Abstract：
:Alpha-bungarotoxin binding sites in chick retina from 12 days in ovo to hatching, were visualized at the ultrastructural level by use of a 1:1 conjugate of horseradish peroxidase with alpha-bungarotoxin. At all stages binding sites in the inner plexiform layer were localized in synapses, predominantly on or near the postsynaptic membrane. Localization of binding sites was found in bipolar and amacrine-cell synapses which appeared morphologically immature as well as in more well developed synapses. The results suggest that alpha-bungarotoxin-binding synapses, tentatively considered to be nicotinic cholinergic, are formed throughout the course of synaptogenesis, and that the aggregation of nicotinic receptors occurs early in the formation of these synapses.
journal_name
Brain Resjournal_title
Brain researchauthors
Daniels MP,Vogel Zdoi
10.1016/0006-8993(80)90774-xsubject
Has Abstractpub_date
1980-11-10 00:00:00pages
45-56issue
1eissn
0006-8993issn
1872-6240pii
0006-8993(80)90774-Xjournal_volume
201pub_type
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