Sensitivity of ERG components from dark-adapted goldfish retinas treated with APB.

Abstract:

:The electroretinogram (ERG) of the dark-adapted goldfish was examined before and after intravitreal injection of DL-2-amino-4-phosphonobutyric acid (APB). APB abolished the b-wave and decreased absolute sensitivity of the remaining waveform, which was composed of a vitreal-negative component followed by a vitreal-positive component. The sensitivity, time course and amplitude of these components differed from ERGs obtained from animals treated with sodium aspartate. Spectral sensitivity of both post-APB components closely resembled that of the normal dark-adapted b-wave. The results suggest that APB does not act selectively on any particular class of photoreceptors or photoreceptor pathways in the dark-adapted goldfish retina.

journal_name

Brain Res

journal_title

Brain research

authors

DeMarco PJ Jr,Powers MK

doi

10.1016/0006-8993(89)91194-3

subject

Has Abstract

pub_date

1989-03-20 00:00:00

pages

317-23

issue

2

eissn

0006-8993

issn

1872-6240

pii

0006-8993(89)91194-3

journal_volume

482

pub_type

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