Topographic coding of odorant quality is maintained at different concentrations in the salamander olfactory epithelium.

Abstract:

:In a recent study in the tiger salamander, Ambystoma tigrinum, were demonstrated topographic patterns of responsivity across the olfactory epithelium which were characteristic for each odorant. The present study was initiated to investigate whether these patterns remain constant when odorant concentration is varied. Odorant-induced electro- olfactograms were recorded from at least 12 sites on each epithelium. The odorants used were pinene, amyl acetate and propanol. Each epithelium was tested with one odorant, delivered at 3 concentrations. For comparison between animals, the epithelia were divided into 3 regions with at least 4 recording sites per region. An analysis of variance model was used to study odorants, concentrations, regions and animals. Odorant-induced regional patterns in responsivity were similar across all concentrations. In particular, the region of highest responsivity at one concentration was the region of highest responsivity at all concentrations. It is concluded that topographic patterns of receptor cell responses may reflect an underlying genetic component in the distribution of receptor cells. This distribution is related to two aspects of receptor cell responses: responsivity to particular odorants (Fig. 4) and general responsivity to all odorants (Fig. 5).

journal_name

Brain Res

journal_title

Brain research

authors

Mackay-Sim A,Shaman P

doi

10.1016/0006-8993(84)90562-6

subject

Has Abstract

pub_date

1984-04-16 00:00:00

pages

207-16

issue

2

eissn

0006-8993

issn

1872-6240

pii

0006-8993(84)90562-6

journal_volume

297

pub_type

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