Effects of curcumin on levels of nitric oxide synthase and AQP-4 in a rat model of hypoxia-ischemic brain damage.

abstract：:By means of an immunohistochemical technique, we examined the neuronal induction of 72-kDa heat shock protein (HSP72) in response to methamphetamine-induced hyperthermia in the mouse hippocampus. Strong HSP72 immunoreactivity (ir) was found in the neurons of hippocampus proper, particularly in the CA1/2 and medical CA...

journal_title：Brain research

authors： Goto S,Korematsu K,Oyama T,Yamada K,Hamada J,Inoue N,Nagahiro S,Ushio Y

更新日期：1993-10-29 00:00:00

abstract：:The patterns of preganglionic projections in the avian sympathetic system are highly specific. Preganglionic axons arising from the T1 spinal segment, for example, project predominantly in the rostral direction, whereas T4 preganglionic axons project predominantly in the caudal direction. Moreover, each ganglion recei...

journal_title：Brain research

authors： Yip JW

更新日期：1987-03-01 00:00:00

abstract：:Serotonin 1A (5HT1A) receptor agonists have shown neuroprotective properties in different models of central nervous system injury. Activation of neuronal 5HT1A receptors appears to be involved in the neuroprotective effects. It remains to be elucidated if astroglial cells are responsive to the 5HT1A neuroprotective ef...

journal_title：Brain research

authors： Ramos AJ,Rubio MD,Defagot C,Hischberg L,Villar MJ,Brusco A

更新日期：2004-12-31 00:00:00

abstract：:To understand the functional organization of the piriform cortex (PC), the axon collaterals of three pyramidal cells in layer IIb of the anterior PC and one pyramidal cell in layer IIb of the posterior PC were labeled and quantitatively analyzed by intracellular biocytin injection in the guinea pig. Single pyramidal c...

journal_title：Brain research

authors： ul Quraish A,Yang J,Murakami K,Oda S,Takayanagi M,Kimura A,Kakuta S,Kishi K

更新日期：2004-11-05 00:00:00

abstract：:Cerebellar explants derived from neonatal mice were exposed to cytosine arabinoside, an inhibitor of DNA synthesis. Following such exposure, the cortical regions of the explants contained numerous closely packed large neurons with few intervening elements and without lamination. The surviving large cortical neurons in...

journal_title：Brain research

authors： Seil FJ,Leiman AL,Woodward WR

更新日期：1980-03-31 00:00:00

abstract：:A neuron׳s response to a sound can be suppressed by the presentation of a preceding sound. It has been suggested that this suppression is a direct correlate of the psychophysical phenomenon of forward masking, however, forward suppression, as measured in the responses of the auditory nerve, was insufficient to account...

journal_title：Brain research

authors： Ingham NJ,Itatani N,Bleeck S,Winter IM

更新日期：2016-05-15 00:00:00

abstract：:The expression of phosphorylated extracellular signal-regulated kinase 1/2 (pERK 1/2) was evaluated in the vestibular nuclei (VN) of rats following unilateral labyrinthectomy (UL). Immunohistochemistry revealed a significant asymmetrical increase in pERK 1/2 expression in the VN, 5 min after UL, after which pERK 1/2 i...

journal_title：Brain research

authors： Kim MS,Choi MA,Choi DO,Lee MY,Kim KY,Rhee JK,Jin YZ,Park BR

更新日期：2004-06-18 00:00:00

abstract：:In degenerating frog sciatic nerves an in situ perfusion technique was used to measure the permeability coefficient-surface area product (PA) of endoneurial capillaries to [14C]sucrose, and the endoneurial vascular space (V). Both PA and V started to increase after the 3rd day of degeneration. The increase in PA peake...

journal_title：Brain research

authors： Weerasuriya A

更新日期：1988-03-29 00:00:00

abstract：:Pituitary adenylate cyclase activating polypeptide (PACAP) is a hypothalamic peptide that affects anterior pituitary cell function. This study examined the effects of PACAP on prolactin (PRL) release in vivo and on tyrosine hydroxylase (TH) activity in tuberoinfundibular dopaminergic neurons in vivo and in vitro. In o...

journal_title：Brain research

authors： Arbogast LA,Voogt JL

更新日期：1994-08-29 00:00:00

abstract：:The action of gamma-aminobutyric acid (GABA) in the supraoptic nucleus was investigated using guinea pig brain slices. GABA produced a membrane depolarization accompanied by a decrease in the input resistance. The action of GABA was concentration-dependent throughout a wide range of concentrations (10(-7)-10(-3) M). I...

journal_title：Brain research

authors： Ogata N

更新日期：1987-02-17 00:00:00

abstract：:Benzodiazepine (BZ) site ligands affect vigilance, anxiety, memory processes, muscle tone and epileptogenic propensity through modulation of neurotransmission at GABA(A) receptors containing alpha1, alpha2, alpha3 or alpha5 subunits, and may have numerous experimental and clinical applications. The ability of non-sele...

journal_title：Brain research

authors： Savić MM,Clayton T,Furtmüller R,Gavrilović I,Samardzić J,Savić S,Huck S,Sieghart W,Cook JM

更新日期：2008-05-07 00:00:00

abstract：:The optic nerve of anesthetized cats was completely cut and the autologous sciatic nerve was transplanted. Sixty days later some populations of retinal ganglion cells were shown to regenerate the axon with retrograde HRP labeling. We verified that ganglion cells that had projected to the lateral geniculate nucleus (LG...

journal_title：Brain research

authors： Watanabe M,Sawai H,Fukuda Y

更新日期：1991-09-27 00:00:00

abstract：:Trophic effects of neurturin, a member of the glial cell line-derived neurotrophic factor-family, have been demonstrated on mesencephalic dopaminergic neurons, suggesting its therapeutic potential for Parkinson's disease. This study was designed to test the neuroprotective and regenerative effects of an intrastriatal ...

journal_title：Brain research

authors： Oiwa Y,Yoshimura R,Nakai K,Itakura T

更新日期：2002-08-30 00:00:00

abstract：:The distribution of retinal ganglion cells (RGCs) providing input to the thalamofugal visual system in the pigeon was studied with an anatomical transneuronal transport technique using the fluorescent dye rhodamine beta-isothiocyanate (RITC). Unilateral injections of RITC made into the telencephalic visual Wulst resul...

journal_title：Brain research

authors： Miceli D,Repérant J,Medina M,Volle M,Rio JP

更新日期：2006-07-07 00:00:00

abstract：:In this study, we have identified and characterized 5-HT3-like receptors in the rat medial prefrontal cortex (mPFc), an area with a moderate density of 5-HT3 binding sites, using the techniques of single unit recording and microiontophoresis. The microiontophoresis of the 5-HT3 receptor agonist 2-methylserotonin (2-Me...

journal_title：Brain research

authors： Ashby CR Jr,Minabe Y,Edwards E,Wang RY

更新日期：1991-06-07 00:00:00

abstract：:Nuclear retention of radioactivity was studied in neural estrogen target cells 15 min-7 h after i.v. injection of [3H]estradiol. Maximal uptake occurred by 15 min. Cells of the medial preoptic nucleus retained the label longer than did those of the medial amygdaloid nucleus. Cells of the ventromedial nucleus and arcua...

journal_title：Brain research

authors： Keefer DA

更新日期：1981-12-14 00:00:00

abstract：:Results from clinical studies provide evidence that cognitive changes relatively late in life may be traced to antecedent conditions including diabetes, obesity, a sedentary lifestyle, and an atherogenic diet. As such, several traits of Type 2 diabetes (T2DM) could be considered pathogenic factors of aging, contributi...

journal_title：Brain research

authors： Maimaiti S,DeMoll C,Anderson KL,Griggs RB,Taylor BK,Porter NM,Thibault O

更新日期：2015-09-24 00:00:00

abstract：:Mechanical hyperalgesia is an early symptom of diabetic neuropathy. To evaluate the mechanisms underlying this symptom, it was studied and compared in rat models of systemic and local hyperglycemia. Systemic hyperglycemia was induced by a single injection of streptozotocin (STZ, 50 mg/kg). Local hyperglycemia either i...

journal_title：Brain research

authors： Dobretsov M,Hastings SL,Romanovsky D,Stimers JR,Zhang JM

更新日期：2003-01-17 00:00:00

abstract：:A polyclonal antiserum raised against the carboxy-terminal 17 amino acids of the rat p185c-neu (anct) reacted with a 140 kDa polypeptide in membranes of synaptosome fractions from neocortex and hippocampus of 11-day-old and adult rats. The same antiserum reacted with a 185 kDa polypeptide in microsome membranes from r...

journal_title：Brain research

authors： Stieber A,Chen Y,Gonatas J,Dougall W,Qian X,O'Rourke D,Samanta A,Greene MI,Gonatas NK

更新日期：1995-11-27 00:00:00

abstract：:Fast cyclic voltammetry (FCV) at carbon fibre microelectrodes was used to monitor stimulated noradrenaline (NA) efflux in slices of the ventral part of the rat bed nucleus of stria terminalis (BSTV) superfused with artificial cerebrospinal fluid at 32 degrees C. NA efflux was evoked by local electrical stimulation (tr...

journal_title：Brain research

authors： Palij P,Stamford JA

更新日期：1993-04-02 00:00:00

abstract：:The ontogeny of gonadotropin-releasing hormone (GnRH) systems was investigated in 3 anuran amphibians (genus Rana) by means of immunocytochemical (ICC) techniques and antibodies generated against 3 different forms of GnRH. Antisera that recognize primarily chicken II and mammalian GnRHs revealed two anatomically and d...

journal_title：Brain research

authors： Muske LE,Moore FL

更新日期：1990-11-26 00:00:00

abstract：:Male laboratory rats were raised in two colonies, each of 27 rats, and then given intraventricular injections of the norepinephrine neurotoxin 6-hydroxydopamine (6-OHDA) or the serotonin neurotoxin 5,6-dihydroxytryptamine (5,6-DHT) or saline. They were then returned to their enclosure and behavior during the next 50 d...

journal_title：Brain research

authors： Ellison G

更新日期：1976-02-13 00:00:00

abstract：:Transplantation of fetal substantia nigra into the brain can alleviate some of the manifestations of animal models of Parkinson's disease. The purpose of the present experiment was to determine the optimal embryonic donor age for solid tissue substantia nigra grafts. Rats with unilateral substantia nigra lesions were ...

journal_title：Brain research

authors： Simonds GR,Freed WJ

更新日期：1990-10-15 00:00:00

abstract：:The contribution of the pedunculopontine nucleus to exploratory locomotion was investigated in rats. Locomotor activity recorded in a standard open-field apparatus was increased more than two-fold when wooden panels were inserted. This novelty-elicited locomotion was reduced significantly when procaine was injected bi...

journal_title：Brain research

authors： Mogenson GJ,Wu M,Tsai CT

更新日期：1989-04-24 00:00:00

abstract：:We investigated the effects of neonatal optic nerve transection on cortical acetylcholinesterase (AChE) activity in hooded rats during postnatal development and following behavioral manipulation after weaning. AChE reaction product was quantified on digitized images of histochemically stained sections in layer IV of p...

journal_title：Brain research

authors： Melzer P,Mineo L,Ebner FF

更新日期：2007-03-30 00:00:00

abstract：:Amino acid uptake by slices of brain is greatly diminished by incubation of the slices in glucose-free media. Uptake can be restored by the addition of a number of substrates, e.g., lactate, citrate, or oxaloacetate. The mixture of succinate, malate, and pyruvate (SMP, 20, 5, and mM) restored amino acid uptake better ...

journal_title：Brain research

authors： Teller DN,Bana-Schwartz M,Deguzman T,Lajtha A

更新日期：1977-08-12 00:00:00

abstract：:Sardinian alcohol non-preferring (sNP) rats, selected for their low ethanol preference and consumption, carry a point mutation (R100Q) in the gene coding for GABA(A) receptor alpha(6) subunit, which becomes more sensitive to diazepam-evoked GABA currents. We performed binding studies in the cerebellum of normal (RR) a...

journal_title：Brain research

authors： Sanna A,Congeddu E,Porcella A,Saba L,Pistis M,Peis M,Marchese G,Ruiu S,Lobina C,Grayson DR,Gessa GL,Pani L

更新日期：2003-03-28 00:00:00

abstract：:Wayfinding is a complex cognitive function involving different types of information, such as knowledge about landmarks and direction information. This variety of processes suggest that multiple neural mechanisms are involved, e.g., the hippocampal system, the posterior parietal and temporal cortical areas. Although pa...

journal_title：Brain research

authors： van Asselen M,Kessels RP,Kappelle LJ,Neggers SF,Frijns CJ,Postma A

更新日期：2006-01-05 00:00:00

abstract：:[125I]CGP 42112, first developed to identify angiotensin II receptor subtype 2 (AT2), was recently shown to bind to a novel non-angiotensin binding site in injured rat brain tissue. We addressed the question whether non-angiotensin [125I]CGP 42112 binding appears after kainic acid induced hippocampal neurodegeneration...

journal_title：Brain research

authors： Jöhren O,Viswanathan M,Saavedra JM

更新日期：1995-12-08 00:00:00

abstract：:It has been previously observed that taurine inhibits PKC-activated phosphorylation of specific proteins including a approximately 20k Mr protein in rat cortical synaptosomes. In the present study, the mechanism of the above effects of taurine were investigated. In an intrasynaptosomal cytosol fraction obtained by sub...

journal_title：Brain research

authors： Li YP,Lombardini JB

更新日期：1991-07-05 00:00:00