Abstract:
:Two-day-old rats were pretreated with 50 mg/kg of capsaicin. After 3--4 months, specific binding of [3H]muscimol and [3H]strychnine was measured in membrane preparations from dorsal spinal cord. A 20-30% decrease of the number of [3H]muscimol binding sites was observed after capsaicin treatment. In contrast, [3H]strychnine binding was unchanged. The results provide indirect evidence for a presynaptic location of GABA receptors on capsaicin-sensitive primary afferent neurons.
journal_name
Brain Resjournal_title
Brain researchauthors
Singer E,Placheta Pdoi
10.1016/0006-8993(80)90160-2subject
Has Abstractpub_date
1980-12-08 00:00:00pages
484-7issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(80)90160-2journal_volume
202pub_type
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