NMDA receptor blockade inhibits glutamate-induced kindling of the rat amygdala.

abstract：:Choline supplementation of the maternal diet has long-term facilitative effects on spatial and temporal memory processes in the offspring. To further delineate the impact of early nutritional status on brain and behavior, we examined effects of prenatal-choline availability on hippocampal oscillatory frequency bands i...

journal_title：Brain research

authors： Cheng RK,Williams CL,Meck WH

更新日期：2008-10-27 00:00:00

abstract：:A search for vasomotor depressor sites in the lateral medullary brainstem of anesthetized cat using microinjections of AMPA has delineated a longitudinal column of sympathoinhibitory neurons consisting of the rostral depressor area, the caudal ventrolateral medulla, and a new intermediate depressor area. Systematic bl...

journal_title：Brain research

authors： Dempesy CW,Richardson DE,Fontana CJ

更新日期：1993-02-19 00:00:00

abstract：:Ethylcholine aziridinium ion (AF64A) diluted in artificial perilymph, or artificial perilymph alone was infused into the cochlea of chinchillas. After a survival time of 7 days, the cochleas were fixed with aldehydes, post-fixed in osmium and embedded in epoxy resin for light and electron microscopy. The ultrastructur...

journal_title：Brain research

authors： Morley BJ,Spangler KM,Schneider BL,Javel E

更新日期：1991-03-22 00:00:00

abstract：:This manuscript describes the use of staining of Fos-related antigens (FRAs) as markers for changes in neuronal activity. The model system consisted of the tuberoinfundibular dopamine (TIDA) neurons located in the arcuate nucleus of the hypothalamus. Under normal conditions, these neurons are devoid of c-Fos staining ...

journal_title：Brain research

authors： Hoffman GE,Le WW,Abbud R,Lee WS,Smith MS

更新日期：1994-08-22 00:00:00

abstract：:It has been accepted that the descending system from the nucleus locus coeruleus (LC)/nucleus subcoeruleus (SC) plays a significant role in spinal nociceptive processing. The present study was designed to examine modulation of nociceptive processing in the caudal part of the trigeminal sensory nuclear complex, the tri...

journal_title：Brain research

authors： Tsuruoka M,Matsutani K,Maeda M,Inoue T

更新日期：2003-12-12 00:00:00

abstract：:Primary afferent neurons in mammalian dorsal root ganglia (DRGs) normally function as independent sensory communication elements. However, it has recently been shown that most DRG neurons are transiently activated when axons of neighboring neurons of the same ganglion are stimulated repetitively and the cross-depolari...

journal_title：Brain research

authors： Xu GY,Zhao ZQ

更新日期：2003-04-25 00:00:00

abstract：:Traumatic brain injury (TBI) causes impairments of both motor and spatial memory performances. Research is only beginning to reveal the biochemical mechanism(s) underlying these deficits. It has been postulated that reactive oxygen species such as the superoxide and hydroxyl radicals, as well as the peroxynitrite anio...

journal_title：Brain research

authors： Long DA,Ghosh K,Moore AN,Dixon CE,Dash PK

更新日期：1996-04-22 00:00:00

abstract：:Pathophysiological responses to peripheral nerve injury include alterations in the activity, intrinsic membrane properties and excitability of spinal neurons. The intrinsic excitability of α-motoneurons is controlled in part by the expression, regulation, and distribution of membrane-bound ion channels. Ion channels, ...

journal_title：Brain research

authors： Romer SH,Dominguez KM,Gelpi MW,Deardorff AS,Tracy RC,Fyffe RE

更新日期：2014-02-14 00:00:00

abstract：:A combined retrograde transport and immunocytochemical study was carried out to determine the projections of the large glycine-immunoreactive neurons in the ventral cochlear nucleus of the guinea pig. Horseradish peroxidase (HRP) was injected into the contralateral cochlear nucleus, and cochlear nucleus sections were ...

journal_title：Brain research

authors： Wenthold RJ

更新日期：1987-07-07 00:00:00

abstract：:Interest in the role of membrane lipids in Schwann cell function prompted this study of lipid antigens on myelin- and non-myelin forming Schwann cells. Using the monoclonal antibodies 07, which recognises galactocerebroside, 08, 09 and 011, the distribution and time course of expression of the 4 membrane lipids have b...

journal_title：Brain research

authors： Eccleston PA,Mirsky R,Jessen KR,Sommer I,Schachner M

更新日期：1987-10-01 00:00:00

abstract：:The content of the mRNAs that code for prepro-corticotropin releasing hormone (ppCRH), prepro-neurotensin/neuromedin N (ppNT/NMN) and prepro-enkephalin (ppENK) was measured using in situ hybridization histochemistry in the various subdivisions of the hypothalamic paraventricular nucleus (PVH) 4 h after a bout of ether...

journal_title：Brain research

authors： Watts AG

更新日期：1991-03-29 00:00:00

abstract：:The nucleus of the solitary tract (NTS) is a critical structure involved in coordinating autonomic and visceral activities. Previous independent studies have demonstrated efferent projections from the NTS to the nucleus paragigantocellularis (PGi) and the central nucleus of the amygdala (CNA) in rat brain. To further ...

journal_title：Brain research

authors： Reyes BA,Van Bockstaele EJ

更新日期：2006-10-30 00:00:00

abstract：:The monoamine levels in the locus coeruleus (LC) were determined by HPLC following specific lesions of the ventral mesencephalic tegmental-A10 regions (VMT-A10) and raphé dorsalis (RD). Only lesions in the VMT-A10 area decreased the dopamine (DA) content, which strongly suggests that the projection from this region to...

journal_title：Brain research

authors： McRae-Degueurce A,Milon H

更新日期：1983-03-21 00:00:00

abstract：:Insulin growth factor 1 (IGF-1) has an important role in brain development and is strongly expressed during recovery after a hypoxic-ischemic injury. Some of its central actions could be mediated through the N-terminal tripeptide fragment of IGF-1: Gly-Pro-Glu (GPE). The neuroprotective properties of GPE given after a...

journal_title：Brain research

authors： Sizonenko SV,Sirimanne ES,Williams CE,Gluckman PD

更新日期：2001-12-13 00:00:00

abstract：:Growth hormone releasing factor (GRF) applied by iontophoresis, pressure, and in the perfusate, increased (14.81%) or decreased (45.92%) the firing of paraventricular neurons extracellularly recorded from guinea-pig hypothalamic slices. Effects were similar whatever the mode of application and were elicited in the nan...

journal_title：Brain research

authors： Poulain P,Carette B

更新日期：1986-04-23 00:00:00

abstract：:Occipital cortex of 19-day-old fetal rats was dissociated and cultured in vitro for 2-5 weeks in horse serum supplemented Eagle's MEM. The outgrowing neurons rapidly formed a dense network which started to degenerate after 3 weeks in vitro. By means of electron microscopy the numerical development of 6 different categ...

journal_title：Brain research

authors： Romijn HJ,Mud MT,Habets AM,Wolters PS

更新日期：1981-07-01 00:00:00

abstract：:The suprachiasmatic nucleus (SCN) and the pineal body in 3 types of inherited hormone-deficient mice, the dw, lit and hyt mice were examined by morphological, morphometric and biochemical techniques. In the dw and lit mice the SCN was underdeveloped. In the ventral part of the SCN, where most of the retinal fibers app...

journal_title：Brain research

authors： Noguchi T,Sugisaki T,Kudo M,Satoh I

更新日期：1986-05-01 00:00:00

abstract：:The cholinergic presynaptic terminals of Torpedo electric organ have been examined morphometrically following stimulation by KCI and sucrose. The objective was to confirm correlations predicted by the vesicle hypothesis between miniature end-plate potentials (MEPPs) and morphometric changes in terminal ultrastructure....

journal_title：Brain research

authors： Fox GQ,Kriebel ME

更新日期：1997-04-25 00:00:00

abstract：:Effects of systemic administration of a single dose (50 mg/kg) of ethosuximide (ESM) on extracellularly recorded thalamic (nucleus centralis lateralis, CL; nucleus reticularis, RE) and cortical neurons and on cortical EEG activity of acute cats, have been studied. In intact animals ESM led to: (a) desynchronization of...

journal_title：Brain research

authors： Pellegrini A,Dossi RC,Dal Pos F,Ermani M,Zanotto L,Testa G

更新日期：1989-09-18 00:00:00

abstract：:The intermediate, medial part of the hyperstriatum ventrale (IMHV) is an area of the avian forebrain which is essential for two forms of early learning in the domestic chick. We have developed an in vitro slice preparation which contains part of the IMHV and have found that the electrophysiological properties of the a...

journal_title：Brain research

authors： Bradley PM,Burns BD,King TM,Webb AC

更新日期：1996-07-15 00:00:00

abstract：:The distribution of AMPA-type glutamate receptor (GluR) subunits was studied in the Edinger-Westphal nucleus (EW) of chicks and pigeons. GluR1, GluR2, GluR3 and GluR4 subunits appeared to be present in EW neurons of both species, but interspecific differences were observed in the abundance of the different types of su...

journal_title：Brain research

authors： Toledo CA,Britto LR,Pires RS,Veenman CL,Reiner A

更新日期：2002-08-23 00:00:00

abstract：:Myelin, the lipid-rich sheath that insulates axons to facilitate rapid conduction of action potentials, is an evolutionary innovation of the jawed-vertebrate lineage. Research efforts aimed at understanding the molecular mechanisms governing myelination have primarily focused on rodent models; however, with the advent...

journal_title：Brain research

authors： Ackerman SD,Monk KR

更新日期：2016-06-15 00:00:00

abstract：:Slices of rat hippocampus were exposed to 700 MHz continuous wave radiofrequency (RF) fields (25.2-71.0 V m(-1), 5-15 min exposure) in a stripline waveguide. At low field intensities, the predominant effect on the electrically evoked field potential in CA1 was a potentiation of the amplitude of the population spike by...

journal_title：Brain research

authors： Tattersall JE,Scott IR,Wood SJ,Nettell JJ,Bevir MK,Wang Z,Somasiri NP,Chen X

更新日期：2001-06-15 00:00:00

abstract：:Alterations in neurotrophic signaling pathways may contribute to the changes in the mesolimbic dopamine system induced by chronic morphine exposure. In a rat model of morphine dependence, we previously identified increased levels of phospholipase C gamma-1 (PLCgamma1) immunoreactivity specifically within the ventral t...

journal_title：Brain research

authors： Wolf DH,Nestler EJ,Russell DS

更新日期：2007-07-02 00:00:00

abstract：:Kindling of the amygdaloid complex in rats results in an enhanced emotionality frequently expressed by an elevated anxiety and defensive attitude toward other animals. Defensive attitude may have important consequences in social context and if tested in a large space it may eventually lead to social withdrawal. To tes...

journal_title：Brain research

authors： Haimovici A,Wang Y,Cohen E,Mintz M

更新日期：2001-12-13 00:00:00

abstract：:This review provides a snapshot of the current ethical issues related to research with human brain organoids. The issues fall into the following main themes: research oversight; human biomaterials procurement and donor consent; translational delivery; animal research; and organoid consciousness and moral status. Each ...

journal_title：Brain research

authors： Hyun I,Scharf-Deering JC,Lunshof JE

更新日期：2020-04-01 00:00:00

abstract：:The results showed that the development of seizures (pentylenetetrazole, PTZ-induced kindling; PTZ was administered to rats at a subconvulsive dose of 35mg/kg three times a week, i.p.) was accompanied by a progressive recruitment of limbic structures and a characteristic pattern of changes in the brain tissue concentr...

journal_title：Brain research

authors： Maciejak P,Szyndler J,Turzyńska D,Sobolewska A,Bidziński A,Kołosowska K,Płaźnik A

更新日期：2010-06-25 00:00:00

abstract：:Rats received a unilateral lesion of the nucleus basalis magnocellularis (NBM) by infusion of ibotenic acid. Starting 2 weeks after the lesion, the animals were treated with nerve growth factor (NGF) or brain-derived neurotrophic factor (BDNF) by intraparenchymal infusion of 3 micrograms per day for 4 weeks. Lesioned ...

journal_title：Brain research

authors： Dekker AJ,Fagan AM,Gage FH,Thal LJ

更新日期：1994-03-07 00:00:00

abstract：:Retrograde transport of horseradish peroxidase (HRP) was used to identify supraependymal neurons projecting to the pituitary gland in the hamster. Supraependymal neurons overlying the median eminence were labeled by HRP injections into the neural and intermediate lobes of the pituitary gland; no neurons were labeled f...

journal_title：Brain research

authors： Michael DB,Hazlett JC,Mitchell JA

更新日期：1989-01-30 00:00:00

abstract：:Field potentials and radial current source-densities (CSDs) evoked by optic tract stimulation were observed in goldfish tectum in vitro. The effects of different concentrations of calcium and magnesium were studied to improve understanding of component events in retinotectal transmission and interpretations of effects...

journal_title：Brain research

authors： Langdon RB,Manis PB,Freeman JA

更新日期：1988-02-16 00:00:00