Abstract：
:Membrane properties of rat magnocellular neuroendocrine cells (MNCs) were examined during intracellular recordings in vivo. Current-clamp experiments revealed sustained outward rectification positive to -55 mV and transient outward rectification of depolarizing responses elicited from negative holding potentials. Trains of impulses were associated with a progressive increase of spike duration. Such features, which were not observed in neighboring non-neuroendocrine cells, are similar to those of MNCs in slices or explants of rat hypothalamus. In contrast, however, cells recorded in vivo were characterized by intense synaptic inhibition and a lower specific impedance than commonly observed from MNCs impaled in vitro.
journal_name
Brain Resjournal_title
Brain researchauthors
Bourque CW,Renaud LPdoi
10.1016/0006-8993(91)90535-4subject
Has Abstractpub_date
1991-02-01 00:00:00pages
349-52issue
1-2eissn
0006-8993issn
1872-6240pii
0006-8993(91)90535-4journal_volume
540pub_type
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