Abstract：
:Following the administration of horseradish peroxidase (HRP) in the middle or lower cervical cord segments of neonatal (1-10 days), developing (15-20 days) and mature (2-4 months) albino rats, labeled pyramidal neurons were found in layer V of the cerebral cortex. They formed one continuous band of labeled neurons in the frontal and parietal isocortex in neonatal animals. The band began close to the frontal pole and extended distally for about 3600 microns. Mediolaterally the lateral limit of the band was at the dorsal lip of the rhinal sulcus. Neurons in the 'shoulder' region along the medial surface of the cerebral hemisphere were also labeled. As the animals increased in age it became increasingly more difficult to label the pyramidal neurons in the parietal band. The band appeared broken and discontinuous in the parietal region in the 15-day-old rats. In the 20-day-old and mature rats the labeled neurons appeared in two bands, a dorsolateral one and a parietal one, the two being separated by a variable gap of cortex where practically no or very few neurons were labeled. Labeled neurons in the 'shoulder' region were distinctly seen only in the rostral region of the frontal isocortex in older animals. Following the administration of HRP in lumbosacral cord segments, no labeled layer V pyramidal neurons were seen in the 2-day-old rats, but they were seen to form one continuous band in the dorsolateral part of the cerebral cortex in rats aged 5 days postnatally and older. They appeared in a caudo-rostral sequence, with neurons in the caudal part of the cerebral cortex projecting to the more caudal cord segments and those in the frontal part to the more rostral cord segments. Mediolaterally the band was about 2 mm wide. Neurons in the 'shoulder' region were infrequently seen in neonatal and developing animals.
journal_name
Brain Resjournal_title
Brain researchauthors
Leong SKdoi
10.1016/0006-8993(83)91327-6subject
Has Abstractpub_date
1983-04-11 00:00:00pages
1-9issue
1eissn
0006-8993issn
1872-6240pii
0006-8993(83)91327-6journal_volume
265pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract：:Magnetic resonance spectroscopy (MRS) has demonstrated age-related changes in brain metabolites that may underlie micro-structural brain changes, but few studies have examined their relationship with cognitive decline. We performed a cross-sectional study of brain metabolism and cognitive function in 82 healthy adults...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2007.06.027
更新日期：2007-08-20 00:00:00
abstract：:This study evaluated the hypothesis that the dorsal motor nucleus (DMN) of the brainstem may mediate the ulcerogenic and acid-stimulatory effects of thyrotropin-releasing hormone (TRH) in rats. To accomplish this, intra-DMN microinjections of TRH (50 and 500 ng) were performed and their effects on acid secretion and g...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(88)90295-8
更新日期：1988-08-30 00:00:00
abstract：:Recordings have been made from 162 pyramidal tract neurones which discharged bursts of nerve impulses in characteristic temporal association with performances of a stereotyped motor task by monkeys. Clinical evaluation of the relationship between discharges of the neurones and free movement led to the view that each c...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(75)90507-7
更新日期：1975-11-07 00:00:00
abstract：:One optic nerve of mature goldfish was crushed in the orbit and allowed to regenerate. During regeneration impulse activity was eliminated by periodic intraocular injections of tetrodotoxin (TTX). At 32-104 days, the retinotopography of the retinotectal projection was measured autoradiographically by intraocular [3H]p...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0165-3806(83)90068-8
更新日期：1983-02-01 00:00:00
abstract：:The effects of target and non-target cells on the growth and function of intrastriatal grafts of mesencephalic dopamine neurons have been studied in rats with unilateral 6-hydroxydopamine-induced lesions of the nigrostriatal dopamine pathway. Cell suspensions of ventral mesencephalon from 14-15-day-old rat fetuses (ri...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0165-3806(86)90174-4
更新日期：1986-01-01 00:00:00
abstract：:This study explores the longitudinal assessment of visual evoked potentials (VEPs) in the rabbit as a method for defining factors underlying functional and structural changes associated with optic neuritis and the inflammatory demyelinating diseases. In rabbits with experimental autoimmune encephalomyelitis (EAE) indu...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(88)90557-4
更新日期：1988-10-18 00:00:00
abstract：:We compared the laminar location and morphology of superior colliculus cells projecting to the dorsal and ventral lateral geniculate nuclei (LGd, LGv), the pretectum (PT), the parabigeminal nucleus (Pb), and nucleus lateralis posterior (LP) in the ground squirrel Spermophilus tridecemlineatus. Horseradish peroxidase w...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(87)90432-x
更新日期：1987-11-17 00:00:00
abstract：:The effects of postnatal thyroidectomy (on day 8 after birth) and 131I treatment (on day 10) on the development of the vomeronasal organ (VO) has been studied In the rat. Thyroidectomized rats showed decrements in the overall VO volume, volume of the neurosensorial epithelium, neuronal population and nuclear size of n...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0165-3806(82)90159-6
更新日期：1982-10-01 00:00:00
abstract：:Light microscopic double labeling immunocytochemistry for vasoactive intestinal peptide (VIP) and gonadotrophin-releasing hormone (GnRH) was carried out on the hypothalami of male and female rats. It was found that the number of VIP boutons that terminate on GnRH neurons and the percentage of GnRH neurons contacted by...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(98)00208-x
更新日期：1998-06-08 00:00:00
abstract：:This study investigates the reanalysis processes as a consequence of conflict between incompatible sentential representations in sentence comprehension. Using the event-related potential (ERP) technique, we examined the situation in which the sentential representation built upon world knowledge (i.e., the plausibility...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2008.01.090
更新日期：2008-04-08 00:00:00
abstract：:Cytochemistry was used to examine the distribution of two pathways of utilization of hydrogen (Type I and Type II H) generated by glucose-6-phosphate dehydrogenase (G6PD) in circumventricular organs (CVOs) and the hypothalamo-neurohypophysial system in cryostat sections of rat brain. Type I H is defined as that portio...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(84)91306-4
更新日期：1984-02-27 00:00:00
abstract：:The central nervous system (CNS) in adult mammals loses the ability to regenerate after injury. Although electrical stimulation (ES) has been shown to promote neural regeneration, the underlying mechanisms by which ES enhances CNS regeneration remain elusive. The aim of the present study was to investigate the effect ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2012.08.041
更新日期：2012-10-22 00:00:00
abstract：:Individuals are found to have better recall for self-referent information than other types of information. However, attribution research has shown that self-reference is highly correlated with emotional valence. The present study attempted to identify and separate the processing of self-reference and emotional valence...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2007.03.049
更新日期：2007-06-04 00:00:00
abstract：:The prefrontal cortex (PFC) plays a central role in preparatory and anticipatory attentional processes. To investigate whether subregions of the PFC play differential roles in these processes we investigated the effect of focal lesions to either lateral prefrontal (lateral PFC; n=11) or orbitofrontal cortex (OFC; n=13...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2013.06.017
更新日期：2013-08-21 00:00:00
abstract：:For the evaluation of glutamatergic and GABAergic transmission during seizures, rat hippocampal CA1 and CA3 areas were separately assessed by brain microdialysis, and extracelluar glutamate and GABA were measured through the course of the seizures after a systemic administration of kainic acid (KA). The generalized co...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(98)00507-1
更新日期：1998-07-27 00:00:00
abstract：:The effects of 4 anaesthetics, halothane, alpha-chloralose, chloral hydrate and pentobarbitone, on rat striatal extracellular dihydroxyphenylacetic acid (DOPAC) levels were determined using in vivo voltammetry. Stable baseline levels of DOPAC were maintained under halothane/N2O and alpha-chloralose while the extracell...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)90270-2
更新日期：1986-07-30 00:00:00
abstract：:'Feedback' signals from mammalian extrastriate visual cortices are reported to exert primarily an excitatory influence on the classical receptive field (CRF) of neurons in the primary visual cortex (V1). However, given the much larger CRFs of neurons in extrastriate visual cortices it is not yet understood how feedbac...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2010.02.069
更新日期：2010-04-30 00:00:00
abstract：:In the sea hare, Aplysia californica, consummatory feeding behavior is selectively abolished by bilateral crushes of the cerebral-buccal connectives and recovers by postlesion day 13. Recovered biting responses are initially weak and increase in magnitude gradually with time. The lesions do not affect appetitive feedi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(92)91217-3
更新日期：1992-07-10 00:00:00
abstract：:The neural connections from the ventral pallidum (VP) through the mediodorsal nucleus of the thalamus (MD) to the medial prefrontal cortex (MPC) were investigated. Extracellular recordings were made from 219 neurons in the medial and lateral portions of the MD and the VP and the MPC were stimulated. The most frequent ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)90811-x
更新日期：1985-10-07 00:00:00
abstract：:Murine spinal cord primary mixed cultures were treated with the respiratory inhibitor, rotenone, to mimic hypoxic conditions. Under these conditions neurons rapidly underwent oncosis (necrosis) with a complete loss in viability occurring within 260 min; however, astrocytes, which accounted for most of the cell populat...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(99)01086-0
更新日期：1999-03-13 00:00:00
abstract：:In the present study, uptake of glutamine by rat cerebellar granule cells, a predominantly glutamatergic nerve cell population, has been investigated. Glutamine is taken up by granule cells via at least three transport systems, A, ASC and L. The L-type low affinity system (K(m) = 2.6 mM) is the major transport system ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(97)00139-x
更新日期：1997-05-16 00:00:00
abstract：:The radioprotective thiophosphate S-2(3 amino-propyl-amino) phosphorothioic acid (WR 2721) induced an early reduction of striatal acetylcholinesterase activity followed by an increase, when intraperitoneally injected to rats, although it does not cross the blood-brain barrier. These results were obtained using an orig...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)90788-o
更新日期：1993-04-09 00:00:00
abstract：:Previous studies in our laboratory using rat brain tissue have shown that neuropeptide Y (NPY) can enhance NMDA- and potassium-stimulated dopamine release from various brain regions and that this enhancement is reversed by sigma (sigma) receptor antagonists. In the current study, we sought to determine whether SH-SY5Y...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(00)02722-0
更新日期：2000-09-22 00:00:00
abstract：:Compound action potential recording techniques were used to investigate the time- and frequency-dependent effects of 4-aminopyridine (4-AP) and tetraethylammonium (TEA) on large diameter, fast conducting (t1) and medium diameter, middle conducting (t2) optic tract axons in anesthetized hooded rats. Single-pulse studie...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(89)91102-5
更新日期：1989-10-02 00:00:00
abstract：:By the use of anti-omega-CTx antibodies in indirect immunofluorescence we demonstrated the presence of omega-CTx binding sites in the presynaptic compartment of frog nerve-muscle preparations. The images we obtained indicate that omega-CTx-sensitive channels are clustered at discrete sites corresponding in distributio...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(91)90981-z
更新日期：1991-05-03 00:00:00
abstract：:Using cervical sympathectomized and immobilized rabbits, the relationship between the luminance intensity and the magnitude of the response in pupillo-constrictor units of the ciliary nerve was investigated. It was revealed that the intensity--response relationship of the units closely resembled that of retinal recept...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(80)90787-8
更新日期：1980-11-10 00:00:00
abstract：:Amino acid uptake by slices of brain is greatly diminished by incubation of the slices in glucose-free media. Uptake can be restored by the addition of a number of substrates, e.g., lactate, citrate, or oxaloacetate. The mixture of succinate, malate, and pyruvate (SMP, 20, 5, and mM) restored amino acid uptake better ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(77)90524-8
更新日期：1977-08-12 00:00:00
abstract：:In humans and many other mammalian species, the behavioural consequences of a cortical lesion tend to be milder when it occurs early in life, and there is evidence that an important factor contributing to the behavioural sparing in the young is the formation of new thalamo-cortical connections by thalamic neurons init...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2007.05.063
更新日期：2007-09-05 00:00:00
abstract：:The central nucleus of the amygdala (CEA) is selectively involved in the passive component of the behavioral (immobility) and the accompanying parasympathetic response during conditioned, stressful environmental challenges. Vasopressinergic mechanisms in the brain seem to play a role in these stress responses. The eff...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(92)91529-n
更新日期：1992-11-20 00:00:00
abstract：:Facilitation of cerebellorubral transmission was illustrated in nembutalized cats on paired stimulation of the cerebellar nucleus interpositus by an example of monosynaptic EPSPs of the rubrospinal neurons. It was found that the facilitation stated is not determined by the change in the presynaptic volley of impulses....
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(87)90334-9
更新日期：1987-05-05 00:00:00
