Opiate receptor binding in the brain of the hypertensive rat.

Abstract:

:Experimental and genetic hypertension in male rate is accompanied by a lower specific [3H]naloxone binding in the dorsal horn of the spinal cord, and in the hippocampus as compared to controls. Rats which are genetically resistant to hypertensive stimuli have a higher specific [3H]naloxone binding in the nucleus tractus solitarius and lower opiate receptor binding in the dorsal horn. Together with previous studies which demonstrated a correlation between blood pressure and pain sensitivity, these results support the notion that specific brain loci participate in co-regulation of pain perception and blood pressure.

journal_name

Brain Res

journal_title

Brain research

authors

Zamir N,Segal M,Simantov R

doi

10.1016/0006-8993(81)91265-8

subject

Has Abstract

pub_date

1981-05-25 00:00:00

pages

217-22

issue

1

eissn

0006-8993

issn

1872-6240

pii

0006-8993(81)91265-8

journal_volume

213

pub_type

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