Abstract：
:The radioprotective thiophosphate S-2(3 amino-propyl-amino) phosphorothioic acid (WR 2721) induced an early reduction of striatal acetylcholinesterase activity followed by an increase, when intraperitoneally injected to rats, although it does not cross the blood-brain barrier. These results were obtained using an original technique which allows the measurements in the same animal for several days. Transient general oxidative metabolism inhibition might affect the extra-cellular enzyme amount or its activity.
journal_name
Brain Resjournal_title
Brain researchauthors
Clarençon D,Galonnier M,Testylier G,Fatôme Mdoi
10.1016/0006-8993(93)90788-osubject
Has Abstractpub_date
1993-04-09 00:00:00pages
155-8issue
1eissn
0006-8993issn
1872-6240pii
0006-8993(93)90788-Ojournal_volume
608pub_type
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