Decarboxylation of L-dopa by cultured mouse astrocytes.

abstract：:Fifty-three cell pairs in the somatosensory cerebral cortex were examined in pentobarbital-anesthetized cats for evidence of short latency interactions. Many neuronal pairs separated by distances of 150 to 500 micron were observed to have temporal dependencies. In a subset of 19 pairs where the surrounding multiunit a...

journal_title：Brain research

authors： Metherate R,Dykes RW

更新日期：1985-08-19 00:00:00

abstract：:The cortex receives a cholinergic input which is considered to be involved in mediating the effects of arousal. The experiments reported here have examined the nature of the cholinergic influence on the neuronal organization of the cat visual cortex. Out of 83 cells studied, 92% exhibited a modification in their visua...

journal_title：Brain research

authors： Sillito AM,Kemp JA

更新日期：1983-12-19 00:00:00

abstract：:Unanesthetized adult male rats with indwelling right atrial cannulae were used in the majority of experiments. Morphine (MOR, 3.0 mg/kg) caused a large but transient increase in both GH and PRL levels, which could be prevented with naloxone. Disruption of central noradrenergic function with diethyldithiocarbamate (400...

journal_title：Brain research

authors： Koenig J,Mayfield MA,Coppings RJ,McCann SM,Krulich L

更新日期：1980-09-22 00:00:00

abstract：:In adult rodents, neuroblasts originating from the subventricular zone migrate tangentially through the rostral migratory stream (RMS) toward the olfactory bulb where they differentiate into interneurons. Neuroblasts in the RMS migrate in chains for a long distance along specifically arranged blood vessels which promo...

journal_title：Brain research

authors： Angelidis A,Račeková E,Arnoul P,Závodská M,Raček A,Martončíková M

更新日期：2018-11-01 00:00:00

abstract：:One-day-old chicks were exposed for 60 min to either an imprinting stimulus or a dark-box. They were killed at 0, 1, 6 or 12 h after the end of this treatment, and the activities of acetylcholinesterase (AChE) and choline acetyltransferase (ChAc) assayed in the forebrain roof, forebrain base and midbrain. The activity...

journal_title：Brain research

authors： Haywood J,Hambley J,Rose S

更新日期：1975-07-11 00:00:00

abstract：:The effect of intracerebroventricular (i.c.v.) infusion of various iso- and hypertonic saccharide solutions on water intake stimulated by intracarotid (i.c.) infusion of hypertonic NaCl was studied in sheep. Without an i.c.v. infusion, water intake during a 10-min period following an i.c. infusion of 4 M NaCl (1.4 ml/...

journal_title：Brain research

authors： Park R,Denton DA,McKinley MJ,Pennington G,Weisinger RS

更新日期：1989-07-24 00:00:00

abstract：:Using a mouse model of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced Parkinson's disease (PD), this study investigated on the neuroprotective effects of acupuncture by examining whether acupuncture contributed to inhibiting microglial activation and inflammatory events. C57BL/6 mice were treated with MPT...

journal_title：Brain research

authors： Kang JM,Park HJ,Choi YG,Choe IH,Park JH,Kim YS,Lim S

更新日期：2007-02-02 00:00:00

abstract：:Adrenergic innervation of tibial and vagus nerves was studied after 1-16 weeks duration of streptozotocin (STZ)-induced diabetes in rats. Sucrose-phosphate glyoxylic acid (SPG) histochemistry and the formaldehyde-induced fluorescence (FIF) method were used to demonstrate adrenergic nerve fibers in the epi-perineurial ...

journal_title：Brain research

authors： Koistinaho J,Wadhwani KC,Rapoport SI

更新日期：1990-04-09 00:00:00

abstract：:Effects of pre-treatment of synaptic membranes with beta-adrenoceptor agonists and cholera toxin on [3H]clonidine and [3H]yohimbine binding were examined in rat cerebral cortex. Pre-incubation of cerebral cortical membranes with isoproterenol (10 or 200 microM) or dobutamine (1, 10 or 200 microM) at 37 degrees C for 4...

journal_title：Brain research

authors： Kitamura Y,Nomura Y

更新日期：1985-03-11 00:00:00

abstract：:The present study investigated whether the effects of central cholinergic stimulation on thermoregulation during exercise are modulated by arterial baroreceptors. Wistar rats were submitted to sinoaortic denervation (SAD) or sham denervation (SHAM) and then fitted with a chronic guide cannula into the lateral cerebral...

journal_title：Brain research

authors： Pires W,Wanner SP,Lima MR,Oliveira BM,Guimarães JB,de Lima DC,Haibara AS,Rodrigues LO,Coimbra CC,Lima NR

更新日期：2010-12-17 00:00:00

abstract：:When female golden hamsters are maintained on a photoperiod of less than 12.5 h of light per day, they go into a pineal gland-induced anestrus in 6-10 weeks. This acyclicity is similar in certain respects to the testicular regression which occurs in male golden hamsters maintained on a short photoperiod. A recent stud...

journal_title：Brain research

authors： Pieper DR,Samyn MM,Heverly RN

更新日期：1986-08-13 00:00:00

abstract：:Nitric oxide (NO) production in the sensory neurons of the rad nodose ganglion was studied by examining the distribuiotn of NO synthase (NOS) by use of NADPH diaphorase (NADPHD) histochemistry and immunohistochemistry ofr the presence of isoformes of NOS: neuronal (nNOS), endothelial (eNOS) and the inducible isoform (...

journal_title：Brain research

authors： Yamamoto Y,Henrich M,Snipes RL,Kummer W

更新日期：2003-01-24 00:00:00

abstract：:Ramified microglial cells were investigated in primary cultures of dissociated cerebral cortical tissue from rats. The identification of these cells was confirmed through immunohistochemical staining with 7 monoclonal antibodies selective for microglia. While there was significant variation in staining intensity with ...

journal_title：Brain research

authors： Booth PL,Thomas WE

更新日期：1991-05-10 00:00:00

abstract：:Dopamine-beta-hydroxylase (DBH), the enzyme that converts dopamine to norepinephrine, has been localized in light and electron microscopic preparations of rat brain by an immunocytochemical method using a peroxidase--anti-peroxidase Fab complex. In light microscopic preparations, DBH-specific reaction product was obse...

journal_title：Brain research

authors： Cimarusti DL,Saito K,Vaughn JE,Barber R,Roberts E,Thomas PE

更新日期：1979-02-16 00:00:00

abstract：:Prior studies indicate that, in tests of recognition memory, ERPs elicited by correctly recognized test items differ according to whether the items were encoded in an emotionally arousing or an emotionally neutral study context. These prior studies employed only a relatively brief (ca. 10 min) retention interval, howe...

journal_title：Brain research

authors： Jaeger A,Johnson JD,Corona M,Rugg MD

更新日期：2009-05-07 00:00:00

abstract：:Glutamate kills sensitive neurons through several steps downstream to receptor activation: increased free Ca2+ levels, activation of various enzymes and accumulation of reactive oxygen species (ROS). We have evaluated in a well established model of neuronal cultures the neuroprotective effects of blocking these mechan...

journal_title：Brain research

authors： Ciani E,Grøneng L,Voltattorni M,Rolseth V,Contestabile A,Paulsen RE

更新日期：1996-07-22 00:00:00

abstract：:Intracellular recordings of the spontaneous activity were obtained from neurons in long-term cultures from the area of the supraoptic nucleus of rats. The effects of various substances known from in situ studies to cause vasopressin release were analyzed. Application of nicotine or acetylcholine induced a transition f...

journal_title：Brain research

authors： Gähwiler BH,Dreifuss JJ

更新日期：1980-07-14 00:00:00

abstract：:The effects of exo- and endogenous cGMP on the resting activity (RA) of afferent crista fibers were studied in isolated preparations of the statocysts of the cuttlefish Sepia officinalis and the squid Sepioteuthis lessoniana. Bath application of the membrane-permeable cGMP analogs 8-bromo-cGMP (B-cGMP) and N(2),2'-o-d...

journal_title：Brain research

authors： Tu Y,Budelmann BU

更新日期：2000-10-13 00:00:00

abstract：:Recent work in our laboratory has demonstrated that spontaneous or evoked climbing fiber inputs are associated with an increased responsiveness of Purkinje cells to mossy fiber inputs activated by natural peripheral stimuli. These experiments were designed to test the hypothesis that this increased responsiveness occu...

journal_title：Brain research

authors： Ebner TJ,Bloedel JR

更新日期：1984-08-20 00:00:00

abstract：:Two categories of large neurons--fusiform cells and giant cells--can be distinguished in the dorsal cochlear nucleus of the hamster. In the adult, these neurons are located in separate laminae in the nucleus and have distinct dendritic morphology. However, the two cell types are not distinguishable in the newborn hams...

journal_title：Brain research

authors： Schweitzer L,Cant NB

更新日期：1985-05-01 00:00:00

abstract：:Horseradish peroxidase was injected intracellularly into motoneurons responding to cutaneous stimulation of the central foot pad of the hind limb in cats. Three motoneurons were selected for detailed analysis: two excited by foot pad stimulation, and one postsynaptically inhibited by such stimulation. The overall leng...

journal_title：Brain research

authors： Egger MD,Egger LD

更新日期：1982-12-16 00:00:00

abstract：:Chemotherapy-induced pain is the most common treatment-limiting complication encountered by cancer patients receiving taxane-, vinca alkaloid- or platin-based chemotherapy. Several lines of evidence indicate that activation of pro-inflammatory cascades involving the release of cytokines including tumor necrosis factor...

journal_title：Brain research

authors： Cata JP,Weng HR,Dougherty PM

更新日期：2008-09-10 00:00:00

abstract：:The motivational effects of exclusively peripheral or central opiate receptor blockade were studied using place conditioning. Place aversions were observed with intraventricular (i.c.v.) methylnaloxone (MN) in both naive (200-1000 ng) and morphine-dependent rats (50-500 ng). Subcutaneous MN (0.03-10 mg/kg) was ineffec...

journal_title：Brain research

authors： Hand TH,Koob GF,Stinus L,Le Moal M

更新日期：1988-12-06 00:00:00

abstract：:Enkephalin immunoreactive neurons within the nucleus tractus solitarius (NTS) were found to project to the parabrachial nucleus of the cat with the use of a combination of immunohistochemistry and retrograde transport of horseradish peroxidase. Double labelled neurons were located in the medial, parvocellular and comm...

journal_title：Brain research

authors： Maley BE,Panneton WM

更新日期：1988-03-01 00:00:00

abstract：:Activation of the immune system produces psychological and physiological effects, which resemble the characteristics of depression. The present study was designed to investigate further, in rats, the similarity between the behavioral effects of immune activation and a model of depression in animals. Reduction in the p...

journal_title：Brain research

authors： Yirmiya R

更新日期：1996-03-04 00:00:00

abstract：:In synaptosomal preparations from rat cerebral cortex, ouabain-sensitive Rb+ uptake was stimulated by ethanol (20-80 mM). Based on differential sensitivity to ouabain, 80% of this Na+,K(+)-ATPase activity represented activity of the alpha 1 isozyme while 20% was due to the alpha 2 and/or alpha 3 isozymes (alpha 2/ alp...

journal_title：Brain research

authors： Foley TD,Rhoads DE

更新日期：1994-08-08 00:00:00

abstract：:The exposure of cultured rat striatal neurons to L-DOPA caused marked cell death. The L-DOPA cytotoxicity was inhibited by the addition of Mg2+ to and by the removal of Ca2+ from the culture medium, and also by the application of tetrodotoxin. Moreover, prolonged application of L-DOPA increased the glutamate content i...

journal_title：Brain research

authors： Maeda T,Cheng N,Kume T,Kaneko S,Kouchiyama H,Akaike A,Ueda M,Satoh M,Goshima Y,Misu Y

更新日期：1997-10-10 00:00:00

abstract：:Whole cell and perforated patch clamp experiments were conducted on cultured cortical rat neurones (7-21 days in vitro) in order to determine the effects of the anticonvulsant and glutamate release inhibitor Lamotrigine (10-100 microM), on CNS receptors and ion channels. The compound inhibited, indiscriminately, both ...

journal_title：Brain research

authors： Lees G,Leach MJ

更新日期：1993-05-28 00:00:00

abstract：:The mismatch negativity is an electrophysiological marker of auditory change detection in the event-related brain potential and has been proposed to reflect an automatic comparison process between an incoming stimulus and the representation of prior items in a sequence. There is evidence for two main functional subcom...

journal_title：Brain research

authors： Fuentemilla L,Marco-Pallarés J,Münte TF,Grau C

更新日期：2008-07-18 00:00:00

abstract：:The volume of nucleus HVc of the avian song system varies greatly both among and within songbird species, and is positively correlated to song complexity in many species. Moreover, the number of neurons in HVc predicts the ability of individual zebra finches to imitate song accurately. To better understand this brain/...

journal_title：Brain research

authors： Ward BC,Nordeen EJ,Nordeen KW

更新日期：2001-06-22 00:00:00