Abstract：
:The intermediate, medial part of the hyperstriatum ventrale (IMHV) is an area of the avian forebrain which is essential for two forms of early learning in the domestic chick. We have developed an in vitro slice preparation which contains part of the IMHV and have found that the electrophysiological properties of the area show a considerable degree of plasticity. In particular, age and prior learning appear to modify the properties of single neurons recorded intracellularly. We have used the in vitro slice preparation to make intracellular recordings from 38 single neurons in the IMHV and have then dye-injected each cell to find out whether there is any relationship between electrophysiological and morphological characteristics. The basic membrane properties of each neuron were measured. Responses to standard electrical stimuli, delivered extracellularly, were also recorded, and each neuron was classified on this basis. Finally, the presence or absence of spontaneously occurring bursts of EPSPs was noted. At the end of recording biocytin was injected into the cell. After the tissue had been processed, each cell was drawn. The area of the cell body was measured, the number of dendrites was counted, and dendritic extent and branching were estimated. Each cell was also classified as 'spiny' or 'non-spiny'. We found that neurons displaying one particular type of response to external stimulation possessed a well defined set of morphological and electrical properties. In addition, three parameters--electrical resistance, somatic area, and the presence or absence of dendritic spines--were related to specific subsets of anatomical and physiological characteristics. The possible relevance of these findings to the plasticity of the IMHV is discussed.
journal_name
Brain Resjournal_title
Brain researchauthors
Bradley PM,Burns BD,King TM,Webb ACdoi
10.1016/0006-8993(96)00361-7subject
Has Abstractpub_date
1996-07-15 00:00:00pages
125-32issue
1-2eissn
0006-8993issn
1872-6240pii
0006-8993(96)00361-7journal_volume
727pub_type
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