Locus coeruleus neurons in culture have a developmentally transient alpha 1 adrenergic response.

abstract：:In pentobarbitone-anesthetized cats, the spike sequences of dorsal horn neurons were recorded in response to random stimulation of branches of the suralis nerve. Combined frequency- and time-domain analysis was performed on the stimulus and spike trains. Coherence function estimates computed by spectral analysis were ...

journal_title：Brain research

authors： Kuipers U,Laouris Y,Kokkoroyiannis T,Meyer-Lohmann J,Windhorst U

更新日期：1988-10-11 00:00:00

abstract：:GM1 ganglioside injections (i.p.) reduce amphetamine-induced asymmetric rotation in rats 48 h after a partial unilateral transection of the nigrostriatal pathway. We found that this reduction was maximal when rats received their first GM1 injection within 2 h after surgery. Rats injected 4-12 h after surgery, or rats ...

journal_title：Brain research

authors： Li YS,Mahadik SP,Rapport MM,Karpiak SE

更新日期：1986-07-09 00:00:00

abstract：:GEC1 protein shares high identity with GABARAP (GABA(A) Receptor-Associated Protein), interacts with tubulin and GABA(A) receptors and is potentially involved in intracellular transport processes. Recently, using quantitative real time PCR, we have reported the gec1 mRNA expression in different rat brain areas. In the...

journal_title：Brain research

authors： Tolle F,Risold PY,Mansuy-Schlick V,Rossi E,Boyer-Guittaut M,Fraichard A,Jouvenot M

更新日期：2008-05-19 00:00:00

abstract：:Previous studies have demonstrated a higher mean peak frequency of the hippocampal (HPC) theta rhythm during REM sleep in alcohol-nonpreferring (NP) rats when compared with alcohol-preferring (P) rats. Burst firing neurons of the medial septal area (MS/VDB) are thought to pace the HPC theta rhythm during REM sleep and...

journal_title：Brain research

authors： Breen TE,Morzorati SL

更新日期：1996-04-01 00:00:00

abstract：:The vascular changes in the hippocampus and neocortex during kainic acid-induced seizures were investigated in control rats and in rats with chronic, bilateral, cervical sympathectomy. Seizures were induced in unanesthetized, spontaneously breathing rats. The increase in blood flow in the hippocampus of the sympathect...

journal_title：Brain research

authors： Rigaud AS,Pinard E,Borredon J,Seylaz J

更新日期：1990-11-05 00:00:00

abstract：:The opioid peptides Leu-enkephalin, Met-enkephalin and D-Ala2-Met-enkephalinamide were injected at various concentrations into the neocortex and hippocampus of rats to examine their effects on EEG activity and DC potentials. All three compounds were found to elicit spreading depression (SD) in both structures. Higher ...

journal_title：Brain research

authors： Sprick U,Oitzl MS,Ornstein K,Huston JP

更新日期：1981-04-06 00:00:00

abstract：:SBA and NADPH-d histochemistries allow identification of functionally distinct components of the amphibian primary olfactory system. In Pipa, a secondarily aquatic frog, combination of both methodologies, using alternate sets of histological sections, reveals that, apart from Jacobson's organ, this species has a "wate...

journal_title：Brain research

authors： Meyer DL,Fackler IR,Jadhao AG,D'Aniello B,Kicliter E

更新日期：1997-07-11 00:00:00

abstract：:Opioid-binding cell adhesion molecule (OBCAM) is the member of the IgLON family, a subgroup of the immunoglobulin superfamily. In the present study, the functions and dynamics of OBCAM were investigated in hippocampal neurons in vitro. Western blotting revealed that OBCAM expression was low at early stages of culture ...

journal_title：Brain research

authors： Yamada M,Hashimoto T,Hayashi N,Higuchi M,Murakami A,Nakashima T,Maekawa S,Miyata S

更新日期：2007-08-24 00:00:00

abstract：:We have previously reported that some neurons in the anterior hypothalamic area (AHA) are tonically activated by endogenous angiotensins in rats and that activities of these angiotensin II-sensitive neurons in the AHA are enhanced in spontaneously hypertensive rats (SHR). In addition, neural activations induced by bot...

journal_title：Brain research

authors： Kubo T,Hagiwara Y

更新日期：2005-02-08 00:00:00

abstract：:Signaling pathways underlying the cognitive deficit of the Alzheimer's disease (AD) are not completely understood. Protein kinase C (PKC), a major neuronal protein plays a critical role in cellular signal transduction and it is known to be subjected to modulation in AD. We showed previously that, chronic infusion of b...

journal_title：Brain research

authors： Olariu A,Yamada K,Mamiya T,Hefco V,Nabeshima T

更新日期：2002-12-13 00:00:00

abstract：:Normal adult albino and Sprague-Dawley rats, under intraperitoneal Nembutal anesthesia, were used to demonstrate enzymatic activity in the choroid plexus and ventricular ependyma. The brain tissues were perfused or immersed with cold 2% glutaraldehyde and 8% sucrose in 0.1 M cacodylate buffer (pH 7.2-7.4) for 30 min a...

journal_title：Brain research

authors： Masuzawa T,Saito T,Sato F

更新日期：1981-10-19 00:00:00

abstract：:Vestibular nerve branches innervating the sensory epithelia of the three semicircular canals or of the three otolith organs of frogs were selectively labeled in-vitro with biocytin. Labeled afferent fibers from the semicircular canals, utricle, and lagena were encountered in each of the four vestibular nuclei and thei...

journal_title：Brain research

authors： Birinyi A,Straka H,Matesz C,Dieringer N

更新日期：2001-12-07 00:00:00

abstract：:This study examines the role of catecholamines, cell bodies and fibers of passage within the subcoeruleus area (subLC) in the arginine vasopressin (AVP) response to splanchnic osmotic stimulation and hemorrhage. Bilateral chemical lesions were induced into the subLC, approximately 1 mm ventral to the locus coeruleus (...

journal_title：Brain research

authors： King MS,Baertschi AJ

更新日期：1992-05-15 00:00:00

abstract：:The density of binding sites for excitatory amino acids in the hippocampus of SDAT (senile dementia of the Alzheimer type) patients has been investigated. This was compared to that found in younger and old non-dement cases. In the SDAT hippocampi there was a significant decrease in the glutamate and kainate binding. T...

journal_title：Brain research

authors： Represa A,Duyckaerts C,Tremblay E,Hauw JJ,Ben-Ari Y

更新日期：1988-08-09 00:00:00

abstract：:The linear nucleus (Li) is a prominent cell group in the caudal hindbrain, which was first described in a study of cerebellar afferents in the rat by [Watson, C.R.R., Switzer, R.C. III, 1978. Trigeminal projections to cerebellar tactile areas in the rat origin mainly from N. interpolaris and N. principalis. Neurosci. ...

journal_title：Brain research

authors： Fu Y,Tvrdik P,Makki N,Palombi O,Machold R,Paxinos G,Watson C

更新日期：2009-05-19 00:00:00

abstract：:Immunohistochemistry for three calcium-binding proteins calbindin D-28k, calretinin, and parvalbumin revealed neuronal heterogeneity within the GP. Each neurone appeared to express either a single type of calcium binding protein or none at all. The co-localisation of calcium binding proteins was not observed. Combined...

journal_title：Brain research

authors： Cooper AJ,Stanford IM

更新日期：2002-03-08 00:00:00

abstract：:Dopaminergic neurotoxicities of 6-hydroxydopamine (6-OHDA) and the lipopolysaccharide (LPS) were compared in rat mesencephalic cultures plated on poly-L-lysine or on glial monolayers. In the neuron-enriched cultures plated on polylysine, 6-OHDA killed 89% of the tyrosine hydroxylase (TH)-immunopositive neurons, but LP...

journal_title：Brain research

authors： Bronstein DM,Perez-Otano I,Sun V,Mullis Sawin SB,Chan J,Wu GC,Hudson PM,Kong LY,Hong JS,McMillian MK

更新日期：1995-12-15 00:00:00

abstract：:The distribution of immunocytochemically localized subunits that comprise ionotropic non-NMDA excitatory amino acid receptors was examined in human frontal, parietal and temporal association neocortex. AMPA/kainate receptor subunits were identified using a monoclonal antibody (3A11) that recognizes an epitope common t...

journal_title：Brain research

authors： Vickers JC,Huntley GW,Hof PR,Bederson J,DeFelipe J,Morrison JH

更新日期：1995-02-06 00:00:00

abstract：:During a simple reaction time task using auditory or visual stimuli, a total of 96 single units were recorded from the dorsolateral prefrontal cortex of macaque monkeys. These monkeys were trained to depress a lever for a fixed period which produced a tone burst or a small spot of light. After a variable period, the s...

journal_title：Brain research

authors： Ito SI

更新日期：1982-09-09 00:00:00

abstract：:We have developed a novel imaging system "real-time bioradiography", which is able to estimate the dynamic changes of physiological function and metabolism in living tissues using positron emitter-labeled tracers and chemiluminescence probes. The apparatus is comprised of a photon-counting camera, image-controller, cu...

journal_title：Brain research

authors： Sasaki T,Iwamoto A,Tsuboi H,Watanabe Y

更新日期：2006-03-10 00:00:00

abstract：:Bilateral microinjection of kainic acid (30-117 pmol) into the substantia nigra induced convulsive seizures resembling those elicited from limbic system structures. The convulsive seizures, which consisted of facial and forelimb clonus with rearing and falling, developed after a latency of more than 30 min and were pr...

journal_title：Brain research

authors： Maggio R,Liminga U,Gale K

更新日期：1990-10-01 00:00:00

abstract：:In extracellular recordings from chloral hydrate anesthetized rats the 5-HT3 antagonist, BRL 46470A, failed to prevent or reverse the increase in dopamine cell firing rate produced by systemic or iontophoretically applied morphine. A second 5-HT3 antagonist, tropesitron, was similarly found to be ineffective in antago...

journal_title：Brain research

authors： Gifford AN,Wang RY

更新日期：1994-02-28 00:00:00

abstract：:The ventral tegmental area (VTA) is a brain region centrally involved in the development and expression of a variety of behaviors associated with drug use. Orexin/hypocretin (ox/hcrt) and corticotropin releasing factor (CRF) are both peptides released into the VTA, and an increasing number of studies show that both ox...

journal_title：Brain research

authors： Borgland SL,Ungless MA,Bonci A

更新日期：2010-02-16 00:00:00

abstract：:Nerve growth factor (NGF) treatment, given as a single 200 BU intraocular injection at the time of optic nerve transection, was found to significantly accelerate the retinal ganglion cell response to axotomy in the newt (Notophthalmus viridescens). In the control series the per cent of neurons in the retinal ganglion ...

journal_title：Brain research

authors： Turner JE,Delaney RK

更新日期：1979-08-03 00:00:00

abstract：:Oxygen therapy (OT) with hyperbaric oxygen (HBO) or normobaric hyperoxia (NBO) improves the oxygenation of penumbral tissue in experimental ischemic stroke. However, whether this results in the improvement of energy metabolism is unclear. We investigated the effect of both OTs on tissue acidosis and on ATP production....

journal_title：Brain research

authors： Sun L,Strelow H,Mies G,Veltkamp R

更新日期：2011-09-30 00:00:00

abstract：:Somatotopic projections of each maxillary molar tooth were defined by injecting individual teeth with True blue and plotting the location of fluorescent cells in sections of the trigeminal ganglia. Collateral branching was investigated by injecting True blue and Diamidino yellow into pairs of maxillary molar teeth and...

journal_title：Brain research

authors： Atkinson ME,Kenyon C

更新日期：1990-02-05 00:00:00

abstract：:To identify whether altered expressions of voltage gated Ca(2+) channel (VGCC) are linked to inhibitory transmission abnormalities in the gerbil hippocampus, we investigated the effects of GABA receptor or somatostatin receptor (SST) antagonists/agonists on VGCC immunoreactivity in vivo. VGCC immunoreactivities in the...

journal_title：Brain research

authors： Kim DS,Kwak SE,Kim JE,Kim JS,Won MH,Kang TC

更新日期：2006-10-18 00:00:00

abstract：:Opioid modulation of calcium currents was studied in acutely dissociated rat basal forebrain neurons using the whole cell patch-clamp recording technique. The mu-opioid receptor agonist DAGO reversibly suppressed high-voltage activated calcium currents and slowed their rate of activation, while neither delta- nor kapp...

journal_title：Brain research

authors： Soldo BL,Moises HC

更新日期：1997-05-30 00:00:00

abstract：:In recent years, we have carried out several studies on brainstem mechanisms associated with pain modulation. Of particular interest has been the region of the nucleus tractus solitarius (NTS) at the level of the area postrema (AP) in the dorsomedial medulla. This region has been found to be rich in opiate receptors a...

journal_title：Brain research

authors： Bronzino JD,Oley N,Kelly ML,Cordova C,Morgane PJ

更新日期：1983-07-18 00:00:00

abstract：:Extracellular ATP can influence cells via activation of P2X purinoceptors, the distribution of which can be altered in the central and peripheral nervous systems following injury or tissue damage. Here we have investigated the effect of a unilateral section of the cervical vagus nerve on the distribution of P2X(1), P2...

journal_title：Brain research

authors： Atkinson L,Shigetomi E,Kato F,Deuchars J

更新日期：2003-07-04 00:00:00