Spinal cord projections from the medial cerebellar nucleus in tree shrew (Tupaia glis).

Abstract:

:Electrolytic lesions were placed in the medial cerebellar nucleus in tree shrews (Tupaia glis) or in fibers issuing from this nucleus. Brains and spinal cords were processed according to Fink-Heimer procedure following survival times of 2-7 days. In control animals lesions were placed in the cerebellar cortex and, in one case, in the olfactory bulb. Degenerating fibers were seen entering the cervical spinal cord and continuing to thoracic and lumbar levels. The projection is relatively profuse in the cervical cord, becoming sparse as the fibers proceed to more caudal levels. Fibers run in the lateral funiculus, predominantly contralateral to the lesion. Some fibers are observed to travel directly through the intermediate gray matter of the spinal cord. Preterminal degeneration is seen primarily in the intermediate gray of the spinal cord. Results are discussed in relation to typical locomotor behavior of tree shrew.

journal_name

Brain Res

journal_title

Brain research

authors

Ware CB,Mufson EJ

doi

10.1016/0006-8993(79)91044-8

subject

Has Abstract

pub_date

1979-08-10 00:00:00

pages

383-400

issue

3

eissn

0006-8993

issn

1872-6240

pii

0006-8993(79)91044-8

journal_volume

171

pub_type

杂志文章
  • Separation of different interictal discharge patterns in acute experimentally induced epileptic foci of the rat in vivo.

    abstract::Epileptic discharge patterns in an acute experimental model of epilepsy were analyzed. Epileptic foci were induced by epicortical application of penicillin on the rat motor cortex in vivo. Patterns with regular 1/s discharges, patterns with irregular discharges of about 0.5/s as well as compound patterns comprising di...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(93)90221-8

    authors: Dorn T,Witte OW

    更新日期:1993-07-09 00:00:00

  • Protective effect of stellate ganglion block on delayed cerebral vasospasm in an experimental rat model of subarachnoid hemorrhage.

    abstract::Stellate ganglion block (SGB) is a blockade of sympathetic ganglia innervating the head and neck, and is known to function through vasodilation of the target region. However, the effectiveness of SGB in relieving cerebral vasospasm (CVS) through dilation of intracerebral vessels has not been evaluated. The aim of the ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2014.08.012

    authors: Hu N,Wu Y,Chen BZ,Han JF,Zhou MT

    更新日期:2014-10-17 00:00:00

  • The proportion of neurons in the rat neostriatum that project to the substantia nigra demonstrated using horseradish peroxidase conjugated with wheatgerm agglutinin.

    abstract::Following the injection of small volumes of horseradish peroxidase conjugated with wheatgerm agglutinin into the substantia nigra of the rat, a high proportion of the total neuronal population in parts of the ipsilateral neostriatum was retrogradely labelled with horseradish peroxidase. Quantitative estimates in 1-mic...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(81)91222-1

    authors: Bolam JP,Powell JF,Totterdell S,Smith AD

    更新日期:1981-09-14 00:00:00

  • The effects of aging on hippocampal and cortical projections of the forebrain cholinergic system.

    abstract::It has been proposed that disruption of cholinergic input to the hippocampus and cortex contributes to the learning and memory deficits associated with aging. The data reviewed here, however, suggest that the oft-stated generalization that normal aging is characterized by disruption of cholinergic input to the hippoca...

    journal_title:Brain research

    pub_type: 杂志文章,评审

    doi:10.1016/0165-0173(87)90007-5

    authors: Decker MW

    更新日期:1987-11-01 00:00:00

  • Theophylline-induced respiratory recovery following cervical spinal cord hemisection is augmented by serotonin 2 receptor stimulation.

    abstract::Cervical spinal cord hemisection leads to a disruption of bulbospinal innervation of phrenic motoneurons resulting in paralysis of the ipsilateral hemidiaphragm. We have previously demonstrated separate therapeutic roles for theophylline, and more recently serotonin (5-HT) as modulators to phrenic nerve motor recovery...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(02)03097-4

    authors: Basura GJ,Nantwi KD,Goshgarian HG

    更新日期:2002-11-22 00:00:00

  • The acoustic startle reflex in Sprague-Dawley rats is altered by permanent middle cerebral artery occlusion.

    abstract::The startle reflex is an unconditioned, quantifiable behavior used to study sensory modalities. We examined whether the acoustic startle reflex (ASR) was sensitive to lesions induced by focal cerebral ischemia. Sprague-Dawley rats were pre-screened for startle reflex responses 3-6 days prior to surgery and there were ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2004.10.065

    authors: Maynard KI,Sukoff SJ,Ji Z,Wettstein JG,Black MD

    更新日期:2005-01-25 00:00:00

  • Effects of repeated injections of the neurotensin analog NT69L on dopamine release and uptake in rat striatum in vitro.

    abstract::The effect of five daily intraperitoneal (i.p.) injections of NT69L on in vitro dopamine release, uptake, and [(3)H]NT binding in rat striatal tissue was investigated. NT69L perfusion increased K(+)-evoked and electrically evoked [(3)H]DA release. NT receptor-1 antagonist SR48692 inhibited the stimulatory effect of NT...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2004.07.069

    authors: Wang R,Boules M,Tiner W,Richelson E

    更新日期:2004-10-29 00:00:00

  • Efferent discharge patterns in the ciliary nerve of rabbits and the pupillary light reflex.

    abstract::Unitary discharges in the efferent ciliary nerves were studied in cervical sympathectomized rabbits. In all, 279 units were recorded and categorized, except 7 units, into the following 3 types from their responses to photic and other stimuli, i.e. type A (170 units), type B (42 units) and type C (60 units). Type A uni...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(80)90254-1

    authors: Inoue T

    更新日期:1980-03-17 00:00:00

  • The persistence of a normally transient cerebrocerebellar pathway in the cat.

    abstract::A direct, although transient, projection from the sensorimotor cortex to the cerebellum has been described previously in the neonatal kitten. The present report demonstrates that this pathway can be induced to persist into juvenile stages of the cat by partially denervating the deep cerebellar nuclei. Most of the cere...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(86)80021-x

    authors: Panneton WM

    更新日期:1986-11-01 00:00:00

  • The vermal projection of spinocerebellar tracts arising from lower cervical segments in the cat: an anterograde WGA-HRP study.

    abstract::Following injections of WGA-HRP into lower cervical segments, the distribution of anterograde labeled terminals of spinocerebellar fibers was examined in the vermal cortex of the cat. The labeled terminals were seen in sublobules Ib to VIc, VIIb, VIIIa and VIIIb, and lobule IX. They were present mainly in the medial p...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(85)91261-2

    authors: Matsushita M,Ikeda M,Tanami T

    更新日期:1985-12-23 00:00:00

  • Effects of nucleus accumbens amphetamine on lateral hypothalamic brain stimulation reward.

    abstract::The effects of amphetamine were examined in a brain stimulation reward paradigm in which response rate was measured across a range of stimulation frequencies. Both low (0.0625 and 0.125 mg/kg) and high (1.0, 2.0 and 4.0 mg/kg) doses of systemic amphetamine decreased the stimulation frequency needed to sustain low rate...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(88)90653-1

    authors: Colle LM,Wise RA

    更新日期:1988-09-06 00:00:00

  • Mu- and delta-opioid receptor binding peaks and kappa-homogeneity in the molecular layers of rat hippocampal formation.

    abstract::The sublaminar binding profiles of (D-Ala-NMe-Phe-Gly-ol)-enkephalin (DAGO), (2-D-penicillamine), 5-D-penicillamine)-enkephalin (DPDPE), and dynorphin A(1-8) (DYN) were studied in the CA1 subfield and dentate gyrus of rat hippocampal formation. Binding was assayed on cryomicrotome sections using coverslip autoradiogra...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(88)91215-2

    authors: Plager MD,Vogt BA

    更新日期:1988-09-13 00:00:00

  • The development and restriction of the ipsilateral retinofugal projection in the chick.

    abstract::Although it is generally believed that the central projections of the retina in birds are entirely crossed, using wheat germ agglutinin-conjugated horseradish peroxidase (WGA-HRP) as an anterograde tracer, we have found that in normal posthatched chicks there is a small ipsilateral retinofugal projection to the dience...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0165-3806(83)90124-4

    authors: O'Leary DM,Gerfen CR,Cowan WM

    更新日期:1983-10-01 00:00:00

  • Cerebrospinal fluid (CSF) and brain monoamine metabolites in the developing rat pup.

    abstract::Concentrations of the neurotransmitters, serotonin (5-HT), dopamine (DA), and norepinephrine (NE) were measured in the developing rat brain at 12, 19, 26 and 42 days of age. The amino acid precursors, tryptophan (TRP) and tyrosine (TYR) were measured along with the 5-HT and DA metabolites, 5-hydroxyindoleacetic acid (...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0165-3806(85)90146-4

    authors: Shaywitz BA,Anderson GM,Cohen DJ

    更新日期:1985-01-01 00:00:00

  • Is the androgen-dependent increase in preoptic estradiol-17 beta formation due to aromatase induction?

    abstract::Aromatization of testosterone in the preoptic area of the male ring dove is required for the expression of specific estrogen-sensitive sexual behavior. Estradiol metabolism and/or binding of the aromatization product(s) to the preoptic estrogen receptors (ER) could interfere with the apparent increase in estradiol for...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(89)90203-5

    authors: Steimer T,Hutchison JB

    更新日期:1989-02-20 00:00:00

  • The effect of acute citalopram on extracellular 5-HT levels is not augmented by lithium: an in vivo microdialysis study.

    abstract::A substantial number of patients do not respond sufficiently to antidepressant drugs and are therefore often co-medicated with lithium as an augmentative strategy. Since lithium has been demonstrated to affect 5-HT neurotransmission, we examined the effect of acute and subchronic lithium on 5-HT levels after a challen...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(00)02461-6

    authors: Wegener G,Linnet K,Rosenberg R,Mørk A

    更新日期:2000-07-21 00:00:00

  • Sexual maturation modifies the GABAergic control of gonadotrophin secretion in female rats.

    abstract::Administration of aminooxyacetic acid, (an inhibitor of gamma-aminobutyric acid (GABA)-transaminase which enhances the hypothalamic GABA content) increased luteinizing hormone (LH) and follicle stimulating hormone (FSH) levels in prepubertal rats (16 days of age), and decreased the levels of these pituitary hormones i...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(91)91508-x

    authors: Moguilevsky JA,Carbone S,Szwarcfarb B,Rondina D

    更新日期:1991-11-01 00:00:00

  • Interactions of ibogaine and D-amphetamine: in vivo microdialysis and motor behavior in rats.

    abstract::Ibogaine, an indolalkylamine, has been proposed for use in treating stimulant addiction. In the present study we sought to determine if ibogaine had any effects on the neurochemical and motor changes induced by D-amphetamine that would substantiate the anti-addictive claim. Ibogaine (40 mg/kg, i.p.) injected 19 h prio...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(92)90745-u

    authors: Maisonneuve IM,Keller RW Jr,Glick SD

    更新日期:1992-05-01 00:00:00

  • Synchronous firing dynamics in a heterogeneous neurosecretory-cell population in an insect.

    abstract::Five pairs of neurosecretory cells in the subesophageal ganglion of the silkmoth Bombyx mori discharge action potentials in (near) synchrony to release a pheromone biosynthesis-activating neuropeptide (PBAN). Waveforms of compound action potentials recorded extracellularly from axonal tracts were analyzed to determine...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(01)03349-2

    authors: Ichikawa T

    更新日期:2002-03-08 00:00:00

  • Neuropeptide Y-immunoreactive neurons in the striatum of cat and monkey: morphological characteristics, intrinsic organization and co-localization with somatostatin.

    abstract::A detailed study of the distribution of neuropeptide Y (NPY) in the striatum of squirrel monkey (Saimiri sciureus) and cat was undertaken by means of indirect immunofluorescence and peroxidase-antiperoxidase (PAP) methods. In monkey, the NPY-immunoreactivity is homogeneously distributed along the entire extent of the ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(86)91131-5

    authors: Smith Y,Parent A

    更新日期:1986-05-07 00:00:00

  • Differential role of histamine in mediating stress-induced changes in central dopaminergic neuronal activity in the rat.

    abstract::The role of histamine in mediating restraint stress-induced alterations in dopaminergic neuronal activity and alpha-melanocyte-stimulating hormone (alpha MSH) secretion was evaluated in male rats. Dopaminergic neuronal activity was estimated by measuring concentrations of the dopamine metabolite 3,4-dihydroxyphenylace...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(94)90399-9

    authors: Fleckenstein AE,Lookingland KJ,Moore KE

    更新日期:1994-08-08 00:00:00

  • Affective picture perception: emotion, context, and the late positive potential.

    abstract::Event-related potentials (ERP) were measured when pleasant, neutral or unpleasant pictures were presented in the context of similarly valenced stimuli, and compared to ERPs elicited when the same pictures were viewed in an intermixed context. An early ERP component (150-300 ms) measured over occipital and fronto-centr...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2007.10.072

    authors: Pastor MC,Bradley MM,Löw A,Versace F,Moltó J,Lang PJ

    更新日期:2008-01-16 00:00:00

  • Limbic seizures originating in the olfactory bulb: an electro-behavioral and glucose metabolism study.

    abstract::We studied seizures which were induced by a microinjection of kainic acid (KA) into the unilateral olfactory bulb (OB) in the rats. The first epileptiform discharge appeared in the OB, was then propagated to the amygdala and the hippocampus unilaterally, and finally propagated to the unilateral sensori-motor cortex. C...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(95)00626-2

    authors: Araki T,Kato M,Kobayashi T

    更新日期:1995-09-25 00:00:00

  • Toll-like receptor 4 is involved in ischemic tolerance of postconditioning in hippocampus of tree shrews to thrombotic cerebral ischemia.

    abstract:BACKGROUND:Toll-like receptor 4 (TLR4) is an important mediator of the innate immune response. It significantly contributes to neuroinflammation and may be involved in ischemic tolerance. It is unknown how cerebral ischemia in the cortex and postconditioning might affect inflammatory reactions in the hippocampus or whe...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2011.02.005

    authors: Feng R,Li S,Li F

    更新日期:2011-04-12 00:00:00

  • Effects of combined or separate 5,7-dihydroxytryptamine lesions of the dorsal and median raphe nuclei on responding maintained by a DRL 20s schedule of food reinforcement.

    abstract::Previous studies have shown that long-term 5-hydroxytryptamine (5-HT) depletion induced by combined dorsal and median raphe injections of 5,7-dihydroxytryptamine (5,7-DHT) leads to impairments in the acquisition and performance of behaviour maintained under a differential-reinforcement-of-low-rate (DRL) schedule of re...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(95)00037-q

    authors: Fletcher PJ

    更新日期:1995-03-27 00:00:00

  • Reversal of organophosphate-induced muscle block by neomycin.

    abstract::The organophosphate, diisopropyl fluorophosphate, and the aminoglycoside antibiotic, neomycin, both independently block neuromuscular transmission. At the neuromuscular junction, neomycin reduces the presynaptic release of acetylcholine, whereas diisopropyl fluorophosphate irreversibly inhibits acetylcholinesterase, t...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(86)90098-3

    authors: Bradley RJ

    更新日期:1986-09-03 00:00:00

  • Vasoactive intestinal polypeptide increases inositol phospholipid breakdown in the rat superior cervical ganglion.

    abstract::The effects of VIP and of peptides of the VIP family: secretin, glucagon, the porcine histidine isoleucine containing peptide (PHI) and the rat hypothalamic growth hormone-releasing hormone (rhGRF) on the cyclic AMP and inositol phosphate contents of isolated rat superior cervical ganglia were investigated. We demonst...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(86)90200-3

    authors: Audigier S,Barberis C,Jard S

    更新日期:1986-06-25 00:00:00

  • Identification of MSH release-inhibiting elements in the neurointermediate lobe of the rat.

    abstract::Neurointermediate lobes of rats comprise elements which, when excited in vitro, bring about an inhibition of the release of melanocyte stimulating hormone (MSH). Superfusion of neurointermediate lobes of intact donor rats with medium containing 45 mM K+ induced a stimulation of the release of oxytocin, arginine-vasopr...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(79)91047-3

    authors: Tilders FJ,van der Woude HA,Swaab DF,Mulder AH

    更新日期:1979-08-10 00:00:00

  • Evidence of a physiological role for neuropeptide Y in ventromedial hypothalamic lesion-induced hyperphagia.

    abstract::We evaluated the role of neuropeptide Y (NPY), a potent endogenous orexigenic signal, in the ventromedial hypothalamic (VMH) lesion-induced hyperphagia in rats. To produce hyperphagia and excessive weight gain, adult female rats received bilateral electrolytic or sham lesions in the VMH. Concurrently, a permanent intr...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(95)00644-6

    authors: Dube MG,Kalra PS,Crowley WR,Kalra SP

    更新日期:1995-09-04 00:00:00

  • Electroshock afterdischarges are related to neuronal oscillability: neuronal models of Aplysia.

    abstract::Identifiable giant neurons of Aplysia explored intracellularly behave differently at the offset of an intracellular electroshock (IES) or after a synaptic 'tetanization', according to their functional type: neurons of the stable type depolarize and fire at the offset of the IES, anodal or cathodal, thus eliciting an a...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(82)90583-2

    authors: Chalazonitis N,Boisson M,Rome-Talbot D,Chagneux R

    更新日期:1982-09-30 00:00:00