Abstract：
:Hypothalamus and frontal cortex beta-adrenergic receptors, as measured by [125I]cyanopindolol binding, were investigated in male rats both after 4 days of acute starvation and after 2 weeks of semistarvation with dietary manipulation. Moreover, to test whether lymphocyte beta 2-adrenergic receptors can be used as a marker for brain beta-receptors, the parallel measurement of beta-adrenoceptors of lymphocyte, hypothalamus and frontal cortex was carried out in acutely starved rats. T3 and corticosterone in rat serum were also determined in this study. Our experiments showed that beta-adrenergic receptors in hypothalamus and frontal cortex, as well as those in lymphocytes remain unaltered in rats starved acutely for 4 days when compared with controls, despite reduced T3 and increased corticosterone levels. Chronic semistarvation on either a protein-rich or a carbohydrate-rich diet also resulted in decreased T3, increased corticosterone and no alterations of beta-adrenergic receptors in hypothalamus and frontal cortex.
journal_name
Brain Resjournal_title
Brain researchauthors
Lonati-Galligani Mdoi
10.1016/0006-8993(88)91519-3subject
Has Abstractpub_date
1988-03-01 00:00:00pages
329-34issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(88)91519-3journal_volume
442pub_type
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