Two brain cholecystokinin receptors: implications for behavioral actions.

abstract：:The effects of the putative dopaminergic antagonist, haloperidol (0.01-10 mg/kg, i.v.), on cerebral glucose utilization in 43 anatomically discrete regions of the rat brain have been examined by the quantitative autoradiographic 2-deoxyglucose technique. Dose-dependent reductions in glucose utilization were observed i...

journal_title：Brain research

authors： McCulloch J,Savaki HE,Sokoloff L

更新日期：1982-07-08 00:00:00

abstract：:Alteration of blood-brain barrier (BBB) permeability by 2450 MHz CW microwaves was assessed semi-quantitatively after intravenous injection of horseradish peroxidase (HRP) and exposure of conscious, unrestrained rats to incident power densities of 0, 20 or 65 mW/cm2 for 30, 90 or 180 min. Additional rats were exposed ...

journal_title：Brain research

authors： Williams WM,Del Cerro M,Michaelson SM

更新日期：1984-05-01 00:00:00

abstract：:Freeze-fracture examination of nodes of Ranvier from adult rat optic nerve demonstrates the presence of astrocytic processes at the majority of nodes of Ranvier. Astrocytic processes often run along the entire length of the nodal gap, although they do not necessarily encircle the entire nodal circumference. The E- and...

journal_title：Brain research

authors： Waxman SG,Black JA

更新日期：1984-08-06 00:00:00

abstract：:Zif268 transcription factor is expressed throughout Cebus apella visual cortex at high basal levels. Monocular eyelid suture alters the levels of Zif268 on neurons connected to the deprived eye, revealing ocular dominance columns in the striate cortex of Cebus as previously demonstrated in Old World monkeys (Chaudhuri...

journal_title：Brain research

authors： Silveira LC,de Mátos FM,Pontes-Arruda A,Picanço-Diniz CW,Muniz JA

更新日期：1996-09-02 00:00:00

abstract：:Diazoxide (DZ), a highly selective opener of the mitochondrial ATP-sensitive potassium (mitoK(ATP)) channel, has neuroprotective effects. However, the mechanism of DZ protecting hippocampal neurons against cell death in pilocarpine-induced seizures is unknown. In this study, we investigated DZ attenuating neuronal los...

journal_title：Brain research

authors： Xue Y,Xie N,Lin Y,Xu J,Han Y,Wang S,Jiang H,Chi Z

更新日期：2011-04-06 00:00:00

abstract：:Antisense oligodeoxynucleotides (ODNs) are used for the selective inhibition of gene expression. Antisense ODNs are promising tools for the investigation of physiological implications of proteins in the central nervous system of rodents in vivo. We have previously demonstrated that a phosphorothioate antisense ODN to ...

journal_title：Brain research

authors： Karle J,Witt MR,Nielsen M

更新日期：1997-08-08 00:00:00

abstract：:We screened anti-Aβ1-42 antibodies from a human Alzheimer's disease (AD) specific single chain variable fragment (scFv) phage display library and assessed their effects in APP/PS1 transgenic mice. Reverse transcription-PCR was used to construct the scFv phage display library, and screening identified 11A5 as an anti-A...

journal_title：Brain research

authors： Wang J,Li N,Ma J,Gu Z,Yu L,Fu X,Liu X,Wang J

更新日期：2016-03-15 00:00:00

abstract：:With the aim of determining a possible role of the entorhinal cortex (EC) in the processing of olfactory information, its electrical activity was recorded during different types of odour sampling behaviour. The EC spontaneous field potentials (EEGs) were related to those recorded simultaneously from the more rostrally...

journal_title：Brain research

authors： Boeijinga PH,Lopes da Silva FH

更新日期：1989-01-30 00:00:00

abstract：:The median preoptic nucleus (MnPN) of the hypothalamus contains sleep-active neurons including sleep-active GABAergic neurons and is involved in the regulation of nonREM/REM sleep. The hypocretinergic (HCRT) neurons of the perifornical-lateral hypothalamic area (PF-LHA) and serotonergic (5-HT) neurons of the dorsal ra...

journal_title：Brain research

authors： Kumar S,Szymusiak R,Bashir T,Suntsova N,Rai S,McGinty D,Alam MN

更新日期：2008-10-09 00:00:00

abstract：:We have examined the influence of reducing conditions on the activity of group-I or -II metabotropic glutamate receptors. In cultured cerebellar granule cells or in hippocampal slices, the reducing agent dithiothreitol (DTT) inhibited the stimulation of polyphosphoinositide (PPI) hydrolysis elicited by group-I mGlu re...

journal_title：Brain research

authors： Copani A,Romano C,Di Giorgi Gerevini V,Nicosia A,Casabona G,Storto M,Mutel V,Nicoletti F

更新日期：2000-06-09 00:00:00

abstract：:The neuronal pathology caused by neonatal infection of rats with the PVC-211 murine leukemia virus (PVC-211 MuLV) and its underlying mechanisms are not well defined even though a loss of neurons and spongiform neurodegeneration has been reported to accompany the disease. Here we sought to identify sites of neurodegene...

journal_title：Brain research

authors： Xue QS,Yang C,Hoffman PM,Streit WJ

更新日期：2010-03-10 00:00:00

abstract：:Two D-amino acid substitution angiotensin analogues were compared against native angiotensin II (AII) and angiotensin III (AIII) for their resistance to brain tissue-induced degradation and for pressor potency when intracerebroventricularly (i.c.v.) infused in Sprague-Dawley rats. The in vitro results indicate that [D...

journal_title：Brain research

authors： Wright JW,Roberts KA,Cook VI,Murray CE,Sardinia MF,Harding JW

更新日期：1990-04-23 00:00:00

abstract：:Central administration of CRH results in endocrinological, cardiovascular, and behavioral effects that suggest stress or anxiety. Among these is a marked pressor response. Parenteral administration of CRH, however, results in hypotension. We used parenteral administration of antalarmin, a novel, small molecule CRH1 re...

journal_title：Brain research

authors： Briscoe RJ,Cabrera CL,Baird TJ,Rice KC,Woods JH

更新日期：2000-10-27 00:00:00

abstract：:Hypothalamic control of thermoregulatory evaporation has been examined in hydrated and dehydrated cats exposed to warm ambient temperatures. Reduction in evaporative cooling during dehydration is associated with increased hypothalamic temperature. Local thermal stimulation of the hypothalamus indicates that the thermo...

journal_title：Brain research

authors： Doris PA,Baker MA

更新日期：1981-02-09 00:00:00

abstract：:Application of horseradish peroxidase (HRP) to the proximal stump of the transected infraorbital (IO) nerve in the orbit was employed in normal adult rats to demonstrate the ganglionic representation of and brainstem innervation by the trigeminal (V) branch which supplies primarily the mystacial vibrissae. In the V ga...

journal_title：Brain research

authors： Jacquin MF,Rhoades RW

更新日期：1983-06-13 00:00:00

abstract：:The cat substantia nigra (SN) pars reticulata (SNR) has been observed electron microscopically after ibotenic acid injections into the caudate nucleus (Cd) and horseradish peroxidase injections into the nucleus tegmenti pedunculopontinus pars compacta (TPC). As a result, degenerating striatal terminals were found to m...

journal_title：Brain research

authors： Tokuno H,Moriizumi T,Kudo M,Kitao Y,Nakamura Y

更新日期：1989-04-17 00:00:00

abstract：:Ion-sensitive microelectrodes were used to study the behavior of extracellular ions in rat sciatic nerve during and following activity. Nerve stimulation produced increases in [K+]o that were dependent upon the frequency and duration of stimulation; no change in extracellular pH occurred with stimulation. Increases in...

journal_title：Brain research

authors： Hoppe D,Chvatal A,Kettenmann H,Orkand RK,Ransom BR

更新日期：1991-06-21 00:00:00

abstract：:To test the hypothesis that enkephalins, substance P, bradykinin and angiotensin II could act as neurohumoral modulators of hypothalamic function, these peptides (0.01-20 microgram) were injected into the general circulation of anesthetized rats, and changes in hypothalamo-neurohypophysial activity were determined by ...

journal_title：Brain research

authors： Baertschi AJ,Zingg HH,Dreifuss JJ

更新日期：1981-09-07 00:00:00

abstract：:In auditory speech processing, phonological stress functions as an attention holding cue, which facilitates detection of mispronunciations and phonetic deviants in strong syllables as compared to weak ones. Whereas silent reading involves activation of phonological information including word stress, it is not clear wh...

journal_title：Brain research

authors： Kriukova O,Mani N

更新日期：2016-04-01 00:00:00

abstract：:Unilateral destruction of the entorhinal area in the rat results in the proliferation of a pathway from the surviving contralateral entorhinal area to the fascia dentata denervated by the lesions (the crossed temporodentate pathway). The present study analyzes the point of entry of these reinnervating fibers into the ...

journal_title：Brain research

authors： Steward O

更新日期：1980-02-10 00:00:00

abstract：:Synaptosomes assemble an equatorial coil of microtubules during incubation at 37 degrees C. Stimulation of synaptosomes by veratridine or A23187 for 5 min results in disassembly of the microtubules. The role of microtubule disassembly in neurotransmitter release was investigated using the microtubule-stabilizing drug ...

journal_title：Brain research

authors： Burgoyne RD,Cumming R

更新日期：1983-11-28 00:00:00

abstract：:The receptor for advanced glycation end products (RAGE) is a multi-ligand member of the immunoglobulin superfamily of cell surface molecules. The RAGE-ligand interaction has a putative role in a range of chronic disorders and is also known to contribute to both inflammatory/degenerative processes as well as regenerati...

journal_title：Brain research

authors： Ma L,Carter RJ,Morton AJ,Nicholson LF

更新日期：2003-03-21 00:00:00

abstract：:The discriminative stimulus properties of ethanol are functionally regulated by ionotropic GABA(A) and NMDA receptors in specific limbic brain regions including the nucleus accumbens, amygdala, and hippocampus, as determined by microinjection studies. The purpose of the present work was to further investigate potentia...

journal_title：Brain research

authors： Besheer J,Schroeder JP,Stevenson RA,Hodge CW

更新日期：2008-09-26 00:00:00

abstract：:Glioblastoma stem cells (GSCs) are thought to contribute to the diffuse invasiveness of malignant gliomas. Emerging evidence supports a role for a disintegrin and metalloproteinase 17 (ADAM17) in proteolytic ectodomain shedding of several EGFR-binding ligands, which subsequently activate PI3K/AKT and MEK/ERK pathways ...

journal_title：Brain research

authors： Chen X,Chen L,Chen J,Hu W,Gao H,Xie B,Wang X,Yin Z,Li S,Wang X

更新日期：2013-11-13 00:00:00

abstract：:Chemotherapy-induced pain is the most common treatment-limiting complication encountered by cancer patients receiving taxane-, vinca alkaloid- or platin-based chemotherapy. Several lines of evidence indicate that activation of pro-inflammatory cascades involving the release of cytokines including tumor necrosis factor...

journal_title：Brain research

authors： Cata JP,Weng HR,Dougherty PM

更新日期：2008-09-10 00:00:00

abstract：:The main goal of the present study was to analyse the effects of (+/-)-huprine X ((+/-)-HX) and galantamine (GAL), with potentiating action on nicotinic receptors, and huperzine A (HPA), devoid of nicotinic activity, on [3H]-acetylcholine ([3H]-ACh) release in striatal slices of rat brain. All compounds are non-covale...

journal_title：Brain research

authors： Roman S,Badia A,Camps P,Muñoz-Torrero D,Clos MV

更新日期：2005-11-09 00:00:00

abstract：:In 22 squirrel monkeys (Saimiri sciureus) vocalization-eliciting electrodes were implanted into the amygdala and along the trajectory of the stria terminalis. Then, lesions were placed in the stria terminalis, its bed nucleus, the ventral amygdalofugal pathway and several di- and mesencephalic structures in order to f...

journal_title：Brain research

authors： Jürgens U

更新日期：1982-06-10 00:00:00

abstract：:Movement of fragmented DNA in dendrites of retinal neurons during the apoptotic cell death was investigated. The time-course of the movement of fragmented DNA in dendrites of retinal neurons undergoing apoptotic cell death induced by intravitreal N-methyl-d-aspartate (NMDA) injection were examined by in situ terminal ...

journal_title：Brain research

authors： Hara A,Niwa M,Kumada M,Kitaori N,Yamamoto T,Kozawa O,Mori H

更新日期：2004-05-08 00:00:00

abstract：:In this study, we have identified and characterized 5-HT3-like receptors in the rat medial prefrontal cortex (mPFc), an area with a moderate density of 5-HT3 binding sites, using the techniques of single unit recording and microiontophoresis. The microiontophoresis of the 5-HT3 receptor agonist 2-methylserotonin (2-Me...

journal_title：Brain research

authors： Ashby CR Jr,Minabe Y,Edwards E,Wang RY

更新日期：1991-06-07 00:00:00

abstract：:We have previously shown that the HSV-2 anti-apoptotic protein ICP10PK is delivered by the replication incompetent virus mutant DeltaRR and prevents kainic acid (KA)-induced epileptiform seizures and neuronal cell loss in the mouse and rat models of temporal lobe epilepsy. The present studies used DeltaRR and the ICP1...

journal_title：Brain research

authors： Gober MD,Laing JM,Thompson SM,Aurelian L

更新日期：2006-11-13 00:00:00