Abstract:
:In the urethane-anesthetized rat both electrical stimulation (20 microA, 0.2 ms, 30 s) through micropipettes and glutamate injections (0.1 M, 100 nl) within an area including the dorsal lateral parabrachial nucleus, the adjacent central lateral parabrachial nucleus, the external lateral parabrachial nucleus, the Kölliker-Fuse nucleus, and the adjacent medial parabrachial nucleus led to increases in mean arterial pressure (electrical, 34.2 +/- 18.6 mm Hg; glutamate, 14.0 +/- 8.3 mm Hg). The magnitude of the glutamate responses appeared to be inversely related to the distance between the ventrolateral tip of the brachium conjunctivum and the site of injection. In contrast, electrical stimulation within an area between the caudal medial parabrachial nucleus and the locus coeruleus led to increases in mean arterial pressure (24.4 +/- 12.5 mm Hg), whereas glutamate injections within this area led to decreases in mean arterial pressure (-14.8 +/- 5.3 mm Hg).
journal_name
Brain Resjournal_title
Brain researchauthors
Ward DGdoi
10.1016/0006-8993(88)90570-7subject
Has Abstractpub_date
1988-10-18 00:00:00pages
383-90issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(88)90570-7journal_volume
462pub_type
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