Abstract:
:The hypothalamic paraventricular nucleus is known to send projections to the dorsal medullary area where it appears to innervate the nucleus tractus solitarius and the dorsal motor nucleus of the vagus. Experiments were carried out in urethane anesthetized rats to identify single vagal motor neurons identified by antidromic invasion and to determine their response to stimulation of the paraventricular nucleus (PVN) of the hypothalamus. From the ipsilateral vagus, 26 single units were antidromically activated. Of these, the majority were unresponsive to PVN stimulation; however, 3 of these neurons demonstrated orthodromic excitation following paraventricular stimulation. These studies provide electrophysiological evidence in support of an interaction between descending paraventricular neurons and vagal motor neurons, but indicate that the majority of such vagal neurons are not influenced directly by the PVN.
journal_name
Brain Resjournal_title
Brain researchauthors
Lawrence D,Pittman QJdoi
10.1016/0006-8993(85)90399-3subject
Has Abstractpub_date
1985-04-15 00:00:00pages
158-60issue
1eissn
0006-8993issn
1872-6240pii
0006-8993(85)90399-3journal_volume
332pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract::The effects of local and global context on concurrent sound segregation were examined using a mistuned harmonic paradigm. Presented with the same sounds over three conditions, participants were asked to either categorise the incoming complex according to pitch or harmonicity (active listening) or watch a muted subtitl...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2007.10.093
更新日期:2008-01-16 00:00:00
abstract::The morphological features and distribution of luteinizing hormone-releasing hormone (LHRH)-immunoreactive cell bodies and fibers of the hypothalamic and the neighboring mesencephalic regions were studied in the normal newborn infant by immunohistochemistry. Within the hypothalamus, numerous LHRH-immunoreactive like (...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(90)90929-6
更新日期:1990-05-21 00:00:00
abstract::We have previously used organotypic cultures to study mechanisms regulating phenotypic expression of neurotransmitter characters in the brain. Our previous work indicated that nerve growth factor (NGF) specifically increased the activity of choline acetyltransferase (CAT) in striatal cholinergic interneurons. In the p...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(87)91136-x
更新日期:1987-06-02 00:00:00
abstract::Abdominal musculature participates in generating a large number of behaviors and protective reflexes, although each abdominal muscle is frequently activated differentially during particular motor responses. For example, rectus abdominis has been reported to play less of a role in respiration than other abdominal muscl...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(01)02597-5
更新日期:2001-08-31 00:00:00
abstract::Norepinephrine (NE), acting on brain adrenoceptors, plays an important role in barrel field neuronal activity and plasticity. For this reason, the distribution of alpha 1- and alpha 2-adrenoceptors in the somatosensory cortex barrel field was studied by autoradiographic techniques in rats undergoing plastic change or ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(93)90005-8
更新日期:1993-09-24 00:00:00
abstract::The present study was undertaken to confirm the dorsolateral pontomesencephalic reticular formation (an area that includes the nucleus cuneiformis (NCF) and nucleus parabrachialis (NPB)) as a sensitive site for stimulation-produced antinociception and to investigate the possibility that there are cells in this region ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(89)90171-6
更新日期:1989-04-03 00:00:00
abstract::The solubilized rat central nervous system (hypothalamic) nicotinic cholinergic receptor and the Torpedo nicotinic cholinergic receptors are immunologically similar and show greater than 60% immunologic cross-reactivity using a double-antibody technique. Antibodies to the Electrophorus and Torpedo receptors also decre...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(79)90700-5
更新日期:1979-12-14 00:00:00
abstract::Double-staining in either vibratome or paraffin sections using contrasting chromogens revealed an alpha-melanocyte-stimulating hormone (alpha-MSH)-containing cell group in the arcuate nucleus, a metorphamide-containing cell group in the paraventricular hypothalamus, and an extensive group of magnocellular perikarya in...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(88)90012-1
更新日期:1988-06-14 00:00:00
abstract::Brain and anterior pituitary growth hormone (GH), thyroid-stimulating hormone (TSH) and luteinizing hormone (LH) were measured during fetal, neonatal, and pubertal life and into adulthood. Immunoassayable GH and TSH could be found in the fetal whole brain before their detection in the fetal pituitary. Developmental pa...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0165-3806(82)90186-9
更新日期:1982-08-01 00:00:00
abstract::Intermediate filament aggregation within motor neurons is a hallmark of ALS pathogenesis. Changes to intermediate filament stoichiometry due to altered mRNA steady-state levels of NEFL, PRPH and INA is thought to drive protein aggregation, yet the exact cause of these changes is unknown. MicroRNAs (miRNAs)-master regu...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2018.10.032
更新日期:2019-03-01 00:00:00
abstract::Open field and T-maze paradigms are used to test the effects of hippocampal lesions on spatial memory in rodents. Place cells in the dorsal CA1 region of the hippocampus are known to be responsible for the formation of global place maps, while CA3 neurons respond to changes in local contexts. It is proposed here that ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2007.10.050
更新日期:2008-01-02 00:00:00
abstract::The subunit composition of α-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate receptors (AMPARs) is an important determinant of AMPAR biophysical properties and trafficking. To date, AMPAR subunit composition has been quantitatively evaluated only for the hippocampus, where different experimental approaches have yield...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2010.10.016
更新日期:2011-01-07 00:00:00
abstract::The central type benzodiazepine receptor (BDZr), an allosteric modulatory site of the GABAA receptor-anion channel, has been shown in vitro to respond to drugs with positive efficacy (agonists), zero efficacy (competitive antagonists) and drugs with negative efficacy (inverse agonists). However, this general concept o...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(91)90131-e
更新日期:1991-08-23 00:00:00
abstract::Recent findings have shown that systemic morphine increases extracellular dopamine (DA), dihydroxyphenylacetic acid (DOPAC), homovanillic acid (HVA), ascorbic acid (AA) and uric acid concentrations in the striatum of freely moving rats. The morphine-induced increase in DA oxidative metabolism is highly correlated with...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(98)00371-0
更新日期:1998-06-22 00:00:00
abstract::Rabbits passively oscillated in the horizontal plane with a free hand tended to stabilize their head in space (re: earth-fixed surroundings) by moving the head on the trunk (neck angular deviation, NAD) opposite the passively imposed body rotation. The gain (NAD/body rotation) of head stabilization varied from 0.0 to ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(81)90346-2
更新日期:1981-02-02 00:00:00
abstract::Extracellular action potentials were recorded from 691 neurons in the ventromedial hypothalamus (VMH) of urethane anesthetized female rats under acute and chronic sham-operated and hyperprolactinemic conditions. Hyperprolactinemia was produced by transplanting pituitaries under the kidney capsules. Neuronal excitabili...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(85)90864-9
更新日期:1985-11-04 00:00:00
abstract::The relationship between the dorsal raphe neurons projecting to the caudate-putamen and those projecting to the substantia nigra was investigated using a fluorescent retrograde double labeling technique in the rat. The majority of the dorsal raphe neurons projecting to the substantia nigra were found to project also t...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90250-4
更新日期:1980-03-17 00:00:00
abstract::Pain resulting from peripheral nerve injury, characterised by ongoing pain, hyperalgesia and allodynia arises from peripheral and central processes. Here, we studied the potential role of central facilitations in nerve injury by investigating the effect of blocking the excitatory 5HT3 receptor with ondansetron. 5HT3 r...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2004.05.108
更新日期:2004-09-03 00:00:00
abstract::Anticipation of an unavoidable painful stimulation, i.e. anticipation stress, induces analgesia. This analgesia may result from activation of the endogenous opioid peptide system as it is blocked by naloxone. The present paper characterizes the anticipation stress further by following the kinetics of the analgesia ris...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(89)91674-0
更新日期:1989-12-04 00:00:00
abstract::Binding activities specific for each of [3H]prostaglandin (PG) D2, E2 and F2 alpha were detected in the P2 fraction of the human brain homogenates. The bindings were time-dependent, saturable and of high affinity; Kd values were 30 nM for all the PG bindings. Regional distribution of these binding activities was deter...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(85)91358-7
更新日期:1985-09-02 00:00:00
abstract::Small reductions in temperature have been shown to improve neurologic recovery after ischemia. We have examined the effect of temperature on biochemical and physiological changes during hypoxia using rat hippocampal slices as a model system. The postsynaptic population spike recorded from the CA1 pyramidal cell region...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(99)01944-7
更新日期:1999-10-09 00:00:00
abstract::The role of calcium and protein kinases in rhythmic activity induced by muscarinic receptor activation in the CA1 area in rat hippocampal slices was investigated. Extracellular recording showed that carbachol (20 microM) induced synchronized field potential activity with a dominant frequency of 7.39+/-0.68 Hz. Pretrea...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(00)02331-3
更新日期:2000-07-28 00:00:00
abstract::Benzodiazepine binding sites are present on gamma-aminobutyric acid (GABA) receptors in hippocampal neurons. Diazepam is known to potentiate the amplitude and prolong the decay of GABA(A) receptor-mediated inhibitory postsynaptic currents (IPSCs). In this study, benzodiazepine involvement in long-term potentiation (LT...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2005.09.008
更新日期:2005-11-16 00:00:00
abstract::Modulation of gamma-aminobutyric acid (GABA)-mediated inhibition, and glutamate-mediated excitation by highly selective mu and delta opioid agonists was studied using intracellular recordings of CA1 pyramidal neuron synaptic responses in superfused hippocampal slices. Equimolar concentrations of the selective mu agoni...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(92)91312-3
更新日期:1992-10-16 00:00:00
abstract::Repeated administration of subconvulsant doses of lidocaine or cocaine results in the development of an increased susceptibility to seizures induced by the two drugs (pharmacological kindling). It has been hypothesized that the local anesthetic properties of cocaine are responsible for its convulsant and epileptogenic...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(91)90628-9
更新日期:1991-10-25 00:00:00
abstract::The roles of the dorsal and ventral hippocampus in fear and memory are unclear. This study examined the effects of temporary inactivation of the dorsal or ventral hippocampus on unconditioned and conditioned fear, using the shock-probe test. In Experiment 1, rats received either dorsal or ventral hippocampal infusions...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2008.11.041
更新日期:2009-01-28 00:00:00
abstract::The locus coeruleus of the adult albino rat is a clearly delimited nucleus in Nissl-stained preparations. It is surrounded by an extensive, relatively neuron-free neuropil which is not stained in reduced silver and Luxol fast blue preparations. Most if not all locus coeruleus neurons contain the enzyme dopamine-beta-h...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(76)90207-9
更新日期:1976-06-25 00:00:00
abstract::In the present study, we used a repeated restraint stress animal model to observe the changes in the expression of brain-derived neurotrophic factor (BDNF) and B cell lymphoma protein-2 (Bcl-2) in hippocampal neurons of rats, monitored the time course of the expression over 3 weeks post-stress period, and examined the...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2004.06.089
更新日期:2004-10-29 00:00:00
abstract::The distribution of radioactivity after injection of [3H]testosterone was studied in the forebrain of adult mice by thaw-mount autoradiography. Nuclear labeling was high in neurons in the dorsal part of the medial nucleus of the amygdala and in the dorsocaudal part of the bed nucleus of the stria terminalis. Low nucle...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(86)90630-x
更新日期:1986-11-12 00:00:00
abstract::A site-specific antibody against the principal gap junctional protein in heart (connexin 43) was used to determine immunohistochemically the cellular localization of this protein in rat brain. Structures labelled with the antibody included gap junctional membranes between glial, ependymal, pial and arachnoid cells as ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(90)90415-8
更新日期:1990-02-05 00:00:00