Abstract:
:Using fMRI, cerebral activations were studied in 24 classically-trained keyboard performers and 12 musically unskilled control subjects. Two groups of musicians were recruited: improvising (n=12) and score-dependent (non-improvising) musicians (n=12). While listening to both familiar and unfamiliar music, subjects either (covertly) appraised the presented music performance or imagined they were playing the music themselves. We hypothesized that improvising musicians would exhibit enhanced efficiency of audiomotor transformation reflected by stronger ventral premotor activation. Statistical Parametric Mapping revealed that, while virtually 'playing along׳ with the music, improvising musicians exhibited activation of a right-hemisphere distribution of cerebral areas including posterior-superior parietal and dorsal premotor cortex. Involvement of these right-hemisphere dorsal stream areas suggests that improvising musicians recruited an amodal spatial processing system subserving pitch-to-space transformations to facilitate their virtual motor performance. Score-dependent musicians recruited a primarily left-hemisphere pattern of motor areas together with the posterior part of the right superior temporal sulcus, suggesting a relationship between aural discrimination and symbolic representation. Activations in bilateral auditory cortex were significantly larger for improvising musicians than for score-dependent musicians, suggesting enhanced top-down effects on aural perception. Our results suggest that learning to play a music instrument primarily from notation predisposes musicians toward aural identification and discrimination, while learning by improvisation involves audio-spatial-motor transformations, not only during performance, but also perception.
journal_name
Brain Resjournal_title
Brain researchauthors
Harris R,de Jong BMdoi
10.1016/j.brainres.2015.06.050subject
Has Abstractpub_date
2015-10-22 00:00:00pages
253-264eissn
0006-8993issn
1872-6240pii
S0006-8993(15)00544-2journal_volume
1624pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract::The dorsal vagal complex of the medulla oblongata is a key centre involved in the regulation of numerous autonomic functions, including cardiovascular control. Adenosine has been implicated as a potential neuromodulator of the baroreceptor reflex, and therefore the current study has investigated the presence and chara...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(94)90327-1
更新日期:1994-07-25 00:00:00
abstract::Slices of the molecular layer of the dentate gyrus of the hippocampal formation were incubated with either [14C]glucose, [14C]pyruvate or 14C glutamine and the efflux of endogenous and radioactive glutamate was monitored under various conditions. After prelabeling with either [14C]glutamine or [14C]glucose elevation o...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(79)90306-8
更新日期:1979-06-08 00:00:00
abstract::We have investigated, in 9 normal subjects, the time course of amplitude changes in the automatic long latency stretch reflex of wrist flexors during the preparatory period as a function of the precued direction of hand movement. Subjects maintained right hand position against a weak force and learned to compensate pr...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(83)91172-1
更新日期:1983-11-28 00:00:00
abstract::We measured expression of the oxytocin gene in the supraoptic nucleus (SON) during pregnancy, parturition and lactation to examine its relationship to states of accumulation or depletion of oxytocin stores and to conditions of strong excitation of oxytocin neurons. The primary transcript (heterogeneous nuclear RNA, hn...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(97)01275-4
更新日期:1998-01-26 00:00:00
abstract::Previous findings from our laboratory demonstrated [125I]angiotensin II (AII) binding to plasma membranes from rat but not gerbil circumventricular organs (CVOs), the presumed location of brain receptors for angiotensin-induced dipsogenicity. Since members of both species drink to intracranially applied AII, a degrada...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(84)90822-9
更新日期:1984-03-12 00:00:00
abstract::Diabetic retinopathy is the leading cause of acquired blindness in working-age individuals. Recent work has revealed that neurodegeneration occurs earlier than vascular insult and that distal optic nerve damage precedes retinal degeneration and vascular insult. Since we have shown that optic nerve degeneration is redu...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2018.07.018
更新日期:2018-12-01 00:00:00
abstract::Bombesin-like immunoreactivity occurs in a dense network of nerve fibres in the rat coeliac-superior mesenteric ganglion. No bombesin immunoreactive cell bodies have been observed in this ganglion. An origin outside the ganglion was therefore assumed for the bombesin immunoreactive fibres. Ligation of the mesenteric n...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(83)90981-2
更新日期:1983-06-13 00:00:00
abstract::The effects of oligemia (moderate ischemia) on the brain need to be explored because of the potential role of subtle microvascular changes in vascular cognitive impairment and dementia. Chronic bilateral common carotid artery occlusion (BCCAO) in adult rats has been used to study effects of oligemia (hypoperfusion) us...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2005.06.018
更新日期:2005-08-02 00:00:00
abstract::Stimulation of cardiac sympathetic afferents evokes excitatory cardiovascular reflexes. However, the exact regions in the brain that integrate these reflexes have not been identified. Expression of c-Fos in the neurons provides a useful marker of the activated neurons. In the present study, we examined the response of...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(01)03259-0
更新日期:2002-01-18 00:00:00
abstract::Levels of somatostatin-like immunoreactivity (SLI) were measured in the rat retina by radioimmunoassay during prenatal and postnatal development. SLI-containing cells were visualized by immunocytochemistry throughout this time period. SLI is present as early as embryonic day 15 (E15) and by E16 at concentrations 10-fo...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0165-3806(87)90209-4
更新日期:1987-08-01 00:00:00
abstract::Previously brain norepinephrine (NE) neurons in the locus coeruleus (LC) have been shown to respond profoundly to external, environmental stimuli and are thought to be involved in behavioral functions such as vigilance, alarm and anxiety reactions to novel and, especially, threatening stimuli. Here we have used electr...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(86)90964-9
更新日期:1986-06-04 00:00:00
abstract::The effect of bilateral lesion of the accessory olfactory bulb (AOB) on the mating-induced enhancement of sexual receptivity was investigated in ovariectomized (OVX) female rats. Lesions of the AOB significantly reduced the lordosis-to-mount (L/M) ratio in mating tests conducted 20 to 50 days after the lesion but L/M ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(94)90902-4
更新日期:1994-04-11 00:00:00
abstract::Discharges of neurons in the midpontine dorsal tegmental field (DTF neurons) were recorded and analyzed during locomotion and were compared with those of reticulospinal neurons (RS neurons) located lateral to the DTF area. The conduction velocity of the descending axon of the DTF neurons was significantly smaller than...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(85)91078-9
更新日期:1985-08-26 00:00:00
abstract::The existence of monosynaptic contacts between primary afferents and motoneurons in the lumbar spinal cord of the turtle Pseudemys scripta elegans was demonstrated by intracellular injections of horseradish peroxidase. Three afferent-motoneuron combinations were satisfactorily labeled and revealed 1, 4 and 6 contacts ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(85)90633-x
更新日期:1985-07-22 00:00:00
abstract::Post-hypoxic myoclonus is a movement disorder characterized by brief, sudden involuntary muscle jerks. Although the mechanism underlying this disorder remains unclear, earlier pharmacological studies indicated that aberrant activity of specific neuronal circuitry in the central nervous system causes this disorder. In ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2005.08.027
更新日期:2005-10-19 00:00:00
abstract::Size matched male green anoles (Anolis carolinensis) were paired in a neutral setting and allowed to engage in aggressive displays. Winners and losers were apparent in each pair within 90min, resulting in stable dominant/subordinate dyads. Androgen receptor (AR) expression was assessed at three time points after the i...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2014.07.028
更新日期:2014-09-25 00:00:00
abstract::Extracellular recordings from 141 rat supraoptic nucleus neurons maintained in vitro in a perfused hypothalamic explant indicated that the excitability of 85% of cells was enhanced by the addition of 10-200 microM norepinephrine (NE) and the alpha-agonist methoxamine (MOXY), but not by isoproterenol, to the perfusion ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(84)90499-2
更新日期:1984-07-30 00:00:00
abstract::This study assessed the contribution of K+ conductances to dopamine (DA)-induced modulation of evoked depolarizing synaptic responses (DPSPs) in neostriatal slices obtained from rats. Intracellular recordings of membrane properties and DPSPs evoked by local electrical stimulation were obtained from cells bathed in sta...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(96)00124-2
更新日期:1996-04-29 00:00:00
abstract::Acute estradiol (E2) can potentiate the excitatory responses of hypothalamic ventromedial nucleus (VMN) neurons to neurotransmitters. To investigate the mechanism(s) underlying the potentiation, the whole-cell patch voltage clamp technique was used to study VMN neurons in hypothalamic slices prepared from female juven...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2006.07.104
更新日期:2006-10-20 00:00:00
abstract::Sardinian alcohol non-preferring (sNP) rats, selected for their low ethanol preference and consumption, carry a point mutation (R100Q) in the gene coding for GABA(A) receptor alpha(6) subunit, which becomes more sensitive to diazepam-evoked GABA currents. We performed binding studies in the cerebellum of normal (RR) a...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(02)04230-0
更新日期:2003-03-28 00:00:00
abstract::Recent researches suggest that autophagic degradation declines with age, and this leads to an accumulation of damage that contributes to age-related cellular dysfunction. Nicotinamide mononucleotide adenylyltransferase 1 (NMNAT1) shows therapeutic potential for cerebral ischemia in young-adult animals. This study inve...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2019.146391
更新日期:2019-11-15 00:00:00
abstract::An increase in medial perforant synaptic strength can be observed for hippocampal slices from rats exposed to environmental enrichment. The expression of enhanced synaptic strength exhibits properties similar to long-term potentiation (LTP), a physiological model of memory storage. Similarities include an increase in ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(96)00707-x
更新日期:1996-10-14 00:00:00
abstract::The postnatal development of cat triceps surae gamma-motoneurones, retrogradely labelled with horseradish peroxidase (HRP), was studied light and electron microscopically. The mean diameter of the cell bodies of the gamma-motoneurones increased by about 25% from birth to the adult stage, which was much less than the i...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0165-3806(87)90251-3
更新日期:1987-12-15 00:00:00
abstract::In order to improve clinical trial design and translation of normobaric oxygen (NBO) treatment of ischemic stroke, NBO treatment parameters need to be better understood. This study investigated NBO treatment efficacy at two different stroke severities and two NBO treatment durations in rats. For the 60-min middle cere...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2016.01.030
更新日期:2016-03-15 00:00:00
abstract::Occlusion of the abdominal aorta proximal to the renal arteries results in an increase in arterial blood pressure, inhibition of forepaw and hindpaw withdrawal to a noxious mechanical stimulus, and inhibition of the tail-flick reflex to noxious heat. Occlusion of the abdominal aorta distal to the renal arteries does n...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(90)90055-g
更新日期:1990-06-11 00:00:00
abstract::The present study examines the brain-level representation and composition of meaning in scalar quantifiers (e.g., some), which have both a semantic meaning (at least one) and a pragmatic meaning (not all). We adopted a picture-sentence verification design to examine event-related potential (ERP) effects of reading inf...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2012.10.042
更新日期:2013-01-15 00:00:00
abstract::Using a monoclonal antibody (192-IgG) directed against the rat beta-nerve growth factor (beta-NGF) receptor the distribution of beta-NGF receptors in the forebrain of the rat has been determined. beta-NGF receptor-containing cells were located in presumed cholinergic cells of the medial septal nucleus, vertical and ho...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(88)91175-4
更新日期:1988-02-02 00:00:00
abstract::Following the implantation of cobalt-gelatine pellets into the frontal cortex, epileptiform spikes in both primary and secondary foci developed and reached a peak between 7-12 days post implantation. Histological examination showed a necrotic lesion with terminal and fibre degeneration in brain areas connected with th...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(75)90288-7
更新日期:1975-07-25 00:00:00
abstract::A push-pull cannula supplied with artificial CSF was implanted in the striatum of anaesthetized rats, and the basal extracellular DA and DOPAC was assayed in the superfusates using HPLC and electrochemical detection. Simultaneously, a carbon fibre electrode was implanted in close proximity of the cannula and the evoke...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(95)00706-v
更新日期:1995-10-09 00:00:00
abstract::Intracellular staining with recording micropipettes filled with a Procion yellow solution was attempted on 11 lateral geniculate neurons of chloralose-anesthetized cats for the purpose of correlating electrophysiologically identified cell types with morphologically identified cell types. Five neurons were successfully...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(78)90058-6
更新日期:1978-01-06 00:00:00