Abstract：
:Myelin of several Caudata (Urodela) species appears to be unique in the fact that it lacks hydroxycerebrosides and hydroxysulfatides although it contains their non-hydroxy counterparts. Comparison of the nerve conduction velocities in the Urodeles Necturus (salamander) and Notophthalmus (newt) with that in a reptile, Anolis (chameleon) which contains hydroxycerebrosides and -sulfatides indicated that the values were significantly reduced in the urodeles. Furthermore, urodele myelin thickness remained uniformly the same regardless of the size of the nerve fiber. Despite these differences the myelins appeared structurally similar. Electron microscopic and X-ray diffraction studies did not disclose any structural difference between the two orders. A teased fiber technique established that the ratio of internodal distance and fiber diameter in urodele nerves was essentially similar to that in Anolis. These findings suggest that the absence of hydroxycerebroside and -sulfatide may be related to the reduction in nerve conduction velocity and unusual myelin thickness in the urodele nervous system.
journal_name
Brain Resjournal_title
Brain researchauthors
Ki PF,Kishimoto Y,Lattman EE,Stanley EF,Griffin JWdoi
10.1016/0006-8993(85)90831-5subject
Has Abstractpub_date
1985-10-14 00:00:00pages
19-24issue
1eissn
0006-8993issn
1872-6240pii
0006-8993(85)90831-5journal_volume
345pub_type
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