Abstract：
:The two inbred strains of mice C57BL/6 and DBA/2 are characterized by a different behavioral reactivity to cholinergic agents during development. The present experiment revealed that the strain-dependent differences in cholinergic-mediated analgesia during development disappeared during adult life. In fact, oxotremorine administration (0.0025 and 0.005 mg/kg) exerted the same analgesic effect in both strains at 6 months of age, in contrast with the finding of the lack of any effect of the drug in C57 mice at two months of age in comparison with DBA.
journal_name
Brain Resjournal_title
Brain researchauthors
Fagioli S,Consorti D,Pavone Fdoi
10.1016/0006-8993(90)90743-usubject
Has Abstractpub_date
1990-02-26 00:00:00pages
150-3issue
1eissn
0006-8993issn
1872-6240pii
0006-8993(90)90743-Ujournal_volume
510pub_type
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