Development of morphine-induced changes of activity in the mouse.

Abstract:

:The development of spontaneous activity in response to morphine administration was studied at different postnatal ages in C57BL/6 mice. Morphine induced hyperactivity at all ages except in 3-week-old mice, in which a catatonic effect is evident. The results indicate that the neurophysiological and inhibitory systems responsible for the non-analgesic effects of morphine are not characterized by the same developmental pattern.

journal_name

Brain Res

journal_title

Brain research

authors

Filibeck U,Castellano C,Oliverio A

doi

10.1016/0165-3806(81)90029-8

subject

Has Abstract

pub_date

1981-11-01 00:00:00

pages

602-5

issue

4

eissn

0006-8993

issn

1872-6240

journal_volume

254

pub_type

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