Asymmetric activation of extracellular signal-regulated kinase 1/2 in rat vestibular nuclei by unilateral labyrinthectomy.

abstract：:Effects of taurine on endogenous aspartic acid (Asp), glutamic acid (Glu) and gamma-aminobutyric acid (GABA) release has been investigated using synaptosomes prepared from rat cerebral cortex. Although basal release of these amino acids was not affected, taurine inhibited KCl (30 mM)-evoked overflow of Asp, Glu and GA...

journal_title：Brain research

authors： Kamisaki Y,Maeda K,Ishimura M,Omura H,Itoh T

更新日期：1993-11-12 00:00:00

abstract：:Heme oxygenase-carbon monoxide-cGMP (HO-CO-cGMP) pathway has been reported to be involved in peripheral and spinal modulation of inflammatory pain. However, the involvement of this pathway in the modulation of acute painful stimulus in the absence of inflammation remains unknown. Thus, we evaluated the involvement of ...

journal_title：Brain research

authors： Carvalho PG,Branco LG,Panissi CR

更新日期：2011-04-18 00:00:00

abstract：:Neuroglobin (Ngb) and Cytoglobin (Cygb) are new members of the globin family and display heterotopic expression patterns. To examine the effect of different hypoxia profiles on expression of Ngb and Cygb in rodent brain, rats were exposed to either sustained hypoxia (SH; 10% O(2)) or intermittent hypoxia (IH; 10% and ...

journal_title：Brain research

authors： Li RC,Lee SK,Pouranfar F,Brittian KR,Clair HB,Row BW,Wang Y,Gozal D

更新日期：2006-06-22 00:00:00

abstract：:Stimuli such as noise or hypoxia can induce a release of ATP into the cochlear fluid spaces. At nanomolar concentrations, ATP affects neurotransmission and electrochemical regulation of sound transduction. At higher concentrations, ATP may exert cytotoxicity acting on specific P2X(7) receptor subunits, thus contributi...

journal_title：Brain research

authors： Vlajkovic SM,Vinayagamoorthy A,Thorne PR,Robson SC,Wang CJ,Housley GD

更新日期：2006-08-09 00:00:00

abstract：:Numerous studies with PC12 cells have suggested that the mitogen-activated protein (MAP) kinase pathway might play a major role in the neuronal differentiation that is induced by nerve growth factor (NGF). Cells of the PC12D subline extend neurites within several hours in response to NGF in the presence of inhibitors ...

journal_title：Brain research

authors： Sano M,Kitajima S

更新日期：1998-03-02 00:00:00

abstract：:The afferent connections of the eye of Python reticulatus have been studied with HRP, Nuclear yellow and Granular blue. It appeared that in this snake the eye receives afferent connections from basal telencephalic areas both ipsi- and contralaterally. Following experiments in which Granular blue was injected into one ...

journal_title：Brain research

authors： Hoogland PV,Welker E

更新日期：1981-05-25 00:00:00

abstract：:An HRP study of the frog's superior olivary nucleus (SON) revealed that it (1) receives reciprocal tonotopic projections from dorsal medullary nuclei and principal nuclei of the torus semicircularis (TS) bilaterally; (2) receives bilateral projections from caudalis nuclei and brainstem reticular nuclei, and unilateral...

journal_title：Brain research

authors： Feng AS

更新日期：1986-01-29 00:00:00

abstract：:A large body of evidence shows that methamphetamine (METH) causes sustained damage to the brain in animal models and human METH users. In chronic users there are indications of cognitive and motor deficits. Striatal neuropeptides are in a position to modulate the neurochemical effects of METH and consequently striatal...

journal_title：Brain research

authors： Afanador L,Mexhitaj I,Diaz C,Ordonez D,Baker L,Angulo JA

更新日期：2013-05-13 00:00:00

abstract：:Chronic total sleep deprivation (TSD) of rats by the disk-over-water method reliably produces initial increases and subsequent decreases in waking intraperitoneal (Tip) and hypothalamic (Thy) temperatures, progressive increases in energy expenditure, skin lesions on the tail and plantar surfaces, debilitated appearanc...

journal_title：Brain research

authors： Feng PF,Bergmann BM,Rechtschaffen A

更新日期：1995-12-12 00:00:00

abstract：:Three experiments were conducted to test the hypothesis that brain corticotropin-releasing hormone (CRH) systems mediate stress-induced freezing behavior, an index of a rat's level of fear. We administered i.c.v. 0-50 micrograms of alpha-helical CRH9-41 (a specific CRH antagonist) before foot shock and showed that thi...

journal_title：Brain research

authors： Kalin NH,Sherman JE,Takahashi LK

更新日期：1988-08-02 00:00:00

abstract：:Maternal infection during pregnancy is associated with an increased risk of neurodevelopmental injury. Our aim was to investigate whether prenatal immune challenge could alter susceptibility to seizure-induced brain injury in adulthood. Pregnant Wistar rats were injected intraperitoneally with lipopolysaccharide (LPS)...

journal_title：Brain research

authors： Yin P,Liu J,Li Z,Wang YY,Qiao NN,Huang SY,Li BM,Sun RP

更新日期：2013-06-26 00:00:00

abstract：:Sites which bind oxytocin and vasopressin with high affinity were detected in the brain and upper spinal cord of 12 human subjects, using in vitro light microscopic autoradiography. Tissue sections were incubated with tritiated vasopressin, tritiated oxytocin or an iodinated oxytocin antagonist. The ligand specificity...

journal_title：Brain research

authors： Loup F,Tribollet E,Dubois-Dauphin M,Dreifuss JJ

更新日期：1991-08-02 00:00:00

abstract：:The density of binding sites for excitatory amino acids in the hippocampus of SDAT (senile dementia of the Alzheimer type) patients has been investigated. This was compared to that found in younger and old non-dement cases. In the SDAT hippocampi there was a significant decrease in the glutamate and kainate binding. T...

journal_title：Brain research

authors： Represa A,Duyckaerts C,Tremblay E,Hauw JJ,Ben-Ari Y

更新日期：1988-08-09 00:00:00

abstract：:Reduced glutathione (GSH) plays an important role in cellular protection against damage from free radicals and other electrophiles. GSH in the rat central nervous system was quantitatively analyzed. In adult brain, tissue from the cerebellum and cerebrum had higher GSH levels than that from the brainstem and spinal co...

journal_title：Brain research

authors： Kudo H,Kokunai T,Kondoh T,Tamaki N,Matsumoto S

更新日期：1990-03-19 00:00:00

abstract：:The locus coeruleus was stimulated in 62 cats in order to investigate the effect on cephalic blood flow and cephalic vascular resistance. Flow was measured by electromagnetic flow probes applied to the common carotid artery. Stimulation over a range of frequencies (0.2-200 s-1) produced a frequency-dependent fall in c...

journal_title：Brain research

authors： Goadsby PJ,Lambert GA,Lance JW

更新日期：1983-11-14 00:00:00

abstract：:The role of calcium and protein kinases in rhythmic activity induced by muscarinic receptor activation in the CA1 area in rat hippocampal slices was investigated. Extracellular recording showed that carbachol (20 microM) induced synchronized field potential activity with a dominant frequency of 7.39+/-0.68 Hz. Pretrea...

journal_title：Brain research

authors： Alberi S,Boeijinga PH,Raggenbass M,Boddeke HW

更新日期：2000-07-28 00:00:00

abstract：:Prairie voles (Microtus ochrogaster) are monogamous rodents that display high levels of affiliative behaviors, including pair-bonding, biparental care, and cooperative breeding. Species differences in basal cocaine- and amphetamine-regulated transcript (CART) mRNA and peptide expression have been found between prairie...

journal_title：Brain research

authors： Hostetler CM,Kowalczyk AS,Griffin LL,Bales KL

更新日期：2011-09-26 00:00:00

abstract：:Intra- and interhemispheric connections between the anterior ectosylvian visual area (AEV) and other visual cortical areas including the lateral suprasylvian (LSS) were examined in the cat using the retrograde double-label fluorescence technique. The areal and laminar distributions of labeled neurons were mapped follo...

journal_title：Brain research

authors： Miceli D,Repérant J,Ptito M

更新日期：1985-11-18 00:00:00

abstract：:Inflammation and immunity play a crucial role in the pathogenesis of cerebral vasospasm after subarachnoid hemorrhage (SAH). Recently, a growing body of evidence indicates that Toll-like receptor (TLR) 4 is vital for inflammation and immunity. Therefore, this study aimed to detect the expression of TLR4 in the basilar...

journal_title：Brain research

authors： Zhou ML,Wu W,Ding YS,Zhang FF,Hang CH,Wang HD,Cheng HL,Yin HX,Shi JX

更新日期：2007-10-10 00:00:00

abstract：:An analysis of cellular kinetics during closure of the cranial neural folds in the C57BL mouse at 8 and 9 days gestations was obtained by means of tritiated thymidine autoradiography. At 8 days the short generation time (7.5 h) and high labeling index (61.4%) are evidence of intensive proliferative activity occurring ...

journal_title：Brain research

authors： Wilson DB

更新日期：1981-10-01 00:00:00

abstract：:The onset of adult hypothyroidism causes neuronal damage in the CA3 hippocampal region, which is attenuated by T(4) administration. We analyzed the expression of molecular proliferation markers (Cyclin D1 and PCNA), cellular damage-arrest (p53 and p21), and apoptosis (Bax/Bcl-2 index) in the hippocampus of hypothyroid...

journal_title：Brain research

authors： Alva-Sánchez C,Sánchez-Huerta K,Arroyo-Helguera O,Anguiano B,Aceves C,Pacheco-Rosado J

更新日期：2009-05-19 00:00:00

abstract：:The purpose of the present study is to characterize the striatum of the lamprey by immunohistochemical and tracing techniques. Cells immunoreactive for GABA and substance P (SP), and positive for acetylcholinesterase, are present in the lamprey striatum. Immunoreactive (ir) fibers were detected by antisera raised agai...

journal_title：Brain research

authors： Pombal MA,El Manira A,Grillner S

更新日期：1997-08-22 00:00:00

abstract：:The acute intravenous administration of high doses of methylprednisolone sodium succinate (15-90 mg/kg) to cats enhanced (Na+ + K+)-ATPase activity as much as 2-fold in synaptosomes prepared from lumbar spinal cord removed following drug administration. The effect was apparent within 5 min and was statistically signif...

journal_title：Brain research

authors： Braughler JM,Hall ED

更新日期：1981-08-31 00:00:00

abstract：:The postnatal development of cat triceps surae gamma-motoneurones, retrogradely labelled with horseradish peroxidase (HRP), was studied light and electron microscopically. The mean diameter of the cell bodies of the gamma-motoneurones increased by about 25% from birth to the adult stage, which was much less than the i...

journal_title：Brain research

authors： Arvidsson U,Svedlund J,Lagerbäck PA,Cullheim S

更新日期：1987-12-15 00:00:00

abstract：:Previous studies have shown that long-term 5-hydroxytryptamine (5-HT) depletion induced by combined dorsal and median raphe injections of 5,7-dihydroxytryptamine (5,7-DHT) leads to impairments in the acquisition and performance of behaviour maintained under a differential-reinforcement-of-low-rate (DRL) schedule of re...

journal_title：Brain research

authors： Fletcher PJ

更新日期：1995-03-27 00:00:00

abstract：:[1-14C]Octanoate (OCTO) is rapidly extracted from blood and metabolized by brain. Up to 6 min following an intravenous pulse injection the autoradiographic pattern of brain labeling reflects differences in blood flow and energy metabolism. When animals are given OCTO during visual or somatosensory stimulation the auto...

journal_title：Brain research

authors： Rowley H,Collins RC

更新日期：1985-06-03 00:00:00

abstract：:The effect of monocular enucleation on basophilic and metabolic staining in primary (striate) visual cortex has been compared in Old and New World monkeys. Both species show a 30-40% shrinkage of neurons in the layers of dorsal lateral geniculate nucleus receiving axons from the enucleated eye. In striate cortex Old W...

journal_title：Brain research

authors： Hendrickson AE,Tigges M

更新日期：1985-05-06 00:00:00

abstract：OBJECTIVE:To investigate the effect of salvinorin A (SA) on brain injury and neurologic function post-brain ischemia/reperfusion (I/R) using a rat forebrain ischemia model and further explore the effect of kappa opioid receptor (KOR) inhibition by SA on aquaporin-4 (AQP4) expression in the hippocampus, cortex and stria...

journal_title：Brain research

authors： Xin J,Zhang Y,He Z,Wang Z

更新日期：2016-04-15 00:00:00

abstract：:Experiments were conducted to examine sex differences in striatal dopamine function using in vivo microdialysis in freely moving rats. We report here a sex difference in basal extracellular striatal dopamine determined by quantitative microdialysis (the no net flux method) when castrated and ovariectomized rats were c...

journal_title：Brain research

authors： Castner SA,Xiao L,Becker JB

更新日期：1993-04-30 00:00:00

abstract：:Swelling of glial and nerve cells is characteristic of brain damage in cerebral ischemia or trauma. The therapeutical efficiency of inhibition of Cl(-)-transport by a novel antagonist, the diuretic torasemide, on cytotoxic swelling of glial cells from lactacidosis, or glutamate was analyzed. Lactacidosis and the inter...

journal_title：Brain research

authors： Staub F,Peters J,Kempski O,Schneider GH,Schürer L,Baethmann A

更新日期：1993-04-30 00:00:00