An electron microscopic study on enkephalin-like immunoreactive nerve fibers in the celiac ganglion of guinea pigs.

abstract：:The alpha7 nicotinic acetylcholine receptor (nAChR) plays an important role in cognitive processes and has generated recent interest as a potential drug target for treating neurodegenerative disorders such as Alzheimer's disease (AD). The property of Ca(2+) permeation associated with alpha7 nAChR agonism may lead to C...

journal_title：Brain research

authors： Bitner RS,Nikkel AL,Markosyan S,Otte S,Puttfarcken P,Gopalakrishnan M

更新日期：2009-04-10 00:00:00

abstract：:The thalamic midline/intralaminar complex is part of the higher-order thalamus, which receives little sensory input, and instead forms extensive cortico-thalamo-cortical pathways. The midline thalamic nuclei connect with the medial prefrontal cortex and the medial temporal lobe. On the other hand, the intralaminar nuc...

journal_title：Brain research

authors： Silva Ade M,de Santana MA,Morais PL,de Sousa TB,Engelberth RC,Lucena EE,Campêlo CL,Cavalcante JS,Cavalcante JC,Costa MS,do Nascimento ES Jr

更新日期：2014-10-24 00:00:00

abstract：:We investigated the influence of muramyl dipeptide (MDP), a cell wall component of Gram-positive bacteria, on cytokine-induced nitric oxide (NO) production in rat primary astrocytes. MDP alone did not induce NO release in astrocyte cultures. However, MDP increased astrocyte NO production and subsequent nitrite accumul...

journal_title：Brain research

authors： Trajkovic V,Samardzic T,Stosic-Grujicic S,Ramic Z,Mostarica Stojkovic M

更新日期：2000-11-10 00:00:00

abstract：:The effect of electrical stimulation of the prefrontal cortex (PFC) on acetylcholine (ACh) release in the dorsal striatum was investigated using on line in vivo microdialysis. ACh output was sampled before, during and after 20-min periods of 50 and 100 microA stimulation in awake, unrestrained rats. Both currents incr...

journal_title：Brain research

authors： Taber MT,Fibiger HC

更新日期：1994-03-14 00:00:00

abstract：:Our previous studies indicated that L-type calcium channel blocker diltiazem could potentiate pentobarbital-induced hypnosis through serotonergic system. In view of the important role of dorsal raphe nucleus (DRN) on the sleep regulation and the pharmacological actions of calcium channel blocker, we presumed that Ca(2...

journal_title：Brain research

authors： Cui SY,Cui XY,Zhang J,Wang ZJ,Yu B,Sheng ZF,Zhang XQ,Shi XL,Zhang YH

更新日期：2011-07-27 00:00:00

abstract：:A reduction in adenosine deaminase acting on RNA 2 (ADAR2) activity causes the death of spinal motor neurons specifically via the GluA2 Q/R site-RNA editing failure in sporadic amyotrophic lateral sclerosis (ALS). We studied, over time, the spinal cords of ADAR2-knockout mice, which are the mechanistic model mice for ...

journal_title：Brain research

authors： Sasaki S,Takenari Yamashita,Hideyama T,Kwak S

更新日期：2014-03-06 00:00:00

abstract：:Intracellular recordings were obtained from facial motoneurons in anesthetized rats. The effects of iontophoretically applied serotonin were compared to those of the excitatory amino acids glutamate and DL-homocysteic acid (DLH), and the inhibitory amino acids, glycine, GABA and muscimol, under various conditions of m...

journal_title：Brain research

authors： Vandermaelen CP,Aghajanian GK

更新日期：1982-05-06 00:00:00

abstract：:Expression of the protein products of the immediate-early genes (IEGs), members of the fos, jun and krox families (Jun, Fos, and Krox, resp.) was investigated in the spinal cord and sensory ganglia (DRG) of normal rats; and following transection of, block of axonal transport in, or electrical stimulation of their peri...

journal_title：Brain research

authors： Leah JD,Herdegen T,Bravo R

更新日期：1991-12-06 00:00:00

abstract：:Microinjection of the indirect GABAA antagonist, picrotoxin, or the mu opioid agonist, Tyr-D-Ala-Gly-NMe-Phe-Gly-ol (DAGO), into the ventral pallidum and substantia innominata (VP/SI) increases locomotor activity in rats. The VP/SI has direct and indirect projections to the region of the ventral mesencephalon containi...

journal_title：Brain research

authors： Austin MC,Kalivas PW

更新日期：1991-02-22 00:00:00

abstract：:In adult rodents, neuroblasts originating from the subventricular zone migrate tangentially through the rostral migratory stream (RMS) toward the olfactory bulb where they differentiate into interneurons. Neuroblasts in the RMS migrate in chains for a long distance along specifically arranged blood vessels which promo...

journal_title：Brain research

authors： Angelidis A,Račeková E,Arnoul P,Závodská M,Raček A,Martončíková M

更新日期：2018-11-01 00:00:00

abstract：:Traumatic brain injury (TBI) is one of the largest health problems in the United States and affects both cognitive and motor function. Although weakness is common in TBI patients, few studies have demonstrated a reduction in strength in models of brain injury. We have developed a behavioral method to measure volitiona...

journal_title：Brain research

authors： Pruitt D,Hays S,Schmid A,Choua C,Kim L,Trieu J,Kilgard MP,Rennaker RL 2nd

更新日期：2014-09-25 00:00:00

abstract：:The localization of prostaglandin endoperoxide synthase in monkey brain was investigated by the immunoperoxidase method using the monoclonal antibody (PES-7) raised against the enzyme purified from bovine seminal vesicle. The frozen sections with 30-microns thickness were employed after the brain was fixed with perfus...

journal_title：Brain research

authors： Tsubokura S,Watanabe Y,Ehara H,Imamura K,Sugimoto O,Kagamiyama H,Yamamoto S,Hayaishi O

更新日期：1991-03-08 00:00:00

abstract：:Regeneration of descending supraspinal projections were identified in adult goldfish following administration of HRP to different levels of the spinal cord. While in the untreated normal fish 17 nuclei were shown to project into the spinal cord, only 11 of them seem to have participated in the process of regeneration....

journal_title：Brain research

authors： Sharma SC,Jadhao AG,Rao PD

更新日期：1993-08-27 00:00:00

abstract：:The sublaminar binding profiles of (D-Ala-NMe-Phe-Gly-ol)-enkephalin (DAGO), (2-D-penicillamine), 5-D-penicillamine)-enkephalin (DPDPE), and dynorphin A(1-8) (DYN) were studied in the CA1 subfield and dentate gyrus of rat hippocampal formation. Binding was assayed on cryomicrotome sections using coverslip autoradiogra...

journal_title：Brain research

authors： Plager MD,Vogt BA

更新日期：1988-09-13 00:00:00

abstract：:Hippocampal cholinergic neurostimulating peptide (HCNP), originally isolated from soluble fraction of young rat hippocampus and released from hippocampus by the stimulation of N-methyl-d-aspartate (NMDA) receptors, enhances the cholinergic phenotype development in vitro. HCNP precursor protein (HCNP-pp) has multiple f...

journal_title：Brain research

authors： Yamada K,Matsukawa N,Yuasa H,Hattori M,Nakazawa H,Borlongan CV,Ojika K

更新日期：2007-07-16 00:00:00

abstract：:Error processing during motor control involves the evaluation of "high-level" errors (i.e., failures to meet a system goal) by a frontal system involving anterior cingulate cortex and the evaluation of "low-level" errors (i.e., discrepancies between actual and desired motor commands) by a posterior system involving po...

journal_title：Brain research

authors： Krigolson OE,Holroyd CB

更新日期：2007-06-25 00:00:00

abstract：:Serotonin (5-HT) produces both short- and long-term enhancement of generator potentials in identified type B-photoreceptors of Hermissenda. The actions of 5-HT have been shown to modulate both light- and voltage-dependent conductances. To further examine light-dependent processes we studied spontaneous and light-elici...

journal_title：Brain research

authors： Crow T,Pengidore T

更新日期：1993-11-19 00:00:00

abstract：:Brain levels of tyrosine, dopamine (DA), noradrenaline (NA), tryptophan, 5-hydroxytryptamine (5-HT), and 5-hydroxyindoleacetic acid (5-HIAA) were measured after 30, 60 and 120 min of sustained seizure activity, induced in paralyzed, artificially ventilated and anaesthetized (70% N2O) rats by administration of bicucull...

journal_title：Brain research

authors： Calderini G,Carlsson A,Nordström CH

更新日期：1978-11-24 00:00:00

abstract：:The purpose of this study was to identify the functional fields activated in relation to the NO-GO decision. Nine healthy subjects participated in the study which consisted of two test positron emission tomography (PET) scans (GO/NO-GO task and response selection task) and one control scan. In the response selection t...

journal_title：Brain research

authors： Kawashima R,Satoh K,Itoh H,Ono S,Furumoto S,Gotoh R,Koyama M,Yoshioka S,Takahashi T,Takahashi K,Yanagisawa T,Fukuda H

更新日期：1996-07-22 00:00:00

abstract：:An immunohistochemical investigation of the bovine pineal gland was performed using both a rabbit polyclonal antibody and a rat monoclonal antibody against choline acetyltransferase (ChAT). A network of ChAT-immunoreactive (IR) nerve fibers was located throughout the pineal gland, both in the perivascular spaces and b...

journal_title：Brain research

authors： Phansuwan-Pujito P,Mikkelsen JD,Govitrapong P,Møller M

更新日期：1991-04-05 00:00:00

abstract：:The avian pineal exhibits a daily rhythm in the synthesis and secretion of the hormone, melatonin, which is involved in maintaining temporal order within the circadian system of some species. The pineal is richly innervated by sympathetic nerves which originate in the superior cervical ganglia (SCG) and, in the chicke...

journal_title：Brain research

authors： Barrett RK,Underwood H

更新日期：1992-01-13 00:00:00

abstract：:During a recent study of the effects of photoreceptor degeneration on Muller cells, we observed that unlike glia from normal adult retinas, glia from degenerating rat retinas could be cultured and maintained in vitro for several weeks. Using a variety of cell type specific antisera, we show that at least 70% of cells ...

journal_title：Brain research

authors： Sarthy PV

更新日期：1985-06-24 00:00:00

abstract：:Different groups of rats received three injections of either D-amphetamine (2.5 micrograms/0.5 microliters/side) or saline into the ventral tegmental area (VTA), one injection every third day. Two weeks following the last injection, dopamine (DA) neurotransmission in the nucleus accumbens (N. Acc.) was assessed with i...

journal_title：Brain research

authors： Vezina P

更新日期：1993-03-12 00:00:00

abstract：:A disintegrin and metalloproteinase (ADAM) 12 represents a member of a large family of similarly structured multi-domain proteins. In the central nervous system (CNS), ADAM12 has been suggested to play a role in brain development, glioblastoma cell proliferation, and in experimental autoimmune encephalomyelitis. Furth...

journal_title：Brain research

authors： Baertling F,Kokozidou M,Pufe T,Clarner T,Windoffer R,Wruck CJ,Brandenburg LO,Beyer C,Kipp M

更新日期：2010-04-22 00:00:00

abstract：:We observed temporal changes in NACP (precursor protein of non-Abeta component of Alzheimer's disease amyloid), a presynaptic protein a.k. a. alpha-synuclein, in the hippocampus after 5 min ischemia. Intense NACP immunoreactivity was seen transiently around cerebral blood vessels in the CA1 subfield on day 4, and NACP...

journal_title：Brain research

authors： Ishimaru H,Uéda K,Takahashi A,Maruyama Y

更新日期：1998-03-30 00:00:00

abstract：:The present study was designed to examine the trophic effect of sympathetic nerves on cerebrovascular hypertrophy in developmental hypertension. Unilateral superior cervical ganglionectomy was performed in spontaneously hypertensive rats at 4 weeks of age, and wall-to-lumen ratios of cerebral arteries were determined ...

journal_title：Brain research

authors： Sadoshima S,Fujii K,Yao H,Ibayashi S,Fujishima M

更新日期：1986-08-06 00:00:00

abstract：:Inflammatory reactions occurring in the brain after ischemia may contribute to secondary damage. In the present study effects of minocycline, an anti-inflammatory agent, alone or in combination with mild hypothermia, on focal embolic brain ischemia have been examined. Focal ischemic injury was induced by embolizing a ...

journal_title：Brain research

authors： Wang CX,Yang T,Shuaib A

更新日期：2003-02-14 00:00:00

abstract：:Ion channels are integral membrane proteins that allow passive diffusion of ions across membranes. In neurons and in other excitable cells, the harmonious coordination between the numerous types of ion channels shape and propagate electrical signals. Increased accumulation of reactive oxidative species (ROS), and subs...

journal_title：Brain research

authors： Patel R,Sesti F

更新日期：2016-05-15 00:00:00

abstract：:The impact of perinatal exposure to environmental tobacco smoke (ETS) on cognitive development is controversial. We exposed rhesus monkeys to ETS or filtered air (5 animals per group) beginning in utero on day 50 of pregnancy and continuing throughout postnatal testing. In infancy, we evaluated both groups for visual ...

journal_title：Brain research

authors： Golub MS,Slotkin TA,Tarantal AF,Pinkerton KE

更新日期：2007-06-02 00:00:00

abstract：:Neurokinin A and B (NKA and NKB) and neuropeptide K (NPK) were recently isolated from porcine spinal cord and brain, and together with substance P (SP) considerably extend the list of tachykinin-like peptides present in the mammalian nervous system. In order to investigate the distribution of tachykinins in the centra...

journal_title：Brain research

authors： Arai H,Emson PC

更新日期：1986-12-10 00:00:00