Effects of inflammation produced by chronic lipopolysaccharide administration on the survival of hypocretin neurons and sleep.

abstract：:The short term effects of spinal cord hemisection on protein synthesis in the Cebus monkey were studied by measuring the uptake of [3H]lysine into the trichloroacetic acid (TCA) precipitable and non-precipitable fractions of spinal cord. Animals were sacrificed 3, 6, or 13 days after hemisection. Two normal animals an...

journal_title：Brain research

authors： Wells MR,Bernstein JJ

更新日期：1976-07-23 00:00:00

abstract：:The ultrastructure of the dorsal column nucleus (DCN) has been investigated at the level of the obex region in normal and experimental toads. Large 'isolated' neurons (greater than 20 micrometer) and clusters of small neurons (less than 20 micrometer) have been identified in this region. Synaptic profiles have been cl...

journal_title：Brain research

authors： Corvaja N,Pellegrini M,Buisseret-Delmas C

更新日期：1978-03-10 00:00:00

abstract：:A transplantable mouse testicular teratoma (OTT 6050) which displays a spectrum of neuroepithelial differentiation was evaluated biochemically for concentrations of cyclic AMP (cAMP), serotonin (5-HT), and enzymes involved in the metabolism of the biogenic amines and acetylcholine. These values were compared between t...

journal_title：Brain research

authors： Orenberg EK,Vandenberg SR,Barchas JD,Herman MM

更新日期：1976-01-16 00:00:00

abstract：:Extracellular recordings were carried out in the primary visual cortex of behaving monkeys. Neurons were activated by moving a visual stimulus on their receptive fields during periods of steady fixation and by moving their receptive fields (smooth pursuit eye movements) on a motionless visual stimulus. Regarding non-o...

journal_title：Brain research

authors： Galletti C,Squatrito S,Battaglini PP,Maioli MG

更新日期：1983-01-31 00:00:00

abstract：:Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) is a potent neuroexcitatory compound which acts at the quisqualate class of excitatory amino acid receptors. In this study we describe the pharmacological characteristics and anatomical distribution of [3H]AMPA binding sites in rat brain using quantitativ...

journal_title：Brain research

authors： Monaghan DT,Yao D,Cotman CW

更新日期：1984-12-17 00:00:00

abstract：:Behavioral stress is likely to contribute to the development of hypertension in susceptible individuals. We reported that hemodynamic response patterns to acute startle vary and that those patterns predict the predisposition of rats to sustained stress-induced elevations in arterial pressure. Since considerable eviden...

journal_title：Brain research

authors： Tan Y,Gan Q,Knuepfer MM

更新日期：2003-04-04 00:00:00

abstract：:Several studies have reported transient expression of tyrosine hydroxylase in a subpopulation of neurons in the bed nucleus of stria terminalis of preadolescent rats. The tyrosine hydroxylase immunoreactive (TH) neurons, which are of small to medium size and often display a typical bipolar configuration, are confined ...

journal_title：Brain research

authors： Beltramino CA,Forbes MS,Swanson DJ,Alheid GF,Heimer L

更新日期：1996-01-08 00:00:00

abstract：:Electrophysiological studies have suggested that the excitatory actions of opioids in the hippocampal formation are mediated by inhibition of interneurons containing GABA; however, an anatomical basis for this interaction has never been established. Thus, we sought to determine the relationship between leu-enkephalin ...

journal_title：Brain research

authors： Commons KG,Milner TA

更新日期：1996-06-10 00:00:00

abstract：:Two-day-old rats were pretreated with 50 mg/kg of capsaicin. After 3--4 months, specific binding of [3H]muscimol and [3H]strychnine was measured in membrane preparations from dorsal spinal cord. A 20-30% decrease of the number of [3H]muscimol binding sites was observed after capsaicin treatment. In contrast, [3H]stryc...

journal_title：Brain research

authors： Singer E,Placheta P

更新日期：1980-12-08 00:00:00

abstract：:This study shows that permanent cell lines can be established from rat and mouse brain by direct tissue culture methodology without the aid of exogenous chemical or viral transforming agents. These cells were derived from specific areas of the brain, such as the cerebellum and hippocampus, at chosen times during fetal...

journal_title：Brain research

authors： Bulloch K,Stallcup WB,Cohn M

更新日期：1977-10-21 00:00:00

abstract：:Expression of the immediate-early gene c-fos, a marker of neuronal activation, was employed to localize brainstem neuronal populations functionally related to the expiration reflex (ER). Twelve spontaneously breathing, non-decerebrate, pentobarbital anesthetized cats were used. The level of Fos-like immunoreactivity (...

journal_title：Brain research

authors： Poliacek I,Halasova E,Jakus J,Murin P,Barani H,Stransky A,Bolser DC

更新日期：2007-12-12 00:00:00

abstract：:In order to explore the anatomical nature of the inhibitory GABAergic control of cerebral serotonergic neurons exerted at the level of the anterior raphé cells in the rat, we have studied the effect of GABA agonist agents (given systemically or infused locally into the raphé dorsalis or medianus) on cerebral 5-hydroxy...

journal_title：Brain research

authors： Nishikawa T,Scatton B

更新日期：1985-04-01 00:00:00

abstract：:The development of spontaneous activity in response to morphine administration was studied at different postnatal ages in C57BL/6 mice. Morphine induced hyperactivity at all ages except in 3-week-old mice, in which a catatonic effect is evident. The results indicate that the neurophysiological and inhibitory systems r...

journal_title：Brain research

authors： Filibeck U,Castellano C,Oliverio A

更新日期：1981-11-01 00:00:00

abstract：:In the previous study, we reported increased NOS expression in the astrocytes in the spinal cord of the transgenic mice that are used as ALS animal model. In the present study, we performed immunocytochemical studies to investigate the changes of nitrotyrosine-immunoreactivity in the brains of the transgenic mice, and...

journal_title：Brain research

authors： Cha CI,Chung YH,Shin CM,Shin DH,Kim YS,Gurney ME,Lee KW

更新日期：2000-01-17 00:00:00

abstract：:Serotoninergic transmission is implicated in the photic and non-photic regulation of circadian rhythms. 5-HT (1-100 microM), carboxamidotryptamine (5-CT 0.1-10 microM) and (+)-8-hydroxy-dipropylaminotetraline (8-OH-DPAT, 1-30 microM) dose-dependently activated an outward current (5-100 pA) in 30% of neurons voltage-cl...

journal_title：Brain research

authors： Jiang ZG,Teshima K,Yang Y,Yoshioka T,Allen CN

更新日期：2000-06-02 00:00:00

abstract：:Hyperprolinemia type II is an autosomal recessive disorder caused by the severe deficiency of delta(1)-pyrroline-5-carboxylate dehydrogenase activity leading to tissue accumulation of proline (Pro). Most patients detected so far show neurological manifestations including epilepsy and mental retardation, whose pathophy...

journal_title：Brain research

authors： Delwing D,Bavaresco CS,Chiarani F,Wannmacher CM,Wajner M,Dutra-Filho CS,de Souza Wyse AT

更新日期：2003-11-21 00:00:00

abstract：:Dexmedetomidine (Dex) has the neuroprotective effect on cerebral ischemia-reperfusion injury (CIRI). But the mechanism is not yet clear. In this study, we established a model of middle cerebral artery occlusion (MCAO) and treated primary cortical neurons with oxygen glucose deprivation (OGD), followed by Dex treatment...

journal_title：Brain research

authors： Liu C,Fu Q,Mu R,Wang F,Zhou C,Zhang L,Yu B,Zhang Y,Fang T,Tian F

更新日期：2018-12-15 00:00:00

abstract：:The role of mu opioid receptors in the nucleus raphe dorsalis (DR) in the control of apomorphine-induced aggression was studied in rats. Administration in the DR of a selective mu opioid receptor agonist, (D-Ala2,N-Me-Phe4,Gly5-ol)-enkephalin (DAGO), in doses ranging from 0.01 to 1 microgram/0.5 microliter, dose-depen...

journal_title：Brain research

authors： Giraud O,Cervo L,Grignaschi G,Samanin R

更新日期：1989-05-29 00:00:00

abstract：:The quantitative autoradiographic method with L-(35S)methionine was used to determine the effects of 1-acute (4h) and 2-chronic (14 days) immobilization stress followed by one week of recovery. Acute stress induced a significant decrease in methionine incorporation into proteins in 17 of the 35 brain structures examin...

journal_title：Brain research

authors： Giaume M,Grange E,Baubet V,Gay N,Sermet E,Sarda N,Bobillier P

更新日期：1995-03-27 00:00:00

abstract：:The purpose of this study was to identify the functional fields activated in relation to the self-paced proximal and distal arm movements. The regional cerebral blood flow (rCBF) was measured with positron emission tomography (PET) and 15O-labelled H2O (H2(15)O) in eight healthy subjects. All subjects performed the fo...

journal_title：Brain research

authors： Kawashima R,Itoh H,Ono S,Satoh K,Furumoto S,Gotoh R,Koyama M,Yoshioka S,Takahashi T,Takahashi K,Yanagisawa T,Fukuda H

更新日期：1996-04-15 00:00:00

abstract：:Previous research with deafferented subjects suggests that efference copy can be used to update limb position. However, the contributions of efference copy to limb localization are currently unclear. We examined the performance of JDY, a woman with severe, longstanding proprioceptive deficits from a sensory peripheral...

journal_title：Brain research

authors： Medina J,Jax SA,Brown MJ,Coslett HB

更新日期：2010-10-08 00:00:00

abstract：:Preganglionic sympathetic neurons were labelled by retrograde transport of horseradish peroxidase, while catecholamine axon varicosities were marked by the uptake of 5-hydroxydopamine in the intermediolateral nucleus of the rat. The direct synaptic contacts from the catecholamine axons to the preganglionic sympathetic...

journal_title：Brain research

authors： Chiba T,Masuko S

更新日期：1986-08-20 00:00:00

abstract：:Lithium is detected in the mouse brain with the aid of a (n,alpha) nuclear reaction. The resolving power is of a few micron. The detection efficiency is estimated in a first series of experiments with brain sections of progressively increasing thickness. This allows us to make the microlocation of lithium in the brain...

journal_title：Brain research

authors： Thellier M,Heurteaux C,Wissocq JC

更新日期：1980-10-13 00:00:00

abstract：:The influence of extracellular sinusoidal electric fields on the amplitude of population spikes evoked by single test pulses in excitatory pathways to CA1 pyramidal neurons was studied in rat hippocampal slices. The fields in the tissue were of the order of EEG gradients. Stimulation at 5 Hz, a frequency representativ...

journal_title：Brain research

authors： Bawin SM,Sheppard AR,Mahoney MD,Adey WR

更新日期：1984-12-10 00:00:00

abstract：:Numerous studies have suggested that nitric oxide (NO) in the nucleus tractus solitarii (NTS) participates in modulating cardiovascular function. Nitric oxide synthase (NOS), the enzyme responsible for synthesis of NO, exists in 3 isoforms: endothelial NOS (eNOS), neuronal NOS (nNOS), and inducible NOS (iNOS). Althoug...

journal_title：Brain research

authors： Lin LH,Taktakishvili O,Talman WT

更新日期：2007-09-26 00:00:00

abstract：:Rat hippocampal slices were incubated with [3H]uridine in vitro to analyze the metabolism of nuclear RNA and the RNA precursor fractions. Labeling of total nuclear RNA was linear for 4 h of incubation and proportional to the concentration of labeled uridine in the incubation medium. Addition of 3.5 X 10(-8) M corticos...

journal_title：Brain research

authors： Dokas LA,Liauw A

更新日期：1984-07-23 00:00:00

abstract：:Embryonic cortex from 19-day fetuses was transplanted in a medial frontal cortex wound cavity of 105-day-old male rats. Nissl-stained tissue revealed little internal laminar organization. Graft sections impregnated by the Loyez method exhibited bands of myelinated fibers surrounding implants as well as long-interconne...

journal_title：Brain research

authors： Mufson EJ,Labbe R,Stein DG

更新日期：1987-01-13 00:00:00

abstract：:The present experiments showed that there is a cortico-thalamo-cortical projection system in the cat, which originates from the primary visual cortex, relayed by the lateral part of the lateral posterior nucleus of the thalamus, and reaching the medial bank of the lateral suprasylvian visual area. This finding suggest...

journal_title：Brain research

authors： Kato N

更新日期：1990-02-12 00:00:00

abstract：:The retrograde transport of fluorescent substances was used in order to investigate divergent axon collaterals of neurons in the nucleus prepositus hypoglossi (Ph). Fast blue (FB) was injected into the flocculus, paraflocculus and/or the vermis, while nuclear yellow (NY) was injected into the oculomotor nucleus alone ...

journal_title：Brain research

authors： Yingcharoen K,Rinvik E

更新日期：1982-08-19 00:00:00

abstract：:We determined that extracellular potassium ion concentration, [K+]o-induced depolarization, enhances 1-methyl-4-phenylpyridinium ion (MPP+)-induced hydroxyl radical (*OH) generation in the rat striatum. Rats were anesthetized, and sodium salicylate in Ringer's solution (0.5 nmol/microl/min) was infused through a micro...

journal_title：Brain research

authors： Obata T,Aomine M,Yamanaka Y

更新日期：2000-01-10 00:00:00