Abstract:
:Reduced glutathione (GSH) plays an important role in cellular protection against damage from free radicals and other electrophiles. GSH in the rat central nervous system was quantitatively analyzed. In adult brain, tissue from the cerebellum and cerebrum had higher GSH levels than that from the brainstem and spinal cord. Infant cerebrum and cerebellum contained lower levels of GSH than adult cerebrum and cerebellum. These data seem to suggest that the brainstem and spinal cord in adults, and the cerebrum and cerebellum in infants, are more vulnerable to injury by free radical-like radiation than the cerebrum and cerebellum in adults.
journal_name
Brain Resjournal_title
Brain researchauthors
Kudo H,Kokunai T,Kondoh T,Tamaki N,Matsumoto Sdoi
10.1016/0006-8993(90)90178-esubject
Has Abstractpub_date
1990-03-19 00:00:00pages
326-8issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(90)90178-Ejournal_volume
511pub_type
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