Ether anesthesia differentially affects the content of prepro-corticotropin-releasing hormone, prepro-neurotensin/neuromedin N and prepro-enkephalin mRNAs in the hypothalamic paraventricular nucleus of the rat.

Abstract:

:The content of the mRNAs that code for prepro-corticotropin releasing hormone (ppCRH), prepro-neurotensin/neuromedin N (ppNT/NMN) and prepro-enkephalin (ppENK) was measured using in situ hybridization histochemistry in the various subdivisions of the hypothalamic paraventricular nucleus (PVH) 4 h after a bout of ether anesthesia. This treatment increased the content of ppENK mRNA only in a selected region of the dorsal medial parvicellular PVH (PVHmpd). PpNT/NMN mRNA was undetectable in the PVH of control animals, but hybridization was observed in the PVHmpd of anesthetized animals. The content of ppCRH mRNA was unchanged 4 h after ether aesthesia.

journal_name

Brain Res

journal_title

Brain research

authors

Watts AG

doi

10.1016/0006-8993(91)90080-f

subject

Has Abstract

pub_date

1991-03-29 00:00:00

pages

353-7

issue

2

eissn

0006-8993

issn

1872-6240

pii

0006-8993(91)90080-F

journal_volume

544

pub_type

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