Abstract：
:The impact of perinatal exposure to environmental tobacco smoke (ETS) on cognitive development is controversial. We exposed rhesus monkeys to ETS or filtered air (5 animals per group) beginning in utero on day 50 of pregnancy and continuing throughout postnatal testing. In infancy, we evaluated both groups for visual recognition memory and auditory function (auditory brainstem response). The ETS group showed significantly less novelty preference in the visual recognition task whereas no effects on auditory function were detected. These preliminary results support the view that perinatal ETS exposure has adverse effects on cognitive function and indicate further that rhesus monkeys may provide a valuable nonhuman primate model for investigating this link.
journal_name
Brain Resjournal_title
Brain researchauthors
Golub MS,Slotkin TA,Tarantal AF,Pinkerton KEdoi
10.1016/j.brainres.2007.03.001subject
Has Abstractpub_date
2007-06-02 00:00:00pages
102-6eissn
0006-8993issn
1872-6240pii
S0006-8993(07)00509-4journal_volume
1151pub_type
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