Abstract：
:During the early postnatal development of the rat large numbers of pyramidal tract neurons are present in layer V of the occipital cortex, but by the end of the third postnatal week the distribution of pyramidal tract neurons becomes restricted to the more rostral cortical areas. This restriction is brought about by selective collateral elimination rather than by cell death. We have found, by using retrogradely transported fluorescent dyes as either short-term or long-term markers, that occipital cortical neurons which had transiently extended pyramidal tract axons maintain subcortical axonal connections to either the superior colliculus or the pons, and, at least in the case of the corticotectal projection, that the maintained collateral is present prior to the elimination of the transient pyramidal tract collateral. Further, it appears that at no time during postnatal development do the occipital pyramidal tract neurons form either callosal or ipsilateral cortico-cortical collaterals. Thus in the early postnatal occipital cortex the neurons which project through the pyramidal tract constitute a population of cells which is separate from neurons which make cortico-cortical connections, but which largely overlaps with the population of corticotectal and corticopontine neurons.
journal_name
Brain Resjournal_title
Brain researchauthors
O'Leary DD,Stanfield BBdoi
10.1016/0006-8993(85)90661-4subject
Has Abstractpub_date
1985-06-17 00:00:00pages
326-33issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(85)90661-4journal_volume
336pub_type
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