Abstract:
:The 'wobbler' mutant mouse can be recognized at about 4 weeks of age by its tremor and atrophy of forelimb muscles. In addition to degeneration of spinal motoneurons, especially in cervical spinal cord, selected bulbar motoneurons have also been reported to degenerate in the mutant. We examined a cranial motor nucleus and found a 31% loss of abducens motoneurons in 4-5-week-old wobbler mice as compared to age-matched control mice.
journal_name
Brain Resjournal_title
Brain researchauthors
LaVail JH,Koo EH,Dekker NPdoi
10.1016/0006-8993(87)91363-1subject
Has Abstractpub_date
1987-02-24 00:00:00pages
127-32issue
1-2eissn
0006-8993issn
1872-6240pii
0006-8993(87)91363-1journal_volume
404pub_type
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