The regulation of striatal DOPA synthesis by alpha 2-adrenoreceptors.

abstract：:The distribution of degeneration in the vestibular nuclei (VN) has been studied in transversely cut sections from 9 cats with stereotaxically performed lesions in the main reticular formation (RF) of the brain stem (Nauta of Fink and Heimer method). No projection was found from the mesencephalic reticular formation (R...

journal_title：Brain research

authors： Hoddevik GH,Brodal A,Walberg F

更新日期：1975-09-05 00:00:00

abstract：:Chicks of 1-8 days after hatching were submitted to unilateral visual deprivation and, in both optic lobes, muscarinic receptors, labeled with L-[3H]quinuclidinyl benzylate [( 3H]L-QNB) and acetylcholinesterase (AChE) were assayed. Between 1 and 6 days the number of [3H]L-QNB binding sites was lower in the contralater...

journal_title：Brain research

authors： Jerusalinsky DA,De Robertis E

更新日期：1984-06-01 00:00:00

abstract：:Positron emission tomography, using the dopa analogue [18F]6-fluoro-L-dopa, has been used to depict the neostriatum in living monkeys. The amount of 18F that accumulated preferentially in the striatum could be augmented by a peripheral decarboxylase inhibitor. Striatal 18F could also be discharged with reserpine. This...

journal_title：Brain research

authors： Garnett S,Firnau G,Nahmias C,Chirakal R

更新日期：1983-11-28 00:00:00

abstract：:The present study examined whether the inhibition of serotonin transporters (SERT) contributes to cocaine- and other local anesthetics-induced convulsions, and which subtypes of 5-HT receptor are involved in the convulsions. For this purpose, cocaine, meprylcaine and lidocaine, all of which have different effects on S...

journal_title：Brain research

authors： Morita K,Hamamoto M,Arai S,Kitayama S,Irifune M,Kawahara M,Kihira K,Dohi T

更新日期：2005-09-28 00:00:00

abstract：:The 'wobbler' mutant mouse can be recognized at about 4 weeks of age by its tremor and atrophy of forelimb muscles. In addition to degeneration of spinal motoneurons, especially in cervical spinal cord, selected bulbar motoneurons have also been reported to degenerate in the mutant. We examined a cranial motor nucleus...

journal_title：Brain research

authors： LaVail JH,Koo EH,Dekker NP

更新日期：1987-02-24 00:00:00

abstract：:Serotonin 1A receptor (5-HT(1A)R) agonists have emerged as valuable supplements to l-DOPA therapy, demonstrating that they can decrease side effects and enhance motor function in animal models of Parkinson's disease (PD) and human PD patients. The precise mechanism by which these receptors act remains unknown and ther...

journal_title：Brain research

authors： Dupre KB,Eskow KL,Negron G,Bishop C

更新日期：2007-07-16 00:00:00

abstract：:The dtsz mutant hamster represents a model of primary paroxysmal dystonia, in which dystonic episodes occur in response to stress. Previous examinations demonstrated striatal dysfunctions in dtsz hamsters. In the present study, in situ hybridization was used to examine preproenkephalin and prodynorphin expression as p...

journal_title：Brain research

authors： Nobrega JN,Parkes JH,Wong P,Raymond R,Richter A

更新日期：2004-07-23 00:00:00

abstract：:These studies examined whether posttraining activation of alpha1-noradrenergic receptors in the nucleus tractus solitarius (NTS) influences neural processes that are involved in encoding information into memory. Different groups of male Sprague-Dawley rats were trained in two separate learning tasks. In experiment 1, ...

journal_title：Brain research

authors： Miyashita T,Williams CL

更新日期：2003-10-17 00:00:00

abstract：:Vasopressinergic structures were examined within the magnocellular nuclei of the human basal forebrain. Vasopressinergic neurons were found in all parts of the diagonal band nucleus, and less frequently in the anteromedial subnucleus of the basal nucleus (Meynert). They belong to the group of large multipolar neurons,...

journal_title：Brain research

authors： Ulfig N,Braak E,Ohm TG,Pool CW

更新日期：1990-10-15 00:00:00

abstract：:We have previously used organotypic cultures to study mechanisms regulating phenotypic expression of neurotransmitter characters in the brain. Our previous work indicated that nerve growth factor (NGF) specifically increased the activity of choline acetyltransferase (CAT) in striatal cholinergic interneurons. In the p...

journal_title：Brain research

authors： Martínez HJ,Dreyfus CF,Jonakait GM,Black IB

更新日期：1987-06-02 00:00:00

abstract：:Defeat stress in mice, a model of social stress, increases benzodiazepine receptor binding as measured by specific [3H]Ro15-1788 binding in vivo, but not by [3H]flunitrazepam binding in vitro. This increase occurs rapidly, by 20 min following exposure to stress, and resolves by 60 min. Increased benzodiazepine recepto...

journal_title：Brain research

authors： Miller LG,Thompson ML,Greenblatt DJ,Deutsch SI,Shader RI,Paul SM

更新日期：1987-06-30 00:00:00

abstract：:Recent immunohistochemical studies have suggested that the forebrain distribution of stigmoid bodies, marked by an antibody against placental aromatase-associated antigen X-P2 (PAX), overlaps with that of the common binding sites of androgen and estrogen. In the present light- and electron-microscopy study the coexist...

journal_title：Brain research

authors： Nagano M,Shinoda K

更新日期：1994-01-21 00:00:00

abstract：:Overactivation of poly (ADP-ribose) polymerase-1 (PARP-1) in response to DNA damage is considered to play a crucial role in the development of post-ischemic neuronal injury, such as ischemic stroke. The present study was undertaken to clarify the beneficial effects of MP-124, a novel PARP-1 inhibitor, on neurological ...

journal_title：Brain research

authors： Matsuura S,Egi Y,Yuki S,Horikawa T,Satoh H,Akira T

更新日期：2011-09-02 00:00:00

abstract：:Fetal exposure to dexamethasone (DEX) alters brain plasticity and cognitive functions during adulthood in a sex-dependent manner. The mechanisms underlying such long-lasting sex-dependent change of prenatal DEX is not well understood. The p73 gene plays an important role in brain development. It encodes for two protei...

journal_title：Brain research

authors： Abul M,Al-Bader MD,Mouihate A

更新日期：2019-03-15 00:00:00

abstract：:Within the framework of the dual process model of recognition memory, prior work with event-related potentials (ERPs) has suggested that an early component, the FN400, is a correlate of familiarity while a later component, the Late Positive Complex (LPC), is a correlate of recollection. However, other work has questio...

journal_title：Brain research

authors： Wolk DA,Schacter DL,Lygizos M,Sen NM,Holcomb PJ,Daffner KR,Budson AE

更新日期：2006-06-22 00:00:00

abstract：:Event-related potentials (ERPs) were recorded using a large electrode array while subjects engaged in tasks designed to dissociate control from storage/maintenance processes in verbal working memory (WM). Increased ERP negativity (450-900 ms post-stimulus onset) over left frontal regions emerged only when required dyn...

journal_title：Brain research

authors： Kiss I,Watter S,Heisz JJ,Shedden JM

更新日期：2007-10-03 00:00:00

abstract：:While exercise is commonly recommended for PD patients to improve motor function, little is known about the disease-altering potential of exercise. Although others have demonstrated neuroprotective or neurorestorative effects of exercise in animal models of PD, the majority of these studies utilize young animals. In o...

journal_title：Brain research

authors： Hood RL,Liguore WA,Moore C,Pflibsen L,Meshul CK

更新日期：2016-09-01 00:00:00

abstract：:Large neurons in the neostriatum of patients with Alzheimer's disease (AD) and progressive supranuclear palsy (PSP) were investigated topographically, histologically and ultrastructurally. The number of large neurons whose nuclear area is greater than 101 microns2 was uniformly decreased in the neostriatum in PSP, but...

journal_title：Brain research

authors： Oyanagi K,Takahashi H,Wakabayashi K,Ikuta F

更新日期：1991-03-29 00:00:00

abstract：:Response conflict can be induced by priming multiple responses competing for control of action in trials. The N2 is one functionally-related cognitive control index for response conflict. And yet the underlying whiter matter neural substrates of inter-individual difference in conflict N2 remain unclear. So the aim of ...

journal_title：Brain research

authors： Gao S,Liu P,Guo J,Zhu Y,Liu P,Sun J,Yang X,Qin W

更新日期：2017-12-01 00:00:00

abstract：:GEC1 protein shares high identity with GABARAP (GABA(A) Receptor-Associated Protein), interacts with tubulin and GABA(A) receptors and is potentially involved in intracellular transport processes. Recently, using quantitative real time PCR, we have reported the gec1 mRNA expression in different rat brain areas. In the...

journal_title：Brain research

authors： Tolle F,Risold PY,Mansuy-Schlick V,Rossi E,Boyer-Guittaut M,Fraichard A,Jouvenot M

更新日期：2008-05-19 00:00:00

abstract：:The hypothalamic paraventricular nucleus is known to send projections to the dorsal medullary area where it appears to innervate the nucleus tractus solitarius and the dorsal motor nucleus of the vagus. Experiments were carried out in urethane anesthetized rats to identify single vagal motor neurons identified by anti...

journal_title：Brain research

authors： Lawrence D,Pittman QJ

更新日期：1985-04-15 00:00:00

abstract：:We have previously shown that blockade of neurotransmission mediated by gamma-aminobutyric acid (GABA) in the ventromedial nucleus of the hypothalamus (VMH) by the microinjection of a GABAA receptor antagonist, bicuculline methiodide (BM), exclusively induced running activity in the rat. The purpose of the present stu...

journal_title：Brain research

authors： Narita K,Yokawa T,Nishihara M,Takahashi M

更新日期：1993-02-19 00:00:00

abstract：:An immunohistochemical investigation of the bovine pineal gland was performed using both a rabbit polyclonal antibody and a rat monoclonal antibody against choline acetyltransferase (ChAT). A network of ChAT-immunoreactive (IR) nerve fibers was located throughout the pineal gland, both in the perivascular spaces and b...

journal_title：Brain research

authors： Phansuwan-Pujito P,Mikkelsen JD,Govitrapong P,Møller M

更新日期：1991-04-05 00:00:00

abstract：:In the context of injury to the corticospinal tract (CST), brainstem-origin circuits may provide an alternative system of descending motor influence. However, subcortical circuits are largely under subconscious control. To improve volitional control over spared fibers after CST injury, we hypothesized that a combinati...

journal_title：Brain research

authors： Harel NY,Yigitkanli K,Fu Y,Cafferty WB,Strittmatter SM

更新日期：2013-11-13 00:00:00

abstract：:The present study evaluated the central effects of beta-funaltrexamine (B-FNA), a non-equilibrium antagonist of mu-opioid receptors and a reversible agonist of kappa-opioid receptors upon food intake in rats under freely-feeding, deprivation and glucoprivic conditions. B-FNA elicited distinct short-term and long-term ...

journal_title：Brain research

authors： Arjune D,Standifer KM,Pasternak GW,Bodnar RJ

更新日期：1990-12-03 00:00:00

abstract：:Nerve growth factor (NGF) transported intraaxonally from the adrenergic nerve terminals in the iris to the cell bodies in the superior cervical ganglion resulted in an increase in the activity of the enzyme ornithine decarboxylase in the ganglion. This occurred in both six-day-old and adult rats with the relative effe...

journal_title：Brain research

authors： Hendry IA,Bonyhady R

更新日期：1980-10-27 00:00:00

abstract：:A monospecific antibody against tyrosine hydroxylase (TH), purified from a transplantable rat pheochromocytoma, was produced in rabbits. Immunohistochemical techniques were employed in order to determine if a relationship exists between the subcellular distribution of TH and the level of activation of the enzyme in th...

journal_title：Brain research

authors： Stephens JK,Masserano JM,Vulliet PR,Weiner N,Nakane PK

更新日期：1981-03-30 00:00:00

abstract：:GABAA receptors (GABAARs) and glycine receptors (GlyRs) are two principal inhibitory chloride ion channels in the central nervous system. The two receptors do not function independently but cross-talk to each other, i.e., the activation of one receptor would inhibit the other. This cross-talk is present in different p...

journal_title：Brain research

authors： Tang ZQ,Lu YG,Huang YN,Chen L

更新日期：2020-12-01 00:00:00

abstract：:A qualitative immunohistochemical study was performed on calcineurin A- and calbindin-positive neurons in the spinal cord of transgenic mice, an animal model of amyotrophic lateral sclerosis, carrying the G93A mutation of the Cu/Zn-superoxide dismutase gene. The results show that calcineurin A-immunoreactive motoneuro...

journal_title：Brain research

authors： Knirsch U,Sturm S,Reuter A,Bachus R,Gosztonyi G,Voelkel H,Ludolph AC

更新日期：2001-01-19 00:00:00

abstract：:The effects of infusing N-methyl-d-aspartate (NMDA) into the raphe nuclei on release of 5-HT in this brain region and also the frontal cortex of the same animal were studied using in vivo microdialysis in freely moving rats. Infusion of 25 microM NMDA into the raphe led to a substantial decrease in dialysate 5-HT in t...

journal_title：Brain research

authors： Pallotta M,Segieth J,Whitton PS

更新日期：1998-02-09 00:00:00