Heterogeneity of neurons in the crustacean X-organ as revealed by intracellular recording and injection of horseradish peroxidase.

abstract：:The pleiotropic cytokine tumor necrosis factor-alpha (TNFalpha) is implicated in the development of persistent pain through its actions in the periphery and in the central nervous system (CNS). Activation of the alpha(2)-adrenergic receptor is associated with modulation of pain, possibly through its autoregulatory eff...

journal_title：Brain research

authors： Covey WC,Ignatowski TA,Knight PR,Spengler RN

更新日期：2000-03-17 00:00:00

abstract：:Focal axonal swellings are characteristic of a wide range of neuropathies. Three neuron-specific monoclonal antibodies have been used to identify focal axonal swellings in the normal developing rat cerebellar cortex. Between 7 and 15 days postnatal, swellings are a common feature of the granular layer and white matter...

journal_title：Brain research

authors： Gravel C,Leclerc N,Plioplys A,Hawkes RB

更新日期：1986-01-22 00:00:00

abstract：:Chicks of 1-8 days after hatching were submitted to unilateral visual deprivation and, in both optic lobes, muscarinic receptors, labeled with L-[3H]quinuclidinyl benzylate [( 3H]L-QNB) and acetylcholinesterase (AChE) were assayed. Between 1 and 6 days the number of [3H]L-QNB binding sites was lower in the contralater...

journal_title：Brain research

authors： Jerusalinsky DA,De Robertis E

更新日期：1984-06-01 00:00:00

abstract：:Spatial learning and memory in rodents represent close equivalents of human episodic declarative memory, which is especially sensitive to cerebral aging, neurodegeneration, and various neuropsychiatric disorders. Many tests and protocols are available for use in laboratory rodents, but Morris water maze and radial-arm...

journal_title：Brain research

authors： Pooters T,Van der Jeugd A,Callaerts-Vegh Z,D'Hooge R

更新日期：2015-09-24 00:00:00

abstract：:Transforming growth factor beta (TGFbeta) modulates a variety of growth related functions following traumatic injury. The cellular response to TGFbeta is predominantly mediated through TGFbeta receptor I (TGFbetaRI) and receptor II (TGFbetaRII) on the cell surface and SMAD proteins intracellularly. We investigated the...

journal_title：Brain research

authors： Fee DB,Sewell DL,Andresen K,Jacques TJ,Piaskowski S,Barger BA,Hart MN,Fabry Z

更新日期：2004-06-25 00:00:00

abstract：:The present study provides evidence for the presence of an endogenous ligand for the phencyclidine (PCP) receptor of mammalian brain. Partially purified bovine hippocampal extracts potently and dose dependently inhibit binding to PCP receptors of [3H]N-(1-[2-thienyl]-cyclohexyl)piperidine (TCP), a highly potent and sp...

journal_title：Brain research

authors： Zukin SR,Zukin RS,Vale W,Rivier J,Nichtenhauser R,Snell LD,Johnson KM

更新日期：1987-07-21 00:00:00

abstract：:The response of two populations of neurones in the substantia nigra (nigro-striatal compacta neurones and reticulata neurones) to microelectrophoretically administered putative neurotransmitters and stimulation of the ipsilateral striatum has been investigated in anaesthetized rats. There were marked differences betwe...

journal_title：Brain research

authors： Collingridge GL,Davies J

更新日期：1981-05-18 00:00:00

abstract：:We have used the post-embedding immunogold labelling method using antibodies to gamma-aminobutyric acid (GABA) to obtain quantitative data on the distribution, frequency, postsynaptic targets and ultrastructural characteristics of GABA-immunoreactive (GABA-IR) boutons in the trigeminal motor nucleus of rats. We have a...

journal_title：Brain research

authors： Saha S,Appenteng K,Batten TF

更新日期：1991-10-04 00:00:00

abstract：:Ginseng is one of most extensively used traditional oriental medicines worldwide with beneficial efficacy on cognitive function disorders. Pharmacological researches on its active ingredient--ginsenoside Rg1 revealed that it can improve learning and memory potentially via modulating neurotransmission in the central ne...

journal_title：Brain research

authors： Liu ZJ,Zhao M,Zhang Y,Xue JF,Chen NH

更新日期：2010-05-28 00:00:00

abstract：:The 2009 influenza A(H1N1) pandemic led to a particularly high risk of morbidity and mortality among pregnant women. Therefore, inactivated influenza vaccines have been widely recommended for women in any period of gestation. Recent studies have shown that the peripheral adaptive immune system plays an important role ...

journal_title：Brain research

authors： Xia Y,Qi F,Zou J,Yao Z

更新日期：2014-12-10 00:00:00

abstract：:Recent neurocognitive studies of visual word recognition provide information about neuronal networks correlated with processes involved in lexical access and their time course (e.g., [Holcomb, Ph.J., Grainger J. and O'Rourke, T. (2002). An Electrophysiological Study of the Effects of Orthographic Neighborhood Size on ...

journal_title：Brain research

authors： Braun M,Jacobs AM,Hahne A,Ricker B,Hofmann M,Hutzler F

更新日期：2006-02-16 00:00:00

abstract：:The characteristics of synaptic transmission in whole embryonic avian sympathetic ganglia have been examined by intracellular recording. Neurons in lumbar paravertebral ganglia of chick embryos exhibit both fast nicotinic excitatory postsynaptic potentials (EPSPs) and non-cholinergic slow EPSPs. Fast nicotinic transmi...

journal_title：Brain research

authors： Dryer SE,Chiappinelli VA

更新日期：1985-09-01 00:00:00

abstract：:One hundred and four visual units of the (ventral) lateral geniculate nucleus (GL) of chicks (Gallus domesticus) were studied with extracellular microelectrodes. Most were extremely responsive to moving targets even at low speeds (0.1 degrees/sec). They were classified as follows. (1) movement-sensitive units with uni...

journal_title：Brain research

authors： Pateromichelakis S

更新日期：1979-05-11 00:00:00

abstract：:Increased and sustained central delivery of L-dihydroxyphenylalanine (L-DOPA) is a desirable therapeutic strategy in Parkinson's disease. We investigated the effects of peripheral catechol-O-methyltransferase (COMT) inhibition, by the non-toxic drug nitecapone on the metabolism of 6-[18F]fluoro-L-dihydroxyphenylalanin...

journal_title：Brain research

authors： Miletich RS,Comi G,Bankiewicz K,Plunkett R,Adams R,Di Chiro G,Kopin IJ

更新日期：1993-10-29 00:00:00

abstract：:The effect of an 8% casein and a control 25% casein diet on the granule cells in the dorsal blade of the dentate gyrus of the rat hippocampal formation was studied at 30, 90 and 220 days of age. Female rats were fed either an 8% or 25% casein diet 5 weeks prior to conception and the litters were maintained on these re...

journal_title：Brain research

authors： Cintra L,Díaz-Cintra S,Galván A,Kemper T,Morgane PJ

更新日期：1990-11-05 00:00:00

abstract：:Proliferating astrocytes and proliferating neuroblasts have been observed in the subgranular zone (SGZ) of the dentate gyrus (DG) in the hippocampus of adult rats under normal conditions. However, whether these proliferating cells are stimulated by running has not been determined. Using immunohistochemical techniques,...

journal_title：Brain research

authors： Uda M,Ishido M,Kami K,Masuhara M

更新日期：2006-08-09 00:00:00

abstract：:The effect of anesthesia upon the functional outcome after experimental spinal cord injury (SCI) was studied in 221 rats subjected to graded weight drop contusion in the thoracic cord. Neurologic function was assessed in a blinded fashion for one week after injury using a modification of the method of Tarlov. The post...

journal_title：Brain research

authors： Salzman SK,Mendez AA,Sabato S,Lee WA,Ingersoll EB,Choi IH,Fonseca AS,Agresta CA,Freeman GM

更新日期：1990-06-25 00:00:00

abstract：:In this study the laminar localization of binding sites for the muscarinic radioligand [3H]3-quinuclidinylbenzilate was studied in somatosensory cortex of infant rat. Using light autoradiographic techniques, [3H]QNB was found to be concentrated in layer IV. Atropine-pretreated pups showed evenly dispersed, nonspecific...

journal_title：Brain research

authors： Kristt DA,Kasper EK

更新日期：1983-06-01 00:00:00

abstract：:The present study investigated the effects of systemic administration of dexmedetomidine, a selective alpha2 adrenergic receptor (alpha2AR) agonist, and gabapentin either alone or in combination on thermal hyperalgesia evoked by ankle joint inflammation. Monoarthritis of rat ankle joint was induced by an intra-articul...

journal_title：Brain research

authors： Zhang WS,Xu H,Xu B,Sun S,Deng XM,Zhang YQ

更新日期：2009-04-06 00:00:00

abstract：:The effects of lesions in the pars compacta of the substantia nigra of 4-week-old spontaneously hypertensive rats (SHR) and normotensive Wistar-Kyoto rats (WKY) were studied on (a) changes in blood pressure during a period of 6 weeks following lesioning, and (b) dopamine and metabolite concentrations in the caudate nu...

journal_title：Brain research

authors： Linthorst AC,van Giersbergen PL,Gras M,Versteeg DH,de Jong W

更新日期：1994-03-14 00:00:00

abstract：:It has been reported that training affects motor responses evoked electrically from the dorsomedial frontal cortex (DMFC). Once a monkey had been trained to generate visually-guided saccadic eye movements of a particular size and direction, electrical stimulation of the DMFC elicited saccades of only that size and dir...

journal_title：Brain research

authors： Tehovnik EJ,Slocum WM

更新日期：2000-09-15 00:00:00

abstract：:Glycine is thought to be a major inhibitory neurotransmitter in the mammalian CNS. Two types of physiologically identified interneurons, Renshaw cells and Ia inhibitory interneurons, were intracellularly stained with horseradish peroxidase, and their axon terminals were studied at the electron microscopic level. Post-...

journal_title：Brain research

authors： Fyffe RE

更新日期：1991-04-26 00:00:00

abstract：:In chloralose-urethane anaesthetized cats and in one unanesthetized decerebrate cat, the possibility of a baroreceptor pathway exerting an inhibitory effect directly on the sympathetic preganglionic neurone (SPN) was examined. Stimulation of excitatory points in the brain stem and spinal cord evoked responses in T3 wh...

journal_title：Brain research

authors： Coote JH,Macleod VH,Fleetwood-Walker SM,Gilbey MP

更新日期：1981-09-07 00:00:00

abstract：:5-Hydroxytryptamine (5-HT)-like immunoreactive neurones were studied during the development of myenteric plexus explant cultures from the guinea-pig taenia coli over a period of 3 weeks in vitro, using immunofluorescence histochemistry. Brightly fluorescent 5-HT-like immunoreactive neuronal cell bodies and fibres were...

journal_title：Brain research

authors： Saffrey MJ,Legay C,Burnstock G

更新日期：1984-06-18 00:00:00

abstract：:Dexmedetomidine (Dex) has the neuroprotective effect on cerebral ischemia-reperfusion injury (CIRI). But the mechanism is not yet clear. In this study, we established a model of middle cerebral artery occlusion (MCAO) and treated primary cortical neurons with oxygen glucose deprivation (OGD), followed by Dex treatment...

journal_title：Brain research

authors： Liu C,Fu Q,Mu R,Wang F,Zhou C,Zhang L,Yu B,Zhang Y,Fang T,Tian F

更新日期：2018-12-15 00:00:00

abstract：:In order to study the effects of treatment with monosodium glutamate (MSG) during the neonatal period on the intrinsic circadian timekeeping system in rats, the locomotor activity of blinded MSG-treated and control (saline-treated) rats was analyzed with power spectral analysis and cross-correlation. In contrast to a ...

journal_title：Brain research

authors： Miyabo S,Yamamura I,Ooya E,Aoyagi N,Horikawa Y,Hayashi S

更新日期：1985-07-29 00:00:00

abstract：:Visuomotor behavior and pattern discrimination were studied in a group of cats raised with one eye closed by eyelid suturing 7-10 days after birth. At the age of 8-10 months the animals were forced to use their deprived eye by reversal of eye closure (closing the normal eye and opening the deprived one). Visuomotor be...

journal_title：Brain research

authors： Hof-Van Duin JV

更新日期：1976-07-30 00:00:00

abstract：:The brainstem nucleus, locus coeruleus (LC), is the major, if not the sole, source of noradrenergic (NE) innervation of the telencephalon. It is generally held that LC neurons project diffusely to the entire neuroaxis and this had been the basis for theories that postulate 'general' functions (sleep, attention, learni...

journal_title：Brain research

authors： Shipley MT,Halloran FJ,de la Torre J

更新日期：1985-03-11 00:00:00

abstract：:The object of this study was to quantify and compare the degree of control monkeys may assert over firing patterns of normal and epileptic neurons. Thirty-seven epileptic and 70 normal neurons were studied in detail. The operant task was for the monkey to generate specified consecutive interspike intervals (ISI). The ...

journal_title：Brain research

authors： Wyler AR,Finch CA,Burchiel KJ

更新日期：1978-08-04 00:00:00

abstract：:The temporal and spatial distribution of immunocytochemically identified reactive astrocytes is described following a cerebral stab wound in adult rats. Different patterns of reactivity were observed in the cerebral cortex, the corpus callosum and the deep structures of the hemisphere. In the cerebral cortex, the zone...

journal_title：Brain research

authors： Mathewson AJ,Berry M

更新日期：1985-02-18 00:00:00