Abstract:
:The electroretinogram (ERG) of the dark-adapted goldfish was examined before and after intravitreal injection of DL-2-amino-4-phosphonobutyric acid (APB). APB abolished the b-wave and decreased absolute sensitivity of the remaining waveform, which was composed of a vitreal-negative component followed by a vitreal-positive component. The sensitivity, time course and amplitude of these components differed from ERGs obtained from animals treated with sodium aspartate. Spectral sensitivity of both post-APB components closely resembled that of the normal dark-adapted b-wave. The results suggest that APB does not act selectively on any particular class of photoreceptors or photoreceptor pathways in the dark-adapted goldfish retina.
journal_name
Brain Resjournal_title
Brain researchauthors
DeMarco PJ Jr,Powers MKdoi
10.1016/0006-8993(89)91194-3subject
Has Abstractpub_date
1989-03-20 00:00:00pages
317-23issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(89)91194-3journal_volume
482pub_type
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