journal_title：Brain research

authors： Fine JM,Forsberg AC,Renner DB,Faltesek KA,Mohan KG,Wong JC,Arneson LC,Crow JM,Frey WH 2nd,Hanson LR

更新日期：2014-07-29 00:00:00

abstract：:We investigated c-Met expression in cultured astrocytes and their regulation by cytokines. Immunocytochemistry revealed that c-Met was expressed in cultured astrocytes. Western blotting revealed that acidic and basic fibroblast growth factor (FGF) enhanced and hepatocyte growth factor (HGF) reduced c-Met expression. R...

journal_title：Brain research

authors： Shimazaki K,Yoshida K,Hirose Y,Ishimori H,Katayama M,Kawase T

更新日期：2003-02-07 00:00:00

abstract：:Leukocyte behavior in the cerebral microvasculature following vessel occlusion has not been fully elucidated. The purpose of this study was to investigate the effects of cilostazol on leukocyte behavior (rolling and adhesion) in murine cerebral microvessels following transient bilateral carotid artery occlusion using ...

journal_title：Brain research

authors： Fukuoka T,Hayashi T,Hirayama M,Maruyama H,Tanahashi N

更新日期：2014-01-16 00:00:00

abstract：:Because brainstem auditory evoked potentials (BAEPs) are frequently recorded in anesthetized animals and humans, it is important to become familiar with the effects on the BAEP of drugs used during anesthesia, including pre-anesthetics. The dose-dependent and stimulus intensity-dependent effects on the BAEP of a pre-a...

journal_title：Brain research

authors： Church MW,Gritzke R

更新日期：1988-07-26 00:00:00

abstract：:Systemic injections of the dopamine antagonist haloperidol (0.1-2.5 mg/kg) induced a dose dependent increase in Fos-like immunoreactivity (FLI) in the internal segment of the globus pallidus (GPi) and in the substantia nigra (SN) of cynomolgus monkeys. These findings are consistent with models of basal ganglia organiz...

journal_title：Brain research

authors： Wirtshafter D,Asin KE

更新日期：1999-07-24 00:00:00

abstract：:In the present functional magnetic resonance imaging (fMRI) study, we aimed to evaluate whether distinct regions of the hippocampus were associated with spatial memory for items presented in different locations of the visual field. In Experiment 1, during the study phase, participants viewed abstract shapes in the lef...

journal_title：Brain research

authors： Jeye BM,MacEvoy SP,Karanian JM,Slotnick SD

更新日期：2018-05-15 00:00:00

abstract：:Motoneurons in the lumbar spinal cord of chick embryos 6 days old, the age when their cell death starts, were labeled in vivo by retrograde axonal transport of horseradish peroxidase (HRP) and then cultured as cord fragments or isolated cells. In Eagle's minimum essential medium with no additives, spinal cord cells su...

journal_title：Brain research

authors： Tanaka H,Obata K

更新日期：1983-09-01 00:00:00

abstract：:We have previously found that crocin (crocetin di-gentiobiose ester) antagonizes the inhibitory effect of ethanol on long-term potentiation in the rat hippocampus in vivo and in vitro. To explore mechanisms underlying the antagonism of crocin against ethanol, we investigated the effects of ethanol and crocin on synapt...

journal_title：Brain research

authors： Abe K,Sugiura M,Shoyama Y,Saito H

更新日期：1998-03-16 00:00:00

abstract：:Two rat lines bred for kindling susceptibility were previously observed to engage in different behavioral strategies in tests of emotionality. In order to extend past research on defensive behaviors in these strains which largely used males, Fast- and Slow-kindling females were assessed for anxiety-like behaviors in a...

journal_title：Brain research

authors： Runke D,McIntyre DC

更新日期：2008-11-13 00:00:00

abstract：:Norepinephrine (NE) and 3-methoxy-4-hydroxyphenylglycol (MOPEG) were determined in medio-basal hypothalamus of adult male rats using high-performance liquid chromatography to study nutritional modulation of noradrenergic turnover. Acute starvation, as well as 3 weeks of semistarvation with a low-protein high-carbohydr...

journal_title：Brain research

authors： Schweiger U,Warnhoff M,Pirke KM

更新日期：1985-06-03 00:00:00

abstract：:The intracellular injection technique of HRP with simultaneous recordings of intracellular potential was applied to the crab X-organ-sinus gland peptidergic neurosecretory neurons. At least two classes of neurons were discriminated from the usual type of neurosecretory neurons morphologically as well as electrophysiol...

journal_title：Brain research

authors： Nagano M

更新日期：1986-01-08 00:00:00

abstract：:Chronic food restriction lowers the threshold for lateral hypothalamic electrical self-stimulation (LHSS). This effect has previously been interpreted to reflect a sensitization of reward. In the present study a curve-shift method was used to explicitly differentiate effects of food restriction on brain stimulation re...

journal_title：Brain research

authors： Abrahamsen GC,Berman Y,Carr KD

更新日期：1995-10-16 00:00:00

abstract：:Nitric oxide (NO) is a neuronal messenger that it is thought to be involved in the nociceptive transmission modulation. The activity of nicotinamide adenine dinucleotide phosphate diaphorase (NADPH-d) was shown to be identical to NOS activity in the brain. Since the periaqueductal gray matter (PAG) plays an important ...

journal_title：Brain research

authors： Rodella L,Rezzani R,Agostini C,Bianchi R

更新日期：1998-05-18 00:00:00

abstract：:The hypoxia tracer fluorine-18 fluoromisonidazole ([18F]FMISO) and its tritiated counterpart ([(3)H]FMISO) have been used as markers of potentially salvageable brain (ischemic penumbra) after stroke. In experimental models, the dynamics and half-life of [3H]FMISO allow concurrent histology after 24 h. Our aim was to f...

journal_title：Brain research

authors： Spratt NJ,Donnan GA,Howells DW

更新日期：2009-09-08 00:00:00

abstract：:Sprague-Dawley dams were treated with 3 v/v % ethanol in liquid diet from the 8th day gestation through 3 weeks nursing period. Offsprings, ages 1, 2 and 3 weeks, and their dams were studied. Brain weights and their total proteins were not affected by this ethanol treatment. Total enolase activity/mg protein and its i...

journal_title：Brain research

authors： Harada K,Adams V,Okamoto M

更新日期：1992-05-15 00:00:00