Effects of sex steroids on beta-endorphin release from rat hypothalamus in vitro.

abstract：:The blood-nerve barrier consists of continuous layers of cells linked by tight junctions and includes the endothelial cells which line the endoneurial capillaries and the perineurial cells which surround fascicles of nerve fibers. A facilitated transport carrier protein allows D-glucose to penetrate the barrier. To de...

journal_title：Brain research

authors： Gerhart DZ,Drewes LR

更新日期：1990-01-29 00:00:00

abstract：:Gonadal steroids are thought to act by activation of the genome following cytoplasmic binding, translocation of the hormone--receptor complex to the nucleus and chromatin binding at specific acceptor sites. This study examined the kinetics of chromatin binding of estradiol by hypothalamic and cortical cells of adult g...

journal_title：Brain research

authors： Whalen RE,Olsen KL

更新日期：1978-08-18 00:00:00

abstract：:Entopeduncular nucleus (EPN) cells which project to thalamic and non-thalamic sites were identified by antidromic discharge. Each population of cells, projecting to the ventral anterior nucleus of the thalamus (VA), centrum medianum (CM), the lateral habenula (LHB), and the pedunculopontine nucleus (PP), was distribut...

journal_title：Brain research

authors： Larsen KD,Sutin J

更新日期：1978-11-17 00:00:00

abstract：:The quantitative autoradiographic method with L-(35S)methionine was used to determine the effects of 1-acute (4h) and 2-chronic (14 days) immobilization stress followed by one week of recovery. Acute stress induced a significant decrease in methionine incorporation into proteins in 17 of the 35 brain structures examin...

journal_title：Brain research

authors： Giaume M,Grange E,Baubet V,Gay N,Sermet E,Sarda N,Bobillier P

更新日期：1995-03-27 00:00:00

abstract：:Glutamate is the main excitatory neurotransmitter in the central nervous system. This amino acid mediates learning and memory processes acting through ionotropic and metabotropic receptor binding. Metabotropic glutamate receptors (mGluRs) are G protein-coupled receptors that stimulate phospholipase C (PLC) or inhibit ...

journal_title：Brain research

authors： Iglesias I,Castillo CA,León D,Ruíz MA,Albasanz JL,Martín M

更新日期：2007-06-11 00:00:00

abstract：:In order to investigate the interplay between visuo-spatial attention and central attention, we varied the relative probability (25% vs. 75%) of the responses to lateralized targets in an attentional blink paradigm. When the first target was associated with a less probable response, we observed a larger attentional bl...

journal_title：Brain research

authors： Robitaille N,Jolicoeur P,Dell'Acqua R,Sessa P

更新日期：2007-12-14 00:00:00

abstract：:The transcription factor Phox2b is necessary for the development of the nucleus of the solitary tract (NTS). In this brainstem nucleus, Phox2b is expressed exclusively within a subpopulation of glutamatergic neurons. The present experiments in the adult rat were designed to test whether this subpopulation includes the...

journal_title：Brain research

authors： Geerling JC,Chimenti PC,Loewy AD

更新日期：2008-08-21 00:00:00

abstract：:Electrophysiological studies using rats were performed to examine the influence of locus coeruleus (LC) on nucleus accumbens (Acc) neurons. Spike generation by hippocampal stimulation was inhibited by both LC conditioning stimulation and iontophoretic application of noradrenaline, but spikes elicited by stimulation of...

journal_title：Brain research

authors： Unemoto H,Sasa M,Takaori S

更新日期：1985-07-15 00:00:00

abstract：:The D stereoisomer of dihydroxyphenylalanine (D-DOPA) and its alpha-keto acid metabolite 3,4-dihydroxyphenylpyruvic acid (DHPPA) when infused into the striatum, significantly increased in vivo extracellular dopamine levels. Following D-DOPA administration, the cumulative increase in dopamine levels was 30% of the incr...

journal_title：Brain research

authors： Brannan T,Prikhojan A,Yahr MD

更新日期：1996-04-29 00:00:00

abstract：:L-[35S]Methionine was injected into the dorsal root ganglion (L5) of the adult rat, and migration of the neurofilament polypeptides (the triplet with molecular weights of 200,000, 160,000 and 68,000 daltons), alpha- and beta-tubulins and actin in the sciatic nerve and the dorsal root was quantitatively determined and ...

journal_title：Brain research

authors： Komiya Y,Kurokawa M

更新日期：1980-05-26 00:00:00

abstract：:Experiments were conducted to (1) provide further evidence of the selectivity of [D-Ala2,Leu5,Cys6]enkephalin (DALCE) as an antagonist of delta (delta) receptor ligands and (2) use DALCE as a tool to explore the possible role of delta receptors in restraint stress. Dose- and time-response curves were generated for the...

journal_title：Brain research

authors： Calcagnetti DJ,Bowen WD,Holtzman SG

更新日期：1990-02-19 00:00:00

abstract：:Expression of the immediate-early gene c-fos, a marker of neuronal activation, was employed to localize brainstem neuronal populations functionally related to the expiration reflex (ER). Twelve spontaneously breathing, non-decerebrate, pentobarbital anesthetized cats were used. The level of Fos-like immunoreactivity (...

journal_title：Brain research

authors： Poliacek I,Halasova E,Jakus J,Murin P,Barani H,Stransky A,Bolser DC

更新日期：2007-12-12 00:00:00

abstract：:Recent evidence indicates that the superior colliculus (SC), in addition to its functions in sensory detection, also participates in controlling the generalized activation state of the forebrain, as measured by the electroencephalogram (EEG) or electrocorticogram (ECoG). The mechanisms by which the SC modulates forebr...

journal_title：Brain research

authors： Dringenberg HC,Vanderwolf CH,Noseworthy PA

更新日期：2003-02-21 00:00:00

abstract：:Rat central nervous system (CNS) tissue sections were immunostained by the peroxidase-anti-peroxidase (PAP) method using a rabbit serum directed against rat liver 5'-nucleotidase. In paraffin sections from the brains of 60-day-old rats 5'-nucleotidase immunoreactivity occurred in the same white-matter regions as myeli...

journal_title：Brain research

authors： Cammer W,Sacchi R,Kahn S

更新日期：1985-05-01 00:00:00

abstract：:Hippocampal cholinergic neurons are sensitive to acute ethanol administration, and specific alterations are seen in the functioning of these neurons following chronic ethanol. The present study examined the effects of chronic ethanol exposure and withdrawal on the sensitivity of the hippocampus to local injection of p...

journal_title：Brain research

authors： Gonzalez LP

更新日期：1985-06-03 00:00:00

abstract：:Although it has been reported that dendritic neurotransmitter releases from amacrine cells are regulated by the intracellular Ca(2+) concentration ([Ca(2+)](i)), their spatiotemporal patterns are not well explained. Fast Ca(2+) imagings of amacrine cells in the horizontal slice preparation of goldfish retinas under wh...

journal_title：Brain research

authors： Azuma T,Enoki R,Iwamuro K,Kaneko A,Koizumi A

更新日期：2004-10-08 00:00:00

abstract：:Gamma-hydroxybutyrate (GHB) at low doses (5-10 mg/kg i.p.) increased and at high doses (160-320 mg/kg i.p.) decreased the spontaneous firing rate of prefrontal cortex (PFC) neurons recorded in urethane-anesthetized rats. Only excitations were blocked by NCS-382, a specific GHB receptor antagonist; this suggests that t...

journal_title：Brain research

authors： Godbout R,Jelenic P,Labrie C,Schmitt M,Bourguignon JJ

更新日期：1995-02-27 00:00:00

abstract：:The genomic response following brain ischemia is very complex and involves activation of both protective and detrimental signaling pathways. Immediate early genes (IEGs) represent the first wave of gene expression following ischemia and are induced in extensive regions of the ischemic brain including cerebral cortex a...

journal_title：Brain research

authors： Rickhag M,Teilum M,Wieloch T

更新日期：2007-06-02 00:00:00

abstract：:Intracerebroventricular (i.c.v.) administration of corticotropin-releasing factor (CRF) biphasically affects performance in tests of learning and memory. In the present study, we used CRF, urocortin (Ucn), a recently cloned CRF homologue, and CRF receptor antagonists, to determine which CRF receptor subtype(s) mediate...

journal_title：Brain research

authors： Zorrilla EP,Schulteis G,Ormsby A,Klaassen A,Ling N,McCarthy JR,Koob GF,De Souza EB

更新日期：2002-10-18 00:00:00

abstract：:Neurons containing immunoreactivity to the endogenous lactose-binding lectin, RL-29, were examined in the L4 segment of the spinal cord of rats with an experimental neuropathy. The cells appeared by 5 days and were also present at 14 and 28 days postoperatively. All neurons were found in the dorsal horn ipsilateral to...

journal_title：Brain research

authors： Cameron AA,Dougherty PM,Garrison CJ,Willis WD,Carlton SM

更新日期：1993-08-20 00:00:00

abstract：:The occurrence of unmyelinated axons was examined ultrastructurally in rat molar and incisor root pulps of normal rats, of neonatally capsaicin-treated rats, of rats subjected to neonatal capsaicin treatment followed by resection of the superior cervical ganglion and of sympathectomized but otherwise normal rats. Foll...

journal_title：Brain research

authors： Fried K,Aldskogius H,Hildebrand C

更新日期：1988-10-25 00:00:00

abstract：:The binding of the adenosine receptor agonists, [3H]N-ethylcarboxamidoadenosine (NECA) and [3H]cyclohexyladenosine (CHA) to membrane preparations and to cryostat sections of the rat brain was examined. The xanthine derivative, 1,3-dipropyl-8-cyclopentylxanthine (DPCPX) was ca. 500-fold more effective at A1 than at A2 ...

journal_title：Brain research

authors： Lee KS,Reddington M

更新日期：1986-03-19 00:00:00

abstract：:The immunocytochemical localization of L-glutamate decarboxylase (GAD), the enzyme which which forms gamma-aminobutyric acid (GABA), has been studied in developing rodent cerebellum. During the first 3-4 postnatal days, GAD is distributed along non-terminal portions of axonal processes in close association with small ...

journal_title：Brain research

authors： McLaughlin BJ,Wood JG,Saito K,Roberts E,Wu JY

更新日期：1975-03-07 00:00:00

abstract：:In continuation of earlier computer simulation studies 15 of the feedback inhibition exercised by the Golgi cells of the cerebellum, an attempt is made at modeling the behavior of Purkinje and basket cells under somewhat more complex functional circumstances. The simulation study is based on a realistic network model ...

journal_title：Brain research

authors： Pellionisz A,Szentàgothai J

更新日期：1974-03-15 00:00:00

abstract：:Axonal regeneration over long distances is dependent upon events occurring both in the distal stump and in the neuronal cell body. Little is known concerning how events in the distal stump influence the cell body response to injury, or the axon reaction. In the present study, we examined this relationship for one comp...

journal_title：Brain research

authors： Gold BG,Storm-Dickerson T,Austin DR

更新日期：1993-10-29 00:00:00

abstract：:Simultaneous extracellular recordings from one electrode of 'local' groups of 3-6 neurons were obtained from the auditory cortex of unanesthetized, paralyzed cats. The activity and functional connectivity of local microenvironments were examined under various auditory stimuli. Single cell response patterns were examin...

journal_title：Brain research

authors： Frostig RD,Gottlieb Y,Vaadia E,Abeles M

更新日期：1983-08-08 00:00:00

abstract：:Accumulating evidence suggests that the neuropeptide substance P (SP) and its principal receptor neurokinin 1 (NK1) play a specific role in the behavioral response to opioids and stress that may help to initiate and maintain addictive behavior. In animal models, the NK1 receptor is required for opioids to produce thei...

journal_title：Brain research

authors： Commons KG

更新日期：2010-02-16 00:00:00

abstract：:Systemic administration of kainic acid in the rat results in the development of a characteristic excitotoxic syndrome, consisting of automatisms (wet dog shakes, WDS), sustained limbic seizures and brain damage. Since kainate increases the release of excitatory amino acid neurotransmitters such as glutamate, this synd...

journal_title：Brain research

authors： Baran H,Löscher W,Mevissen M

更新日期：1994-08-01 00:00:00

abstract：:Opioid peptides and their receptors have been localized to the inner ear of the rat and guinea pig mammalian models. The expression of mu opioid receptor (MOR) in the human and mouse cochlea is not yet known. We present MOR protein localization by immunohistochemistry and mRNA expression by in situ hybridization in th...

journal_title：Brain research

authors： Nguyen KD,Mowlds D,Lopez IA,Hosokawa S,Ishiyama A,Ishiyama G

更新日期：2014-11-24 00:00:00

abstract：:Malignant glioma cells maintain an elevated intracellular pH (pH(i)) within hypoxic-ischemic tumor microenvironments through persistent activation of sodium-proton transport (McLean et al., 2000). Amiloride has been reported to selectively kill human malignant glioma cell lines but not primary astrocytes (Hegde et al....

journal_title：Brain research

authors： Harley W,Floyd C,Dunn T,Zhang XD,Chen TY,Hegde M,Palandoken H,Nantz MH,Leon L,Carraway KL 3rd,Lyeth B,Gorin FA

更新日期：2010-12-02 00:00:00