Abstract:
:Using a specific antibody against each of the 4 catecholamine-synthesizing enzymes, dopamine or serotonin, we compared the localization of these substances in rat and mouse spinal cord with two kinds of fixative, such as paraformaldehyde and glutaraldehyde, and two types of sectioning technique, i.e. cryostat and microslicer. In this study, we demonstrated aromatic L-amino acid decarboxylase (AADC)-like immunoreactivity (LI) in cerebrospinal fluid (CSF)-contacting neurons for the first time in the mouse. These cells and some AADC-immunoreactive cells localized outside the subependymal layer of mouse and rat spinal cord did not show tyrosine hydroxylase-, serotonin- and dopamine-LI with and without colchicine treatment.
journal_name
Brain Resjournal_title
Brain researchauthors
Nagatsu I,Sakai M,Yoshida M,Nagatsu Tdoi
10.1016/0006-8993(88)90202-8subject
Has Abstractpub_date
1988-12-13 00:00:00pages
91-102issue
1eissn
0006-8993issn
1872-6240pii
0006-8993(88)90202-8journal_volume
475pub_type
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