The nictitating membrane response: an electrophysiological study of the abducens nerve and nucleus and the accessory abducens nucleus in rabbit.

Abstract:

:The nictitating membrane response to periocular electrostimulation was investigated in anesthetized and paralyzed rabbits. Recordings from the abducens nerve, which carries the fibers innervating retractor bulbi muscles that are primarily involved in this reflex, showed two distinct volleys to effective stimulation: a short duration volley with a minimum latency of approximately 4 ms and a longer duration volley beginning approximately 10 ms after stimulus onset and lasting up to 25 ms. Recordings of antidromically evoked field potentials via microelectrodes indicated large responses to abducens nerve stimulation in the vicinity of the accessory abducens nucleus. Single unit recordings from the accessory abducens nucleus produced spike trains with minimal latencies of 3.7-5 ms to eyeshock. The latency of spike discharge was inversely related to stimulus current. Units in the abducens nucleus did not show stimulus-elicited spiking, suggesting that the accessory abducens, but not the abducens, is primarily involved in the reflex pathway. Transverse knife cuts which separated caudal areas of the sensory trigeminal complex from the accessory abducens nucleus did not attenuate the efferent volley to suprathreshold stimulation, suggesting that more rostral components of the trigeminal complex are primarily involved in the reflex pathway.

journal_name

Brain Res

journal_title

Brain research

authors

Berthier NE,Moore JW

doi

10.1016/0006-8993(83)91143-5

subject

Has Abstract

pub_date

1983-01-10 00:00:00

pages

201-10

issue

2

eissn

0006-8993

issn

1872-6240

pii

0006-8993(83)91143-5

journal_volume

258

pub_type

杂志文章
  • MicroRNA overexpression increases cortical neuronal vulnerability to injury.

    abstract::Previously we reported that several microRNAs (miRNA) are upregulated following experimentally induced traumatic brain injury (TBI) using both in vivo and in vitro approaches. Specific miRNAs were found to be sensitive to therapeutic hypothermia and may therefore be important targets for neuroprotective strategies. In...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2013.08.011

    authors: Truettner JS,Motti D,Dietrich WD

    更新日期:2013-10-02 00:00:00

  • Occipital EEG correlates of conscious awareness when subjective target shine-through and effective visual masking are compared: bifocal early increase in gamma power and speed-up of P1.

    abstract::Neural correlates of conscious awareness can be comfortably studied when awareness of the target stimuli is a varying dependent variable in the experimental conditions where the key independent variables are kept invariant. We presented vernier targets backward masked by an invariant grating with invariant SOA. EEG da...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2008.12.085

    authors: Aru J,Bachmann T

    更新日期:2009-05-19 00:00:00

  • Evidence for a role of endogenous cannabinoids in the modulation of acute and tonic pain sensitivity.

    abstract::The competitive CB1 receptor antagonist SR141716A was used to test the hypothesis that endogenous cannabinoids modulate tonic pain sensitivity. Pretreatment with the antagonist significantly enhanced the response to a chemical nociceptive stimulus in the formalin test. Postreatment with the antagonist 5 min following ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(98)01031-2

    authors: Strangman NM,Patrick SL,Hohmann AG,Tsou K,Walker JM

    更新日期:1998-12-07 00:00:00

  • Alteration of the electrophysiological activity in sympathetic ganglia infected with a neurotropic virus. I. Presynaptic origin of the spontaneous bioelectric activity.

    abstract::The bioelectric activity of the rat superior cervical ganglion (SCG) infected with pseudorabies virus (PRV) was examined in vitro 30-38 h after inoculation. Simultaneous intra- and extracellular recordings on the internal (ICN) and external carotid nerves (ECN) revealed a synchronized spontaneous activity. This synchr...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(82)90642-4

    authors: Kiraly M,Dolivo M

    更新日期:1982-05-20 00:00:00

  • Effect of amniotic-fluid ingestion on vaginal-cervical-stimulation-induced Fos expression in female rats during estrus.

    abstract::Placental Opioid-Enhancing Factor (POEF) is a substance found in amniotic fluid (AF) that, when ingested, potentiates opioid-mediated, but not non-opioid-mediated, hypoalgesia. Vaginal-cervical stimulation (VCS) produces a stimulus-bound, partially opioid-mediated hypoalgesia that previous research has shown to be pot...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2010.12.055

    authors: Hoey RF,Hurley SW,Daniels D,Kristal MB

    更新日期:2011-02-28 00:00:00

  • Serotonin abnormalities in Dravet syndrome mice before and after the age of seizure onset.

    abstract::Dravet syndrome (DS) is a genetic form of severe epilepsy often associated with mutation of the SCN1A gene encoding the voltage gated sodium channel Nav1.1. Typically refractive to conventional therapy, serotonin neurotransmission may be an innovative target for treatment. To further understand the role of serotonin i...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2019.146399

    authors: Hatini PG,Commons KG

    更新日期:2019-12-01 00:00:00

  • Roles of brain angiotensins II and III in thirst and sodium appetite.

    abstract::The current study examined the effects of intracerebroventricular (icv) infused aminopeptidase-resistant analogs of angiotensin II (AngII) and angiotensin III (AngIII) on thirst and sodium appetite. The analogs, [D-Asp1D-Arg2]AngII and [D-Arg1]AngIII, were further protected from degradation by pretreatment with the am...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2005.08.032

    authors: Wilson WL,Roques BP,Llorens-Cortes C,Speth RC,Harding JW,Wright JW

    更新日期:2005-10-26 00:00:00

  • Behavioral changes in 2-month-old rats following prenatal exposure to antibodies against synaptic membranes.

    abstract::Two-month-old male offspring of rats injected intravenously on day 19 of gestation with antiserum to synaptic membrane fraction showed marked behavioral deficits on a DRL (differential reinforcement at low rates) training paradigm. These behavioral deficits included perseveration, slow acquisition rates, and poor rete...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(75)90325-x

    authors: Karpiak SE Jr,Rapport MM

    更新日期:1975-07-18 00:00:00

  • Morphine-induced suppression of conditioned stimulus intake: effects of stimulus type and insular cortex lesions.

    abstract::Intake of an unconditionally preferred taste stimulus (e.g., saccharin) is reduced by contingent administration of a drug of abuse (e.g., morphine). We examined the influence of insular cortex (IC) lesions on morphine-induced suppression of an olfactory cue and two taste stimuli with different levels of perceived inna...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2009.07.033

    authors: Lin JY,Roman C,Reilly S

    更新日期:2009-10-06 00:00:00

  • Quantitative analysis of glutathione in rat central nervous system: comparison of GSH in infant brain with that in adult brain.

    abstract::Reduced glutathione (GSH) plays an important role in cellular protection against damage from free radicals and other electrophiles. GSH in the rat central nervous system was quantitatively analyzed. In adult brain, tissue from the cerebellum and cerebrum had higher GSH levels than that from the brainstem and spinal co...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(90)90178-e

    authors: Kudo H,Kokunai T,Kondoh T,Tamaki N,Matsumoto S

    更新日期:1990-03-19 00:00:00

  • Spinal cord neurons are vulnerable to rapidly triggered kainate neurotoxicity in vitro.

    abstract::Initial studies found glutamate injury to murine spinal cultures (14-17 days in vitro) to reflect contributions of both NMDA and AMPA/kainate receptors. Subsequent experiments found the spinal cultures to be more sensitive than cortical cultures to injury from prolonged low level kainate exposures, and, unlike cortica...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(95)00532-u

    authors: Yin HZ,Park DD,Lindsay AD,Weiss JH

    更新日期:1995-08-21 00:00:00

  • Strain differences in the behavioral responses of male rats to chronically administered methylphenidate.

    abstract::Genetic variability in the behavioral responses of experimental subjects to psychostimulants such as amphetamine and cocaine have been reported. However, genetic differences in the locomotor responses of rat strains to methylphenidate (MPD), a commonly used psychostimulant in the treatment of attention deficit/hyperac...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(02)04240-3

    authors: Yang PB,Amini B,Swann AC,Dafny N

    更新日期:2003-05-09 00:00:00

  • Role of V1a vasopressin receptors in the control of aggression in Syrian hamsters.

    abstract::The present study investigated the hypothesis that social isolation increases aggression by increasing the number of V1a vasopressin receptors in the anterior hypothalamus (AH). Male hamsters were randomly assigned to a group that was allowed to interact with a small nonaggressive hamster three times each week for 3 w...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2005.12.081

    authors: Albers HE,Dean A,Karom MC,Smith D,Huhman KL

    更新日期:2006-02-16 00:00:00

  • Abnormal gene expression in cerebellum of Npc1-/- mice during postnatal development.

    abstract::Niemann-Pick Type C (NPC) disease is an autosomal recessive neurodegenerative disorder with abnormal lipid storage as the major cellular pathologic hallmark. Genetic analyses have identified mutations in NPC1 gene in the great majority of cases, while mutations in NPC2 account for the remainders. Yet little is known r...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2010.02.019

    authors: Liao G,Wen Z,Irizarry K,Huang Y,Mitsouras K,Darmani M,Leon T,Shi L,Bi X

    更新日期:2010-04-14 00:00:00

  • Enhanced neural response by adult rats to odors experienced early in life.

    abstract::The enhanced olfactory bulb neural response to familiar odors by young rats persists into adulthood. Ninety-day-old rats who had received neonatal odor exposure had an enhanced uptake of [14C]2-deoxyglucose (2-DG) when exposed to the familiar odor. The odor-familiar rats did not have an increased respiration rate duri...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(86)90384-7

    authors: Coopersmith R,Leon M

    更新日期:1986-04-23 00:00:00

  • Deferoxamine improves spatial memory performance following experimental brain injury in rats.

    abstract::Traumatic brain injury (TBI) causes impairments of both motor and spatial memory performances. Research is only beginning to reveal the biochemical mechanism(s) underlying these deficits. It has been postulated that reactive oxygen species such as the superoxide and hydroxyl radicals, as well as the peroxynitrite anio...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(95)01500-0

    authors: Long DA,Ghosh K,Moore AN,Dixon CE,Dash PK

    更新日期:1996-04-22 00:00:00

  • Unexpected expression of orexin-B in basal conditions and increased levels in the adult rat hippocampus during pilocarpine-induced epileptogenesis.

    abstract::Orexin-A (OX-A) and -B (OX-B) peptides present in the hippocampus are considered to be exclusively contained in fibers arising from hypothalamus neurons, which were established as the only source of orexins (OXs). Because OX-A is known to exert excitatory actions in the hippocampus, we hypothesized that the level of O...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2006.06.075

    authors: Morales A,Bonnet C,Bourgoin N,Touvier T,Nadam J,Laglaine A,Navarro F,Moulin C,Georges B,Pequignot JM,Bezin L

    更新日期:2006-09-13 00:00:00

  • Effects of phencyclidine administration on behavior and brain neurotensin-like immunoreactivity in rats.

    abstract::The effects of acute and chronic phencyclidine (PCP) administration on neurotensin-like immunoreactivity (NTLI) were investigated in discrete regions of rat brain. Both acute and chronic administration of PCP induced high locomotor activity, stereotypy and ataxia. On PCP administration, NTLI decreased significantly in...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(85)91601-4

    authors: Wachi M,Okuda M,Togashi S,Fuwano S,Miyashita O

    更新日期:1985-05-06 00:00:00

  • Nuclear and cytoplasmic Ca2+ signals in developing rat dorsal root ganglion neurons studied in excised tissue.

    abstract::Confocal microscopy and the Ca(2+)-sensitive fluorescent dye fluo-3 were used to study subcellular Ca2+ signals in embryonic, neonatal, and adult dorsal root ganglion (DRG) neurons in excised dorsal root ganglia. Optical images obtained from isolated whole embryonic and neonatal ganglia revealed a marked variability i...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(94)91444-3

    authors: Utzschneider DA,Rand MN,Waxman SG,Kocsis JD

    更新日期:1994-01-28 00:00:00

  • Membrane currents elicited by the epileptogenic drug pentylenetetrazole in the native oocyte of Xenopus laevis.

    abstract::The effects of the epileptogenic agent pentylenetetrazole (PTZ) on membrane currents of native oocytes of Xenopus laevis were studied. PTZ elicits a response that consists of two inward currents. The first one is interpreted to be due to a decrease of potassium permeability since: (1) the input resistance is increased...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(91)90225-k

    authors: Madeja M,Musshoff U,Kuhlmann D,Speckmann EJ

    更新日期:1991-07-05 00:00:00

  • Decreased catalepsy response to haloperidol in the genetically dystonic (dt) rat.

    abstract::The rat mutant dystonic displays an autosomal recessive neurological disease characterized by slow, twisting movements of the limbs and trunk. Rats displaying clinical signs also show a decreased behavioral response to the dopaminergic blocker, haloperidol. Investigation of the development of the cataleptic response t...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(84)90920-x

    authors: McKeon TW,Lorden JF,Oltmans GA,Beales M,Walkley SU

    更新日期:1984-08-06 00:00:00

  • Plasma nerve growth factor access to the postnatal central nervous system.

    abstract::The accessibility of macromolecules to the postnatal mammalian central nervous system is a subject of controversy and importance. One of the biologically important macromolecules in neural development, nerve growth factor (NGF), is thought to be unable to cross the blood-brain barrier in postnatal mammals. In this stu...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(93)91775-n

    authors: Fabian RH,Hulsebosch CE

    更新日期:1993-05-14 00:00:00

  • Distribution of neurturin mRNA and immunoreactivity in the peripheral tissues of adult rats.

    abstract::Neurturin (NTN) is a recently discovered neurotrophic factor related to glial cell line-derived neurotrophic factor (GDNF) and has a wide spectrum of biological roles in different types of neurons in the central and peripheral nervous systems. However, information on its expression in peripheral tissues has been limit...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(99)01590-5

    authors: Xian CJ,Huang BR,Zhou XF

    更新日期:1999-07-24 00:00:00

  • Androgen action in fetal mouse spinal cord cultures: metabolic and morphologic aspects.

    abstract::Morphologic and metabolic aspects of androgen effects on the developing spinal cord were studied in organotypic cultures of the E13 (embryonic day 13) fetal mouse lumbosacral spinal cord, maintained as either hemisected, homologous explant pairs co-cultured with bulbocavernosus muscle (morphologic studies), or as whol...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(87)90769-4

    authors: Hauser KF,MacLusky NJ,Toran-Allerand CD

    更新日期:1987-03-17 00:00:00

  • Differential expression of CPD1 during postnatal development in the mouse cerebellum.

    abstract::Several regulated mRNAs were detected by applying differential display to the mouse cerebellum during postnatal development. One cDNA fragment, referred to as CPD1 (GenBank U89345), was characterized and cloned. Northern blots showed maximum mRNA expression at postnatal day seven (P7). The mRNA encodes a protein of 26...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(01)02351-4

    authors: Radrizzani M,Vilá-Ortiz G,Cafferata EG,Di Tella MC,González-Guerrico A,Perandones C,Pivetta OH,Carminatti H,Idoyaga Vargas VP,Santa-Coloma TA

    更新日期:2001-07-13 00:00:00

  • Acute effects of 1-methyl-1,4-phenylpyridinium ion (MPP+) on purine metabolism in rat striatum studied in vivo using the microdialysis technique.

    abstract::In order to obtain further insight into the interactions between the purinergic and dopaminergic pathways in the striatum, we studied both metabolisms simultaneously, using a microdialysis technique in 1-methyl-1,4-phenylpyridinium ion (MPP+) unilaterally-denervated conscious rats. In these rats the contralateral side...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(89)90052-8

    authors: Ballarin M,Reiriz J,Ambrosio S,Camps M,Blesa R,Mahy N

    更新日期:1989-03-27 00:00:00

  • Ultrastructural double-labeling demonstrates synaptic contacts between dopaminergic terminals and substance P-containing striatal neurons in pigeons.

    abstract::Immunohistochemical studies in rats have demonstrated dopaminergic input onto medium spiny neurons of the striatum. Medium spiny neurons, however, are known to consist of two major neuropeptide-specific types, those containing substance P (SP) and those containing enkephalin. Although both of these types have been sho...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(92)90490-z

    authors: Karle EJ,Anderson KD,Reiner A

    更新日期:1992-02-14 00:00:00

  • Non-oriented cells of the striate cortex activated during smooth pursuit eye movements and steady fixations in behaving monkeys.

    abstract::Extracellular recordings were carried out in the primary visual cortex of behaving monkeys. Neurons were activated by moving a visual stimulus on their receptive fields during periods of steady fixation and by moving their receptive fields (smooth pursuit eye movements) on a motionless visual stimulus. Regarding non-o...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(83)90772-2

    authors: Galletti C,Squatrito S,Battaglini PP,Maioli MG

    更新日期:1983-01-31 00:00:00

  • Influences of pituitary-adrenal hormones on kindling.

    abstract::The kindling process represents a progressively augmenting electrical and behavioral response to brain stimulation, that has been proposed as a model for the development of epileptogenesis. The first experiment examined the effects of hypophysectomy on the kindling process. The effects of hypophysectomy were found to ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(79)91032-1

    authors: Rose RP,Morell F,Hoeppner TJ

    更新日期:1979-06-22 00:00:00

  • Effect of oxotremorine on local cerebral glucose utilization in motor system regions of the rat brain.

    abstract::The [14C]2-deoxy-D-glucose technique was used to test the effects of central muscarinic stimulation on local cerebral glucose utilization (LCGU) in rats. Systemic administration of the muscarinic agonist oxotremorine (OXO, 0.7 mg/kg, ip) increased LCGU in brain regions involved in motor function: the sensorimotor cort...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(81)91100-8

    authors: Dow-Edwards D,Dam M,Peterson JM,Rapoport SI,London ED

    更新日期:1981-12-07 00:00:00