L-[3H]Glutamate binds to kainate-, NMDA- and AMPA-sensitive binding sites: an autoradiographic analysis.

abstract：:Immunohistochemistry was used to examine the co-occurrence of nicotinic acetylcholine receptor subunits with calcium-binding proteins in ganglion cells of the chick retina. The alpha3 subunit was rarely observed in ganglion cells containing calbindin, calretinin, or parvalbumin. On the other hand, the alpha8 subunit w...

journal_title：Brain research

authors： Araki CM,Pires RS,Britto LR,Lindstrom JM,Karten HJ,Hamassaki-Britto DE

更新日期：1997-11-07 00:00:00

abstract：:Several neurologic illnesses in which excitotoxic mechanisms may play a role increase in prevalence with age. In the present study we examined the susceptibility of rats to quinolinic acid striatal lesions at 1, 4 and 20 months of age, and susceptibility to N-methyl-D-aspartate (NMDA) at 1 and 4 months of age. The ext...

journal_title：Brain research

authors： Finn SF,Hyman BT,Storey E,Miller JM,Beal MF

更新日期：1991-10-25 00:00:00

abstract：:The pleiotropic cytokine tumor necrosis factor-alpha (TNFalpha) is implicated in the development of persistent pain through its actions in the periphery and in the central nervous system (CNS). Activation of the alpha(2)-adrenergic receptor is associated with modulation of pain, possibly through its autoregulatory eff...

journal_title：Brain research

authors： Covey WC,Ignatowski TA,Knight PR,Spengler RN

更新日期：2000-03-17 00:00:00

abstract：:Individuals are found to have better recall for self-referent information than other types of information. However, attribution research has shown that self-reference is highly correlated with emotional valence. The present study attempted to identify and separate the processing of self-reference and emotional valence...

journal_title：Brain research

authors： Watson LA,Dritschel B,Obonsawin MC,Jentzsch I

更新日期：2007-06-04 00:00:00

abstract：:The structure of the plasma membrane of two neuronal cell types was quantitatively assessed in freeze-fracture replicas of rat cerebellar cortex from 2 to 73 postnatal days. The measurement of the number and size of intramembrane particles (IMP) in different regions of the Purkinje cells and of the granule cell showed...

journal_title：Brain research

authors： Garcia-Segura LM,Perrelet A

更新日期：1981-03-09 00:00:00

abstract：:When one eye of a rat is removed at birth an increased projection to the brain is found from the remaining eye. This projection arises from the whole retina and mainly from ganglion cells which project to only one hemisphere of the brain. In the normal course of development many of these cells die and the uncrossed pr...

journal_title：Brain research

authors： Jeffery G,Perry VH

更新日期：1981-08-01 00:00:00

abstract：:Spreading depression (SD) is characterized by a transient breakdown of neuronal function concomitant with a massive failure of ion homeostasis. It is a phenomenon that can be induced in neocortical tissue by raising excitability, e.g. injection of K(+), application of glutamatergic agonists, or blocking Na(+)/K(+) ATP...

journal_title：Brain research

authors： Köhling R,Koch UR,Hagemann G,Redecker C,Straub H,Speckmann EJ

更新日期：2003-06-13 00:00:00

abstract：:The development of glial precursor cells in the mammalian optic nerve depends on retinal ganglion cell (RGC) axons, but the signals that mediate this neuron-to-glia interaction have not been fully characterized. Sonic hedgehog (Shh) is expressed by RGCs, and we showed previously that it is required for the specificati...

journal_title：Brain research

authors： Dakubo GD,Beug ST,Mazerolle CJ,Thurig S,Wang Y,Wallace VA

更新日期：2008-09-04 00:00:00

abstract：:Hindpaw injections of carrageenan (CARRA) decreased paw withdrawal latencies to radiant heat and increased hindpaw edema. At the peak of hyperalgesia, the content of immunoreactive guanosine 3',5'-cyclic monophosphate (i-cGMP) was increased, while immunoreactive adenosine 3',5'-cyclic monophosphate (i-cAMP) was decrea...

journal_title：Brain research

authors： Garry MG,Richardson JD,Hargreaves KM

更新日期：1994-05-16 00:00:00

abstract：:Pharmacological studies have documented that altered drug responses, particularly to benzodiazepines, are common in elderly populations. While numerous factors may contribute to changes in drug response, age-related alterations in the molecular composition of GABA(A) receptors may be a key factor in regulating these r...

journal_title：Brain research

authors： Rissman RA,Nocera R,Fuller LM,Kordower JH,Armstrong DM

更新日期：2006-02-16 00:00:00

abstract：:Selective lesions of the noradrenergic systems of the paraventricular nucleus (PVN) of the hypothalamus with 6-hydroxydopamine (6-OHDA) lengthen the periodicity of the migrating myoelectric complex (MMC), an index of intestinal motility, in rats. These lengthening effects resemble those obtained after lesions of the l...

journal_title：Brain research

authors： Bonaz B,Martin L,Beurriand E,Hostein J,Feuerstein C

更新日期：1992-06-26 00:00:00

abstract：:The horizontal and vertical vestibulo ocular reflex (VOR) of head tilted (het) mutant mice was compared to C57BL/6 controls. Eye movements were recorded in darkness using a temporarily attached search coil. Contributions of semicircular canal versus otolith organ signals were investigated by providing a canal only (ve...

journal_title：Brain research

authors： Harrod CG,Baker JF

更新日期：2003-05-16 00:00:00

abstract：:The hippocampus plays an important role in learning and memory and possibly contributes to the formation of pain-related memory and emotional responses. However, there is currently little data linking the hippocampus to neuropathic pain. It has been reported that NF-κB is an important regulatory factor in memory conso...

journal_title：Brain research

authors： Chou CW,Wong GT,Lim G,McCabe MF,Wang S,Irwin MG,Mao J

更新日期：2011-03-10 00:00:00

abstract：:Nerve growth factor (NGF) transported intraaxonally from the adrenergic nerve terminals in the iris to the cell bodies in the superior cervical ganglion resulted in an increase in the activity of the enzyme ornithine decarboxylase in the ganglion. This occurred in both six-day-old and adult rats with the relative effe...

journal_title：Brain research

authors： Hendry IA,Bonyhady R

更新日期：1980-10-27 00:00:00

abstract：:A number of studies describe strain-related differences in the motor behavior of rats. Inbred albino F344 rats are found to be impaired in procedural spatial learning, skilled reaching, and over ground locomotion in relation to pigmented out bred Long Evans (LE) rats. These deficits could be related to the functional ...

journal_title：Brain research

authors： Wawryko P,Ward NL,Whishaw IQ,Ivanco TL

更新日期：2004-12-10 00:00:00

abstract：:In the laboratory rat, inhalation (30 s) of high (> 70%) CO2 concentrations resulted in short-term (1-3 min) anesthesia, followed by a prolonged (up to 60 min) mild antinociception. Exposure to 100% CO2 resulted in significant thermal (hot-plate, 52 degrees, and tail-flick) and mechanical (tail-pinch, 886 g force) ant...

journal_title：Brain research

authors： Mischler SA,Alexander M,Battles AH,Raucci JA Jr,Nalwalk JW,Hough LB

更新日期：1994-03-21 00:00:00

abstract：:The retinoblastoma protein (pRb) is a key regulator of cell growth, differentiation and survival. pRb(-/-) mice show abnormal neuronal cell death in the developing brain. The function of pRb is regulated by its phosphorylation state. In this study, the phosphorylation of pRb during retinoic acid (RA)-induced neuronal ...

journal_title：Brain research

authors： Watanabe Y,Watanabe T,Kitagawa M,Taya Y,Nakayama K,Motoyama N

更新日期：1999-09-25 00:00:00

abstract：:The basic characteristics of the electroencephalograms (EEGs) of the entorhinal cortex (EC) were compared to those of the olfactory bulb (OB) and prepiriform cortex (PPC) in the awake cat, using methods that take into account linear (coherence functions) and non-linear relationships (mutual information). The frequency...

journal_title：Brain research

authors： Boeijinga PH,Lopes da Silva FH

更新日期：1988-05-17 00:00:00

abstract：:Diffusion patterns of 14C-labeled penicillin, resulting from microinjections into different neocortical laminae, were compared with simultaneous electrophysiologic monitoring of epileptogenesis across these laminae. Injections into layer IV produced response alterations quickly in all recorded layers even with penicil...

journal_title：Brain research

authors： Chatt AB,Ebersole JS

更新日期：1984-01-09 00:00:00

abstract：:Adaptive behaviour requires that organisms continuously monitor the environment for potentially significant information and evaluate whether currently unattended stimuli afford a behavioural change. Here we used event-related functional magnetic resonance imaging in humans to assess the neural mechanisms underlying th...

journal_title：Brain research

authors： Gruber O,Diekhof EK,Kirchenbauer L,Goschke T

更新日期：2010-09-10 00:00:00

abstract：:The present study was designed to assess the effect of protein kinase C (PKC) and cAMP-dependent protein kinase (PKA) on desensitization of Torpedo acetylcholine (ACh) receptors by analyzing summated macroscopic currents in an outside-out patch-clamp configuration. Normal ACh receptors desensitized with a fast (6 ms) ...

journal_title：Brain research

authors： Nishizaki T,Sumikawa K

更新日期：1998-11-23 00:00:00

abstract：:To examine the effect of development on rabbit brain insulin and insulin-like growth factor (IGF) receptor expression, we characterized and quantitated receptor mRNAs by Northern blot analysis and affinity-labeled ligand bound receptors by SDS-PAGE and autoradiography. At various stages of development ranging from 23 ...

journal_title：Brain research

authors： Devaskar SU,Sadiq HF,Holtzclaw L,George M

更新日期：1993-03-05 00:00:00

abstract：:Variation in cell loss and mossy fiber reorganization was examined along the longitudinal axis of the dentate gyrus from temporal lobe epileptic (TLE) patients. Previous evidence has indicated that the anterior hippocampus is prone to seizure activity. We compared granule and hilar cell number in addition to Timm stai...

journal_title：Brain research

authors： Masukawa LM,O'Connor WM,Lynott J,Burdette LJ,Uruno K,McGonigle P,O'Connor MJ

更新日期：1995-04-24 00:00:00

abstract：:We evaluated the effects of glycine exposure upon CA1-evoked response in the rat hippocampal slice. Exposure to 10 mM glycine for 16 min produced rapid neuronal firing and increased orthodromic population spike (PS), followed by loss of CA1 neural transmission. Upon recovery, CA1 orthodromic and antidromic PS regained...

journal_title：Brain research

authors： Wallis RA,Panizzon KL,Nolan JP

更新日期：1994-11-21 00:00:00

abstract：:Dopaminergic and glutamatergic afferents simultaneously innervate median spiny neurons (MSNs) and interact to mediate basal ganglia functions. However, the association between dopaminergic and glutamatergic axons is not clear. In the present study, nigrostriatal, corticostriatal, and thalamostriatal axons were anterog...

journal_title：Brain research

authors： Xu C,Zhao J,Liu Y,Zeng X,Jia Y,Wang Y,Jiang X,Xu Q

更新日期：2012-11-27 00:00:00

abstract：:Several studies have demonstrated in the past that endogenous opioid peptides and opioid receptors may be involved as mediators of brain tissue growth and function in the neonate. Applying histological and autoradiographic methods, we have examined the effect of the mu-receptor-specific antagonist, naltrexone, on the ...

journal_title：Brain research

authors： Schmahl W,Funk R,Miaskowski U,Plendl J

更新日期：1989-05-08 00:00:00

abstract：:Our previous study [32] indicated that blockade of kappa-opioid receptors with nor-binaltorphimine (nor-BNI) in the medial preoptic area (MPOA) produced two different LH responses during midpregnancy in the rat: an increase in basal pulsatile LH secretion, followed in many cases by a larger and/or sustained increase i...

journal_title：Brain research

authors： Zhen S,Gallo RV

更新日期：1995-11-06 00:00:00

abstract：:In vitro uptake of labeled serotonin (5-HT) has allowed the radioautographic detection of serotoninergic fibers in the cat spinal cord at thoracic and lumbar levels. The specificity of labeling was ensured by the conditions of incubation ([3H]5-HT was 10(-7) M) and by test control experiments with concomitant 10(-6) M...

journal_title：Brain research

authors： Segu L,Calas A

更新日期：1978-09-29 00:00:00

abstract：:Following the injection of small volumes of horseradish peroxidase conjugated with wheatgerm agglutinin into the substantia nigra of the rat, a high proportion of the total neuronal population in parts of the ipsilateral neostriatum was retrogradely labelled with horseradish peroxidase. Quantitative estimates in 1-mic...

journal_title：Brain research

authors： Bolam JP,Powell JF,Totterdell S,Smith AD

更新日期：1981-09-14 00:00:00

abstract：:The expressions of mRNAs encoding G protein alpha subunits were analyzed in the cerebral cortex of amygdaloid kindled rats. A remarkable increase in Gsalpha mRNA were observed on the bilateral cerebral cortex at 24 h after the last generalized seizure and persisted 3 weeks on the unstimulated side. Gi2alpha mRNA level...

journal_title：Brain research

authors： Iwasa H,Kikuchi S,Miyagishima H,Mine S,Koseki K,Hasegawa S

更新日期：1999-02-13 00:00:00