The proportion of neurons in the rat neostriatum that project to the substantia nigra demonstrated using horseradish peroxidase conjugated with wheatgerm agglutinin.

abstract：:The two inbred strains of mice C57BL/6 and DBA/2 are characterized by a different behavioral reactivity to cholinergic agents during development. The present experiment revealed that the strain-dependent differences in cholinergic-mediated analgesia during development disappeared during adult life. In fact, oxotremori...

journal_title：Brain research

authors： Fagioli S,Consorti D,Pavone F

更新日期：1990-02-26 00:00:00

abstract：:Using a dual-serial-arithmetic paradigm, we examined whether a capacity limitation constrains the neural activation that underlies dual-task performance. Six conditions were run in the experiment (the baseline, single-addition, single-subtraction, dual-addition, dual-subtraction, and the dual-operation condition). In ...

journal_title：Brain research

authors： Kuo BC,Yeh YY,Chen DY,Liang KC,Chen JH

更新日期：2008-03-14 00:00:00

abstract：:A method to study the protein binding patterns of trace elements in human cerebrospinal fluid (CSF) is described. Proteins in CSF samples were separated by size exclusion chromatography combined with high performance liquid chromatography (SEC-HPLC). The column was calibrated to separate proteins in the molecular weig...

journal_title：Brain research

authors： Gellein K,Roos PM,Evje L,Vesterberg O,Flaten TP,Nordberg M,Syversen T

更新日期：2007-10-12 00:00:00

abstract：:This study examines the preventive and therapeutic effects of curcumin on brain edema after hypoxic-ischemic brain damage (HIBD) in a rat model. Male Sprague-Dawley rats were divided into four groups: a sham group (SH), a hypoxic-ischemic group (HI) without drug treatment, a hypoxic-ischemic group (CU) with curcumin i...

journal_title：Brain research

authors： Yu L,Yi J,Ye G,Zheng Y,Song Z,Yang Y,Song Y,Wang Z,Bao Q

更新日期：2012-09-26 00:00:00

abstract：:Subcommissural organ (SCO) is a highly specialized ependymal gland located in the roof of the third ventricle. The secretory products of the SCO, which condense to form Reissner's fiber (RF), were recently found to cross-react with the anti-calcitonin antibody. To understand the mechanisms regulating the formation of ...

journal_title：Brain research

authors： Saha SG,Jain MR,Subhedar N

更新日期：2000-01-10 00:00:00

abstract：:The aim of this investigation was to determine the incidence of seizure activity in the acute phase following traumatic brain injury. Compression contusion trauma was produced in the right parietal cortex in 19 artificially ventilated rats. Electroencephalographic recordings were carried out in 17 of the animals for 2...

journal_title：Brain research

authors： Nilsson P,Ronne-Engström E,Flink R,Ungerstedt U,Carlson H,Hillered L

更新日期：1994-02-21 00:00:00

abstract：BACKGROUND:Perinatal brain injury in preterm infants is a major cause of neurological handicap. The role of the neurotrophin receptor p75 (p75(NTR)) in the pathogenesis and repair of neonatal excitotoxic brain injury is unknown. Depending on a complex interplay of neurotrophin signalling, p75(NTR) can, in addition to i...

journal_title：Brain research

authors： Griesmaier E,Schlager G,Wegleiter K,Hermann M,Urbanek M,Simbruner G,Keller M

更新日期：2010-10-08 00:00:00

abstract：:The chemokines CCL2 and CCL7 are upregulated in the brain during several neurodegenerative and acute diseases associated with infiltration of peripheral leukocytes. Astrocytes can respond to inflammatory cytokines like IL-1beta and TNF-alpha by producing chemokines. This study aims to test the ability of IL-1beta and ...

journal_title：Brain research

authors： Thompson WL,Van Eldik LJ

更新日期：2009-09-01 00:00:00

abstract：:The central axon of a primary afferent neuron that responded to light mechanical stimulation of the lower premolar teeth in a fast adapting fashion was intra-axonally injected with horseradish peroxidase in the cat. The labeled terminals within the rostrodorsomedial (Vo.r) and dorsomedial (Vo.dm) parts of subnucleus o...

journal_title：Brain research

authors： Bae YC,Nagase Y,Yoshida A,Shigenaga Y,Sugimoto T

更新日期：1993-03-19 00:00:00

abstract：:The activity of 294 single units was recorded from the dorsolateral prefrontal cortex of monkeys performing two visual discrimination tasks with delayed response. One task, delayed matching-to-sample (DMS), required memory of a colored cue for later (18 s) matching and choice of color; the cue did not connote the loca...

journal_title：Brain research

authors： Quintana J,Yajeya J,Fuster JM

更新日期：1988-12-06 00:00:00

abstract：:To date several circuities in supraspinal site of the central nervous system have been known to engage in pain modulation. Lateral hypothalamus (LH) is known as part of the circuit of pain modulation among supraspinal sites. Its role in several animal pain models has been well defined. In this study, we examined the r...

journal_title：Brain research

authors： Salehi S,Kashfi K,Manaheji H,Haghparast A

更新日期：2020-04-01 00:00:00

abstract：:NO performs a wide array of cell signaling functions. Neuronal NO synthase (nNOS) immunoreactivity and nicotinamide adenine dinucleotide phosphate diaphorase (NDP) activity, a marker of nNOS, were concentrated at adult rat neuromuscular junctions and persisted in denervated muscle indicating the localization of the en...

journal_title：Brain research

authors： Kusner LL,Kaminski HJ

更新日期：1996-08-19 00:00:00

abstract：:Novel neurorehabilitative strategies are needed to improve motor outcomes following stroke. Based on the disynaptic excitatory projections of the dentatothalamocortical pathway to the motor cortex as well as to anterior and posterior cortical areas, we hypothesize that chronic electrical stimulation of the contralesio...

journal_title：Brain research

authors： Machado AG,Baker KB,Schuster D,Butler RS,Rezai A

更新日期：2009-07-14 00:00:00

abstract：:Rat striata were exposed to 15 mM quinolinic acid (QUIN), or QUIN plus the nitric oxide synthase inhibitors S-methyl-L-thiocitrulline dihydrochloride (L-MIN) or 7-nitroindazole monosodium salt (7-NINA) for 21 days. Co-administration of 100 microM or 1 mM L-MIN with QUIN significantly reduced lesion volume compared to ...

journal_title：Brain research

authors： Bazzett T,Geiger A,Coppola B,Albin R

更新日期：1997-11-14 00:00:00

abstract：:Brain iron overload has a detrimental role in brain injury after intracerebral hemorrhage (ICH). Lipocalin 2 (LCN2), a siderophore-binding protein, is involved in cellular iron transport. The present study investigated changes in LCN2 expression after ICH and the role of iron in those changes. Male Sprague-Dawley rats...

journal_title：Brain research

authors： Dong M,Xi G,Keep RF,Hua Y

更新日期：2013-04-10 00:00:00

abstract：:The activity of choline kinase (CK) was examined in the rat superior cervical ganglion (SCG) during development and following postganglionic axotomy. The highest specific enzyme activity (nmol phosphorylcholine/mg protein/h) 52 +/- 8, is observed 5 d before birth, then it rapidly decreases by about 50%, reaching at th...

journal_title：Brain research

authors： Gilad GM,Gilad VH

更新日期：1981-09-14 00:00:00

abstract：:Acetylcholinesterase (AchE) is an important peripheral membrane-bound enzyme, crucial for cholinergic neurotransmission. Changes in AchE activity, kinetic and thermotropic properties were studied in hepatic encephalopathy (HE) associated with acute liver failure induced experimentally by the administration of the hepa...

journal_title：Brain research

authors： Swapna I,SathyaSaikumar KV,Murthy ChR,Gupta AD,Senthilkumaran B

更新日期：2007-06-11 00:00:00

abstract：:In recent years microvillar cells (MVC) have been identified in the olfactory epithelium of numerous species, including rodents, canines, and primates. However, there is no consensus on the morphologic or histochemical features of this cell, nor is the function of these cells currently known. Previous studies have exa...

journal_title：Brain research

authors： Miller ML,Andringa A,Evans JE,Hastings L

更新日期：1995-01-09 00:00:00

abstract：:This study shows that permanent cell lines can be established from rat and mouse brain by direct tissue culture methodology without the aid of exogenous chemical or viral transforming agents. These cells were derived from specific areas of the brain, such as the cerebellum and hippocampus, at chosen times during fetal...

journal_title：Brain research

authors： Bulloch K,Stallcup WB,Cohn M

更新日期：1977-10-21 00:00:00

abstract：:Although Rolling mouse Nagoya (RMN) has been considered to demonstrate cerebellar dysfunction, our previous metabolic and electrophysiological studies also revealed a dysfunction of the basal ganglia, with the presumable primary site of dysfunction being the striatum. In the present study, we investigated the neuroche...

journal_title：Brain research

authors： Taniwaki T,Shinoda H,Kaseda Y,Kato M,Goto I

更新日期：1996-04-01 00:00:00

abstract：:Excitatory and inhibitory synapses may control neuronal output through a push-pull mechanism--that is, increases in excitation are coupled to simultaneous decreases in inhibition or vice versa. This pattern of activity is characteristic of excitatory and inhibitory vestibulospinal axons that mediate vestibulocollic re...

journal_title：Brain research

authors： Grande G,Bui TV,Rose PK

更新日期：2010-05-28 00:00:00

abstract：:The morphological characteristics, distribution and neurochemical phenotype of striatal neuronal subtypes expressing the GABA(A) receptor alpha3-subunit were investigated using immunocytochemical and immunofluorescent techniques with an antibody specific for this subunit. alpha3-immunopositive neurons were infrequent ...

journal_title：Brain research

authors： Rodríguez-Pallares J,Labandeira-García JL,Muñoz A,Caruncho HJ

更新日期：2000-09-08 00:00:00

abstract：:Dendrites were transected 100 microns from nerve cell somata. The probability of cell survival increased as a function of the extent of proximal segment retraction. The retraction effect is probably the result of increased resistance to calcium and sodium currents at the lesion. It is speculated that limitation of ner...

journal_title：Brain research

authors： Lucas JH

更新日期：1987-11-10 00:00:00

abstract：:The administration of alpha 2-adrenoreceptor antagonists SKF 64139 or SKF 72223 (TIQ derivatives) elicits an increase in striatal DOPA synthesis. The findings that the enhanced DOPA synthesis is reversed by pretreatment of the animals with clonidine or with the D beta H inhibitor FLA-63 suggest that action of the TIQ ...

journal_title：Brain research

authors： Rabey JM,Passeltiner P,Bystritsky A,Engel J,Goldstein M

更新日期：1981-12-28 00:00:00

abstract：:The aim of this investigation was to determine whether an ingredient of green tea, epigallocatechin gallate (EGCG) could attenuate oxidative stress-induced degeneration of the retina as occurs in age-related macular degeneration (AMD) and glaucoma. Initial in vitro studies on brain membranes showed that EGCG was appro...

journal_title：Brain research

authors： Zhang B,Osborne NN

更新日期：2006-12-08 00:00:00

abstract：:'Spontaneous' and visually evoked action potentials were recorded from single neurons in cytoarchitectonic area 17 (striate cortex, area V1) of anaesthetized and immobilized cats, prior to, during and after brief reversible inactivation of the ipsilateral postero-temporal visual (PTV) cortex (presumed homologue of pri...

journal_title：Brain research

authors： Huang JY,Wang C,Dreher B

更新日期：2007-03-23 00:00:00

abstract：:Choroid plexuses from the lateral (LVCP) and fourth ventricles (FVCP) of rats or rabbits were incubated in artificial cerebrospinal fluid (CSF) containing 1 microM [14C]L-carnitine with various concentrations of L-carnitine ranging from 0.01 mM to 1.0 mM. The time course of 1 microM [14C]L-carnitine uptake by the chor...

journal_title：Brain research

authors： Kim CS,Roe CR

更新日期：1991-07-19 00:00:00

abstract：:Experiments were conducted to (1) provide further evidence of the selectivity of [D-Ala2,Leu5,Cys6]enkephalin (DALCE) as an antagonist of delta (delta) receptor ligands and (2) use DALCE as a tool to explore the possible role of delta receptors in restraint stress. Dose- and time-response curves were generated for the...

journal_title：Brain research

authors： Calcagnetti DJ,Bowen WD,Holtzman SG

更新日期：1990-02-19 00:00:00

abstract：:Beta-amyloid peptide (Aβ) has a causal role in the pathophysiology of Alzheimer's disease (AD). Recent studies indicate that Aβ can disrupt excitatory glutamatergic synaptic function at synaptic level. However, the underlying mechanisms remain obscure. In this study, we recorded evoked and spontaneous EPSCs in hippoca...

journal_title：Brain research

authors： Yao W,Zou HJ,Sun D,Ren SQ

更新日期：2013-06-17 00:00:00

abstract：:This review summarizes the anatomical and functional organization of the frontal cortex of the rat in comparison to primates. Lesions of the primary motor or of the prefrontal cortex of both primates and rodents produce a consistent constellation of symptoms that are strikingly similar across species as diverse as rat...

journal_title：Brain research

authors： Kolb B

更新日期：1984-11-01 00:00:00