Abstract:
:The occurrence of unmyelinated axons was examined ultrastructurally in rat molar and incisor root pulps of normal rats, of neonatally capsaicin-treated rats, of rats subjected to neonatal capsaicin treatment followed by resection of the superior cervical ganglion and of sympathectomized but otherwise normal rats. Following capsaicin treatment the occurrence of unmyelinated pulpal axons was slightly subnormal. Sympathectomy was largely without effect on the population of unmyelinated axons in tooth pulps of capsaicin-treated rats. In normal rats the proportion of unmyelinated axons in molar pulps was not altered by sympathectomy but it caused a slight decrease in the number of unmyelinated incisor pulpal axons. These findings support the view that most of the unmyelinated axons in rat molar and incisor pulps are sensory, that the parent neurons of these axons differ from nociceptive neurons at other sites by being largely resistant to neonatal capsaicin treatment and that very few unmyelinated tooth pulp axons represent postganglionic efferents.
journal_name
Brain Resjournal_title
Brain researchauthors
Fried K,Aldskogius H,Hildebrand Cdoi
10.1016/0006-8993(88)90533-1subject
Has Abstractpub_date
1988-10-25 00:00:00pages
118-23issue
1eissn
0006-8993issn
1872-6240pii
0006-8993(88)90533-1journal_volume
463pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract::The distribution of neural elements immunoreactive to several peptides with a possible messenger role was studied in the lamprey spinal cord by using an indirect immunofluorescence method. Different patterns of immunoreactive (IR) fibers were detected by antisera raised against cholecystokinin, metorphamide, bombesin,...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(87)90392-1
更新日期:1987-04-07 00:00:00
abstract::The trisomy-16 mouse is considered to be a model of human trisomy-21 (Down syndrome). We have examined the electrical membrane properties of cultured dorsal root ganglion (DRG) neurons from normal and trisomy-16 fetuses. Trisomy-16 neurons had significantly accelerated rates of action potential depolarization and repo...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(89)90678-1
更新日期:1989-04-17 00:00:00
abstract::Tyrosine kinase B (TrkB) levels in the adult guinea pig cochlear nucleus (CN) were determined from Western blots for up to 60 days after unilateral cochlear ablation (UCA). Compared to TrkB levels on the intact side, those on the lesioned side were elevated in the anteroventral CN (AVCN) at 7 and 60 days and in the po...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(02)03679-x
更新日期:2002-12-13 00:00:00
abstract::Transthyretin (TTR) is mainly expressed in the liver and choroid plexus of the brain. The majority of familial amyloidotic polyneuropathy cases are caused by a mutant TTR gene. The origin of the TTR deposited in the peripheral nervous system is unknown. We studied the expression of TTR in the peripheral nerves of norm...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2010.06.017
更新日期:2010-08-12 00:00:00
abstract::Docosahexaenoic acid (DHA), an omega-3 polyunsaturated fatty acid, is an essential component of membrane phosphatides and has been implicated in cognitive functions. Low levels of circulating or brain DHA are associated with various neurocognitive disorders including Alzheimer's disease (AD), while laboratory animals,...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2007.08.089
更新日期:2007-11-28 00:00:00
abstract::The regulatory role of endothelins in cerebral microvessels was investigated in a recently developed model system which allows the study of small cerebral vessels in their normal microenvironment. Using brain slices of the rat neocortex, it was shown that the isopeptide endothelin-3 (ET-3) had no effect on cerebral mi...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(09)90024-5
更新日期:1994-09-26 00:00:00
abstract::Expertise offers a unique insight into how our brain functions. The purpose of this experiment was to determine if motor system activity and functional connectivity between the cognitive system and sensorimotor system is differentially modulated by an individual's level of expertise. This goal was achieved through the...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2013.09.048
更新日期:2013-12-02 00:00:00
abstract::The possible interference of nitric oxide (NO) in glucose metabolism was studied in activated astrocytes. Lipopolysaccharide (LPS) treatment triggered a NO-mediated increase in glucose consumption and lactate production, suggesting an enhanced rate of glycolysis. Active glycogen synthesis was also observed after LPS t...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(02)02877-9
更新日期:2002-07-26 00:00:00
abstract::A major mesolimbic projection towards the hippocampal formation (HF) has been extensively described, but no clear evidence of its dopaminergic content has been demonstrated. In order to evaluate the percentage of dopaminergic (DA) cells of ventral tegmental area (VTA-A10) and adjacent substantia nigra (SN-A9) projecti...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(94)90512-6
更新日期:1994-12-30 00:00:00
abstract::The effect of an extended program of perforant path or amygdala kindling on paired-pulse suppression in the dentate gyrus was studied in male hooded rats. Repeated kindling stimulations were delivered twice or three times daily until either 300 stimuli had been delivered or generalized convulsions had been observed to...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(94)01277-o
更新日期:1995-01-23 00:00:00
abstract::Rabbits passively oscillated in the horizontal plane with a free hand tended to stabilize their head in space (re: earth-fixed surroundings) by moving the head on the trunk (neck angular deviation, NAD) opposite the passively imposed body rotation. The gain (NAD/body rotation) of head stabilization varied from 0.0 to ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(81)90346-2
更新日期:1981-02-02 00:00:00
abstract::This study shows that the axons of some raphespinal sympathoinhibitory neurons projecting to the third thoracic spinal segment emit branches in the third-fourth cervical spinal segments of cats. This was demonstrated by using time-controlled collision of neuronal action potentials initiated by stimuli applied at these...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(88)91417-5
更新日期:1988-02-16 00:00:00
abstract::Dopamine (DA) and noradrenaline (NA) extracellular levels have been measured by microdialysis in the medial frontal cortex (MFC), nucleus accumbens (NAc) and caudate-putamen (CP) under baseline conditions in awake and halothane-anaesthetized rats, and after application of three types of stimuli which are likely to act...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(92)90711-h
更新日期:1992-05-29 00:00:00
abstract::William James noted that memories could persist from minutes to weeks. This essay attempts to explain this variation by situating the explanation in the biochemistry of dendritic spines. Two outcomes are critical to generate the synaptic basis of memory: (1) the actin cytoskeleton in the spine must be degraded to perm...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2014.12.009
更新日期:2015-09-24 00:00:00
abstract::The characteristics of dopamine adenylate cyclase in the rat striatum were first studied on homogenates of fresh tissues. In the assay conditions used, dopamine (10(-4) M) stimulated the enzyme activity by 250%. This effect was completely blocked by fluphenazine (10(-5) M; Ki=9X10(-9) M) and by phentolamine (10(-5) M;...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(76)90228-6
更新日期:1976-05-07 00:00:00
abstract::The effects of postnatal thyroidectomy (on day 8 after birth) and 131I treatment (on day 10) on the development of the vomeronasal organ (VO) has been studied In the rat. Thyroidectomized rats showed decrements in the overall VO volume, volume of the neurosensorial epithelium, neuronal population and nuclear size of n...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0165-3806(82)90159-6
更新日期:1982-10-01 00:00:00
abstract::A study was undertaken of the possible relationship of the binding affinity of a series of anticholinergic psychotomimetic drugs to their psychopharmacological and anticholinergic effects. Binding was measured to brain homogenates and nerve endings using [3H]quinuclidinyl benzilate (QB), a highly potent psychotomimeti...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(77)90889-7
更新日期:1977-03-25 00:00:00
abstract:BACKGROUND:Perinatal brain injury in preterm infants is a major cause of neurological handicap. The role of the neurotrophin receptor p75 (p75(NTR)) in the pathogenesis and repair of neonatal excitotoxic brain injury is unknown. Depending on a complex interplay of neurotrophin signalling, p75(NTR) can, in addition to i...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2010.07.095
更新日期:2010-10-08 00:00:00
abstract::Earlier studies in this laboratory have shown that partial serotonergic (5-HT) deafferentation from the hippocampus induced a homotypic sprouting. The 5-HT-denervated hippocampus was further found to be a favorable environment for the growth of grafted 5-HT, but not for norepinephrinergic neurons. In the current study...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(90)90286-k
更新日期:1990-01-22 00:00:00
abstract::Cerebrovascular carbon dioxide (CO2) reactivity is an important hemodynamic index in cerebrovascular disease. In the present study T2*-weighted magnetic resonance image (T2* WI) was evaluated as a non-invasive method to investigate changes in CO2 reactivity. Fourteen rats were subjected to permanent or, 30 and 90 min ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/S0006-8993(96)01079-7
更新日期:1997-01-09 00:00:00
abstract::Facial allodynia is a migraine symptom that is generally considered to represent a pivotal point in migraine progression. Treatment before development of facial allodynia tends to be more successful than treatment afterwards. As such, understanding the underlying mechanisms of facial allodynia may lead to a better und...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2017.03.011
更新日期:2017-06-01 00:00:00
abstract::The dorsolateral funiculus (DLF) spinal pathway has previously been identified as a major pathway involved in descending modulation of pain. While bilateral lesions of the DLF attenuated systemic morphine analgesia as measured by the tail-flick test, they failed to attenuate analgesia as measured by the formalin test....
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(85)90582-7
更新日期:1985-05-13 00:00:00
abstract::The suspected functional role of dendritic spines as loci of neuronal plasticity (possibly memory and learning) is greatly enriched when active membrane properties are assumed at the spine head. Computations with reasonable electrical and structural parameter values (corresponding to an optimal range for spine stem re...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(85)90333-6
更新日期:1985-01-28 00:00:00
abstract::Traumatic brain injury (TBI) in humans typically produces neurological suppression and a longer lasting impairment of memory clinically defined as post-traumatic amnesia. An animal model that reliably reproduces the physiological changes associated with TBI was used to assess the memory deficits following brain injury...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(93)91014-j
更新日期:1993-06-18 00:00:00
abstract::A decline in the magnitude of the summated responses evoked by taste solutions began about 1 h following IXth nerve transection. In 41 IXth nerves transected at different lengths we found a linear relationship between the length of the IXth nerve stump remaining attached to the tongue and the time for the taste respon...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)91331-1
更新日期:1980-07-21 00:00:00
abstract::The zebrafish, Danio rerio, has become an important model species for examining olfactory system structure and function, yet little is known about developmental changes in olfactory bulb morphology from embryo to adult. The present study examined both normal growth and the effects of deafferentation on the bulb from h...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(99)02412-9
更新日期:2000-02-21 00:00:00
abstract::We measured the uptake of a radiolabeled analogue of glucose ([3H]FDG) into muscles during treadmill walking so as to determine whether sensory deafferentation of a limb affects the muscles' metabolic response to the exercise. The muscles on the deafferented side took up less tracer than those in the intact side with ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(85)91526-4
更新日期:1985-02-18 00:00:00
abstract::The following data were obtained from microelectrode exploration of rabbit auditory cortex (AC). (1) Location of AC--Major portions of the rabbit's right hemisphere were stereotaxically mapped for auditory responsive and non-responsive regions. Auditory responsive regions were found to lie behind the rhinal sulcus, ex...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(81)91194-x
更新日期:1981-06-15 00:00:00
abstract::Previous research has suggested the potential involvement of the hypothalamic-pituitary-adrenal (HPA) axis in psychostimulant reinforcement. In particular, we have found significant correlations between electric footshock-induced increases in plasma corticosterone and the acquisition, or lack thereof, of intravenous c...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(96)00206-5
更新日期:1996-05-25 00:00:00
abstract::Cerebral venous thrombosis (CVT) is a rare form of cerebral stroke that causes a variety of symptoms, ranging from mild headache to severe morbidity or death in the more severe forms. The use of anti-coagulant or thrombolytic agents is the classical treatment for CVT. However, the development of new therapies for the ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2018.06.029
更新日期:2018-11-15 00:00:00