Abstract：
:The purpose of the present study is to characterize the striatum of the lamprey by immunohistochemical and tracing techniques. Cells immunoreactive for GABA and substance P (SP), and positive for acetylcholinesterase, are present in the lamprey striatum. Immunoreactive (ir) fibers were detected by antisera raised against SP, dopamine, enkephalin and serotonin. These immunoreactive fibers were mainly located in the periventricular neuropil that borders the striatum and in which GABAergic striatal neurons distributed their dendritic arbors. Putative connections between the striatum, the ventral part of the lateral pallium, and the diencephalic motor centers involved in the control of locomotion were studied by using fluorescein-coupled dextran amines (FDA) as a tracer. The striatum projects to the ventral part of the lateral pallium (lpv), where GABA-ir cells and SP-ir fibers were also present. The lpv in turn projects to the ventral thalamus, which has descending connections to the reticulospinal cells involved in the control of locomotion. These results, together with previous findings of histaminergic and neurotensin projections, suggest that the lamprey striatum and its inputs with regard to neurotransmitters/modulators are very similar to those of modem amniotes, including primates, and are thus conserved to a high degree.
journal_name
Brain Resjournal_title
Brain researchauthors
Pombal MA,El Manira A,Grillner Sdoi
10.1016/s0006-8993(97)00701-4subject
Has Abstractpub_date
1997-08-22 00:00:00pages
249-54issue
1-2eissn
0006-8993issn
1872-6240pii
S0006-8993(97)00701-4journal_volume
766pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract：:Morphological and physiological effects of kainic acid (KA) lesions in rat ventral lateral geniculate nucleus (LGV) were studied 1.5 and 6 h after KA injection. Morphological changes were examined mainly by electron micrographs. At 1.5 h after KA injection dendrites were dilated and some vacuolations occurred in both ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(89)90033-4
更新日期：1989-03-27 00:00:00
abstract：:Most experimental spinal cord injury studies described to date have relied on a limited number of injury gradations, and have tacitly assumed that outcome (functional, histological, and/or neurophysiological) is a monotonically graded function of injury severity. In contrast, the present study provides evidence that f...
journal_title：Brain research
pub_type： 杂志文章
doi：
更新日期：1996-08-05 00:00:00
abstract：:We have investigated the influence of central noradrenergic and dopaminergic systems on the susceptibility of rats to seizures in the kainic acid (KA)-model of epilepsy. In the dose range of 0.75 to 10 mg/kg s.c., KA dose-dependently induced characteristic behavioural changes. Partial depletion of noradrenaline (NA) a...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(89)90219-9
更新日期：1989-08-28 00:00:00
abstract：:Large bilateral aspiration lesions of the hippocampus had no significant effect on septal kindling, whereas large bilateral DC lesions of the pyriform lobe resulted in a small but significant increase in the number of septal stimulations required to complete kindling. Bilateral aspiration lesions of the dorsal hippoca...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(88)90826-8
更新日期：1988-06-28 00:00:00
abstract：:The effect of the non-phenothiazine calmodulin-inhibitor R 24571 on transmitter release at the frog neuromuscular junction has been investigated. MEPP frequency was reduced by 25-40% at low concentrations of the drug (2-5 X 10(-7) M) but increased at higher concentrations. These effects were independent of [Ca2+]o. EP...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)90379-8
更新日期：1985-11-25 00:00:00
abstract：:Rats anticipate a scheduled daily meal by entrainment of a circadian pacemaker separate from the light-entrainable circadian pacemaker located in the suprachiasmatic nuclei (SCN). The site and molecular mechanisms of the food-entrainable pacemaker are unknown. The intrinsic period (tau) of the SCN pacemaker is signifi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(01)03042-6
更新日期：2001-11-23 00:00:00
abstract：:The hypothalamic angiotensin II (Ang II) system plays an important role in pituitary hormone release. Little is known about this system in the mouse brain. We studied the distribution of angiotensin-converting-enzyme (ACE), Ang II, Ang II receptor subtypes, and vasopressin in the hypothalamus of adult male mice. Autor...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(97)00220-5
更新日期：1997-05-23 00:00:00
abstract：:The synaptic regulatory mechanism of resting membrane potential of layer III and V pyramidal neurons was analyzed intracellularly in the slice preparation of cat sensorimotor cortex. During the tetanic stimulation of white matter, subthreshold membrane depolarization was induced, and after that, a slowly developing hy...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(00)02353-2
更新日期：2000-06-30 00:00:00
abstract：:The development from primary to augmenting responses of somatosensory (SI) cortical area to low-frequency stimulation of the ventrobasal (VB) thalamus or white matter (WM) beneath SI in VB-lesioned preparations was studied by field potential analysis and extracellular unit recording. Compared to the major postsynaptic...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(81)90719-8
更新日期：1981-01-26 00:00:00
abstract：:Epidemiological studies indicate that women have a higher risk of Alzheimer's disease (AD) even after adjustment for age. Though transgenic mouse models of AD develop AD-related amyloid beta (Abeta) and/or tau pathology, gender differences have not been well documented in these models. In this study, we found that fem...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2008.03.079
更新日期：2008-06-24 00:00:00
abstract：:Theory of Mind (ToM) has been defined as our ability to predict behaviors of others in terms of their underlying intentions. While the developmental trajectory of ToM had been thought to be invariant across cultures, several ToM studies conducted outside the Anglo-American cultural or linguistic milieus have obtained ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2007.06.022
更新日期：2007-08-20 00:00:00
abstract：:Repeating a stimulus generally leads to a decreased response in neural activity compared to that for novel items. This neural attenuation provides a marker for stimulus-specific perceptual encoding and memory that can be detected using functional magnetic resonance imaging (fMRI). Although previously assumed to occur ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2006.01.090
更新日期：2006-03-29 00:00:00
abstract：:We studied the effects of nitric oxide (NO) and the NO-releasing agents sodium nitroprusside (SNP), S-nitroso-N-acetylpenicillamine (SNAP) and isosorbide dinitrate (ISDN) on N-methyl-D-aspartate (NMDA)-induced increases in intracellular Ca2+ ([Ca2+]i), whole-cell patch-clamp currents and on glutamate-stimulated [3H]di...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(92)91690-g
更新日期：1992-10-02 00:00:00
abstract：:The activity of incertohypothalamic, tuberoinfundibular, mesolimbic and nigrostriatal dopamine (DA) neurons was estimated by measuring the rate of turnover of DA (decline of DA after alpha-methyltyrosine) in brain regions containing the cell bodies and terminals of these neurons. Estradiol benzoate (25 micrograms/kg/d...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(84)90267-1
更新日期：1984-12-03 00:00:00
abstract：:Blink movement metrics were studied in three alert cynomolgus monkeys using electromagnetic search coils attached to the eyelids bilaterally. Monkey blinks averaged approximately 24 degrees. Down-phase peak velocities were approximately twice those of the corresponding up phases. Most blinks were symmetrical with clos...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)90869-o
更新日期：1993-04-23 00:00:00
abstract：:Correlative light and electron microscopic methods were used to examine the morphology, distribution and synaptic connections of double bouquet cells immunoreactive for the calcium-binding protein calbindin D-28k in the human temporal neocortex. Double bouquet cells form symmetric synapses with small dendritic shafts ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(95)00641-3
更新日期：1995-08-28 00:00:00
abstract：:The effect of bombesin on the activity of dopamine (DA) neurons comprising the nigrostriatal, mesolimbic, tuberoinfundibular and tuberohypophysial systems in the male rat was determined by measuring: (1) the accumulation of 3,4-dihydroxyphenylalanine (DOPA) after administration of a decarboxylase inhibitor, and (2) th...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(91)91745-m
更新日期：1991-11-22 00:00:00
abstract：:Sustained neuroinflammation contributes to the pathogenesis of postoperative cognitive dysfunction. Dexmedetomidine, a selective α-2 adrenergic receptor agonist, exhibits a protective role in the brain. This study investigated whether dexmedetomidine pretreatment attenuates neuroinflammation induced by tibial fracture...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2016.04.074
更新日期：2016-08-01 00:00:00
abstract：:Adult male rats, intact (N) or with complete (CHD), anterior (AHD), or posterior (PHD) hypothalamic deafferentations were bilaterally adrenalectomized. At 3, 6, 12 and 20 days post-adrenalectomy they were decapitated and trunk blood was collected for ACTH determinations. In N rats, ACTH markedly elevated up to 850 pg/...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(84)90127-6
更新日期：1984-11-26 00:00:00
abstract：:Individual variability in the behavioral responsiveness to psychostimulant drugs is due, in part, to genetic factors. The present study investigated the effects of acute and repeated administrations of cocaine (0, 5, 10 or 20 mg/kg, i.p.) on locomotor activity in male and female rats from genetically distinct strains ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(99)01742-4
更新日期：1999-09-18 00:00:00
abstract：:To investigate the reversibility of neuronal functions during deep and mild hypothermia, we have examined changes in membrane properties of pyramidal neurons of the CA3 region of hippocampal slices during cooling and rewarming (8 approximately 37 degrees C) of the perfusion medium. Hypothermia reduced the excitatory p...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(00)03285-6
更新日期：2001-03-02 00:00:00
abstract：:Soluble guanylyl cyclase is a heterodimeric (alpha, beta) enzyme generating the second messenger, cGMP, upon activation by the gaseous messenger, nitric oxide. The occurrence and distribution of alpha 1-, alpha 2-, beta 1- and beta 2-subunits were investigated in trigeminal and dorsal root ganglia on the mRNA and the ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(96)00097-2
更新日期：1996-05-20 00:00:00
abstract：:Excitotoxic neuronal death underlies many neurodegenerative disorders. Because cannabinoid receptor agonists act presynaptically to inhibit glutamate release, we examined the effects of Win 55212-2, a full agonist at CB(1) receptors, and Delta(9)-tetrahydrocannabinol (THC), a partial agonist, on the survival of neuron...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2006.03.011
更新日期：2007-01-12 00:00:00
abstract：:The effects on fusimotor discharge rate of algesic agents (bradykinin, potassium chloride, histamine, 5-hydroxytryptamine) and lactic acid, applied by close arterial injection into triceps surae muscles, were investigated in decerebrate cats. Fusimotor discharge was recorded from filaments dissected free from otherwis...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)91528-o
更新日期：1990-06-25 00:00:00
abstract：:In six decerebrated and in eight alpha-chloralose anesthetized, paralyzed and mechanically ventilated beagle dogs, we have studied involvement of glutamate and glutamate receptors in transmission of excitatory inputs from the airway sensory receptors to the nucleus tractus solitarius and from this site to airway-relat...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(00)02890-0
更新日期：2000-11-10 00:00:00
abstract：:This study used microdialysis to monitor extracellular levels of 5-HT and its metabolite, 5-hydroxyindole acetic acid (5-HIAA) in the lateral hypothalamus (LH) and hippocampus of freely moving rats that had developed a CTA to a 2.5 mM saccharin solution (CS) following its pairing with illness induced by lithium chlori...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(91)90551-6
更新日期：1991-08-09 00:00:00
abstract：:The present study compared Fos expression in identified hypothalamic magnocellular neurons in lactating and non-lactating female rats submitted to acute haemorrhage or 24 h of water deprivation, stimuli that induce the release of both oxytocin and vasopressin. Quantitative analysis of preparations doubly immunostained...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(94)90809-5
更新日期：1994-10-31 00:00:00
abstract：:Variables influencing decision-making in real settings, as in the case of voting decisions, are uncontrollable and in many times even unknown to the experimenter. In this case, the experimenter has to study the intention to decide (vote) as close as possible in time to the moment of the real decision (election day). H...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2010.06.046
更新日期：2010-09-10 00:00:00
abstract：:Sex hormone binding globulin (SHBG) is found in the brain and acts directly on plasma membrane-associated receptors in the prostate gland. Infusing SHBG into the medial preoptic area or medial basal hypothalamus of female rats increases their female sexual receptivity. SHBG, SHBG plus estradiol (SHBG-E), and SHBG-E pl...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(00)02569-5
更新日期：2000-08-18 00:00:00
abstract：:We have used magnetic resonance imaging (MRI) of the living rat brain to longitudinally analyze the ontogenesis of an ibotenic acid lesion targeted at the piriform cortex. The MRI data were systematically compared with data obtained from a battery of histopathological techniques, including Nissl stain, hematoxylin sta...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(96)00058-3
更新日期：1996-04-29 00:00:00
