Carrageenan-induced inflammation alters the content of i-cGMP and i-cAMP in the dorsal horn of the spinal cord.

abstract：:A reduction in adenosine deaminase acting on RNA 2 (ADAR2) activity causes the death of spinal motor neurons specifically via the GluA2 Q/R site-RNA editing failure in sporadic amyotrophic lateral sclerosis (ALS). We studied, over time, the spinal cords of ADAR2-knockout mice, which are the mechanistic model mice for ...

journal_title：Brain research

authors： Sasaki S,Takenari Yamashita,Hideyama T,Kwak S

更新日期：2014-03-06 00:00:00

abstract：:The extraction and utilization of sound level changes in acoustic-autonomic reflex systems were studied on a vasoconstriction response in the tail of nonanesthetized rats. The vasoconstriction was found to depend on sound level and changes of level in the following ways. (a) It increased as a linear function of sound ...

journal_title：Brain research

authors： Borg E

更新日期：1980-04-21 00:00:00

abstract：:On average, cells in areas 17, 18 or 19 of normal and stroboscopically reared cats respond with equal maximum firing rates to a narrow bar of light whether moving at the optimal velocity in the preferred direction of movement of flashed at the optimal position within the receptive field. Firing rates in the non-prefer...

journal_title：Brain research

authors： Duysens J,Orban GA

更新日期：1981-09-07 00:00:00

abstract：:Attachment, growth and morphological differentiation of isolated adult rat oligodendrocytes cultured on a naturally produced basement membrane-like extracellular matrix (ECM) occurred much faster than on poly-L-lysine (PLL) coated tissue culture dishes. In each individual trial the cells cultured on ECM exhibited, wit...

journal_title：Brain research

authors： Lubetzki-Korn I,Ovadia H,Vlodavsky I,Fuks Z,Abramsky O

更新日期：1983-05-09 00:00:00

abstract：:The present experiments were aimed to determine the extent to which differentiated neuroblastoma cells may serve as a donor source for neural transplantation studies. Rodent-derived C1300 and human-derived LA-N-2 cells stained positively for choline acetyltransferase in vitro whether left untreated or rendered amitoti...

journal_title：Brain research

authors： Kordower JH,Notter MF,Gash DM

更新日期：1987-08-04 00:00:00

abstract：:Painful experience is a complex entity made up of sensory, affective, motivational and cognitive dimensions. The neural mechanisms involved in pain perception acts in a serial and a parallel way, discriminating and locating the original stimulus and also integrating the affective feeling, involved in a special situati...

journal_title：Brain research

authors： Almeida TF,Roizenblatt S,Tufik S

更新日期：2004-03-12 00:00:00

abstract：:It has been proposed that disruption of cholinergic input to the hippocampus and cortex contributes to the learning and memory deficits associated with aging. The data reviewed here, however, suggest that the oft-stated generalization that normal aging is characterized by disruption of cholinergic input to the hippoca...

journal_title：Brain research

authors： Decker MW

更新日期：1987-11-01 00:00:00

abstract：:Extracellular recordings were conducted in the paraflocculus of anesthetized Long-Evans pigmented rats to determine how ionotophoresis of norepinephrine (NE) affects the responsiveness of individual Purkinje cells and interneurons to presentations of visual stimuli within their visual receptive fields. Presentations o...

journal_title：Brain research

authors： Moises HC,Burne RA,Woodward DJ

更新日期：1990-04-30 00:00:00

abstract：:Smoking is considered the leading cause of preventable death in the United States, but studies in animals suggest that nicotine is only weakly reinforcing. The maintenance of a dangerous habit by a weakly reinforcing agent has been the topic of some dispute. Using a two-lever "choice" self-administration procedure dev...

journal_title：Brain research

authors： Manzardo AM,Stein L,Belluzzi JD

更新日期：2002-01-04 00:00:00

abstract：:Astrocytes associated with beta-amyloid (Aβ)-deposited senile plaques are a common neuropathological feature of Alzheimer's disease (AD). There is little doubt that the association of Aβ with the major component in the central nervous system cells significantly influences disease progression, however, the molecular me...

journal_title：Brain research

authors： Satoh K,Akatsu H,Yamamoto T,Kosaka K,Yokota H,Yamada T

更新日期：2012-03-02 00:00:00

abstract：:The dtsz mutant hamster represents a model of primary paroxysmal dystonia, in which dystonic episodes occur in response to stress. Previous examinations demonstrated striatal dysfunctions in dtsz hamsters. In the present study, in situ hybridization was used to examine preproenkephalin and prodynorphin expression as p...

journal_title：Brain research

authors： Nobrega JN,Parkes JH,Wong P,Raymond R,Richter A

更新日期：2004-07-23 00:00:00

abstract：:Seizure is a common acute and severe disease in infants and children. Recurrent seizures or persistent seizures may cause irreversible brain damage. Mitogen activated protein kinase (MAPK) signaling pathway is associated with an inflammatory response, however it's involvement in the pathological process of seizures is...

journal_title：Brain research

authors： Hu QP,Huang XY,Peng F,Yang H,Wu C

更新日期：2020-10-15 00:00:00

abstract：:The distribution of neurocalcin-immunoreactive (NC-ir) primary sensory neurons was examined in the trigeminal ganglion (TG), mesencephalic trigeminal tract nucleus (Mes5) and intraoral structures. NC-ir primary sensory neurons were located in the TG but not the Mes5. The coexpression study demonstrated that virtually ...

journal_title：Brain research

authors： Ichikawa H,Hidaka H,Sugimoto T

更新日期：2000-05-02 00:00:00

abstract：:The fine structure of reaggregating cultures of cells from 6- to 7-day-old mouse cerebellum was studied at intervals between 3 and 21 days in vitro (DIV). The resulting aggregates consisted mainly of small neurons (granule, stellate and basket cells), neuroglial cells and their processes. Large neurons were rarely pre...

journal_title：Brain research

authors： Orkand PM,Lindner J,Schachner M

更新日期：1984-09-01 00:00:00

abstract：:Using fMRI, cerebral activations were studied in 24 classically-trained keyboard performers and 12 musically unskilled control subjects. Two groups of musicians were recruited: improvising (n=12) and score-dependent (non-improvising) musicians (n=12). While listening to both familiar and unfamiliar music, subjects eit...

journal_title：Brain research

authors： Harris R,de Jong BM

更新日期：2015-10-22 00:00:00

abstract：:Experiments were carried out in rats to (1) elaborate upon the sepcificity of drug action in the periaqueductal gray matter (PAG), and (2) to evaluate the posible congruence of PAG sites of morphine-induced and stimulation-produced analgesis (SPA) applied at virtually identical PAG loci. It was demonstrated that the e...

journal_title：Brain research

authors： Lewis VA,Gebhart GF

更新日期：1977-03-25 00:00:00

abstract：:The properties of 5 beta-reductase, 5 alpha-reductase and aromatase, 3 testosterone metabolizing enzymes, were studied in the quail brain by an in vitro incubation technique. The results describe the changes in time of metabolite production and the effects of temperature, enzyme and cofactor concentrations. The appare...

journal_title：Brain research

authors： Schumacher M,Contenti E,Balthazart J

更新日期：1984-07-02 00:00:00

abstract：:The ability of beta-phenylethylamine (PEA) to reverse (1) chlorpromazine-induced activation of striatal tyrosine hydroxylase, and (2) catalepsy produced by chlorpromazine, was examined. PEA, in a dose of 75 mg/kg, caused approximately 50% reduction in the degree of tyrosine hydroxylase stimulation produced by 20 mg/kg...

journal_title：Brain research

authors： Stoff DM,Gale K

更新日期：1981-05-04 00:00:00

abstract：:The stimulated (40 Hz) release of enkephalin from the myenteric plexus can be modulated by multiple types of opiate receptor. The direction of the modulation is not fixed but is bimodal. Both an inhibition and an enhancement of evoked release is observed depending on the concentration of opioid agonist that is used. E...

journal_title：Brain research

authors： Xu H,Smolens I,Gintzler AR

更新日期：1989-12-11 00:00:00

abstract：:In the course of studies on the responsiveness of mediobasal hypothalamic neurons to the iontophoretic application of cortisol, it was found that positive currents applied to a sodium chloride (1 M) barrel alone, but not to a choline chloride (1 M) barrel, frequently increased the firing of these neurons. Subsequently...

journal_title：Brain research

authors： Mandelbrod I,Feldman S,Werman R

更新日期：1983-08-22 00:00:00

abstract：:We assessed the chronological change of the expression of synaptophysin, an integral glycoprotein on the presynaptic vesicles, after a transient cerebral ischemic insult in the rat. The ischemic lesion was consistently localized in the dorsolateral part of the striatum, which was clearly visualized by a depletion of c...

journal_title：Brain research

authors： Korematsu K,Goto S,Nagahiro S,Ushio Y

更新日期：1993-07-09 00:00:00

abstract：:Behavioral studies have shown that emotional facial expressions are detected more rapidly and accurately than are neutral expressions. However, the neural mechanism underlying this efficient detection has remained unclear. To investigate this mechanism, we measured event-related potentials (ERPs) during a visual searc...

journal_title：Brain research

authors： Sawada R,Sato W,Uono S,Kochiyama T,Toichi M

更新日期：2014-04-29 00:00:00

abstract：:The effect of (S)alpha-fluoromethylhistidine (FMH), a specific inhibitor of histamine synthesis from histidine, on ischemic damage was examined in gerbil brain after forebrain ischemia. Two h after subcutaneous FMH injection, the histamine content of the brain was significantly reduced. Neuronal loss in the CA2 region...

journal_title：Brain research

authors： Sugimoto K,Abe K,Lee TH,Sakurai E,Yanai K,Kogure K,Itoyama Y,Watanabe T

更新日期：1994-12-15 00:00:00

abstract：:In the cat, cells of the superior colliculus (SC) and the tectofugal pathways of the visual system are highly selective for the direction of a moving visual stimulus. Deep layer units of SC in addition respond to auditory and somatosensory stimuli, but the proportion of such non-visual cells is usually found to be muc...

journal_title：Brain research

authors： Rauschecker JP,Harris LR

更新日期：1989-06-19 00:00:00

abstract：:The distribution and subcellular localization of AH9 antigen, recognized by a monoclonal antibody AH9, were examined in rat brain. Highest expression was observed in the lamina lucidum of the dentate gyrus of the rat hippocampus. Synaptic subfields of other limbic areas also expressed AH9 antigen at a substantial leve...

journal_title：Brain research

authors： Fukuyama R,Rapoport SI

更新日期：1996-05-06 00:00:00

abstract：:Existing data on the expression of H(4) histamine receptor in the CNS are conflicting and inconclusive. In this report, we present the results of experiments that were conducted in order to elucidate H(4) receptor expression and localization in the brain, spinal cord, and dorsal root ganglia (DRG). Here we show that t...

journal_title：Brain research

authors： Strakhova MI,Nikkel AL,Manelli AM,Hsieh GC,Esbenshade TA,Brioni JD,Bitner RS

更新日期：2009-01-23 00:00:00

abstract：:Neurological problems can develop when blood glucose levels rapidly rise or fall yet there has been little experimentation at a cellular level to assess how neurophysiological change may be induced. Using intracellular recording in the rat neocortical slice preparation, we examined pyramidal neurons of layers II-III a...

journal_title：Brain research

authors： Rosen AS,Andrew RD

更新日期：1991-07-26 00:00:00

abstract：:A comparison was made of the effects of left and right cerebral decortication on cytotoxic activity of natural killer and natural cytotoxic lymphocytes in the mouse. Natural killer cytotoxic activity was significantly reduced after right decortication, whereas left decortication led to a less pronounced, though still ...

journal_title：Brain research

authors： Belluardo N,Mudò G,Cella S,Bindoni M

更新日期：1990-08-06 00:00:00

abstract：:The distribution of fast axonally transported proteins was studied by electron microscope radioautography in ciliary ganglia of chickens treated or not treated with acrylamide. At 3 h after the intracerebral injection of [3H]lysine, the preganglionic axons of the untreated chickens displayed few silver grains, mainly ...

journal_title：Brain research

authors： Chretien M,Patey G,Souyri F,Droz B

更新日期：1981-01-26 00:00:00

abstract：:The adult rat retina was evaluated following surgical lesion and after transplantation of embryonic day 15 (E15) retinal tissue. While a surgical incision caused degeneration and ganglion cell death peripheral to lesion site, the addition of an embryonic retinal implant to the lesion site resulted in a reduction of th...

journal_title：Brain research

authors： Laedtke TW,Turner JE

更新日期：1989-10-23 00:00:00