Abstract：
:Acute swim stress of mice produces increases in the density of high and low affinity binding sites in the brain for the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), together with analgesia as measured by an increase in tail flick latency. Apparent tolerance develops in repeated swimming with analgesia and GABA binding returning towards control levels. The time course of analgesia and increases GABA binding following a single swim are also similar. Acute swim stress does not alter diazepam binding. GABA systems may be important in analgesia and in responses to environmental stress.
journal_name
Brain Resjournal_title
Brain researchauthors
Skerritt JH,Trisdikoon P,Johnston GAdoi
10.1016/0006-8993(81)90524-2subject
Has Abstractpub_date
1981-06-29 00:00:00pages
398-403issue
1-2eissn
0006-8993issn
1872-6240pii
0006-8993(81)90524-2journal_volume
215pub_type
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