Abstract：
:The effect of bilateral lesion of the accessory olfactory bulb (AOB) on the mating-induced enhancement of sexual receptivity was investigated in ovariectomized (OVX) female rats. Lesions of the AOB significantly reduced the lordosis-to-mount (L/M) ratio in mating tests conducted 20 to 50 days after the lesion but L/M ratios at earlier (10 days) and later (51-90 days) time periods were not affected. The decrease in L/M was accompanied by a reduction in the number of c-fos immunopositive cells in the medial amygdala (mAMYG) and bed nucleus of the stria terminalis (BNST) measured after 3 h of repetitive mating. In the mAMYG, the reduction in c-fos immunoreactivity was correlated to the L/M ratio as well as to the number of intromissions received during the mating tests. The results suggest that information processed from the AOB to the mAMYG and the BNST is important for facilitation of lordosis behavior, and that the mAMYG may integrate information from the AOB with ascending input activated during copulatory behavior to regulate receptivity.
journal_name
Brain Resjournal_title
Brain researchauthors
Dudley CA,Moss RLdoi
10.1016/0006-8993(94)90902-4subject
Has Abstractpub_date
1994-04-11 00:00:00pages
29-37issue
1-2eissn
0006-8993issn
1872-6240pii
0006-8993(94)90902-4journal_volume
642pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract：:Systemic administration of kainic acid in the rat results in the development of a characteristic excitotoxic syndrome, consisting of automatisms (wet dog shakes, WDS), sustained limbic seizures and brain damage. Since kainate increases the release of excitatory amino acid neurotransmitters such as glutamate, this synd...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(94)90227-5
更新日期：1994-08-01 00:00:00
abstract：:Presumptive neurons, immature neurons and degenerating structures were found in the intermediate and deep layers of the superior colliculus of normal cats over the age range 7-45 days postnatal. Electron microscopical analysis revealed these structures to be unexpectedly frequent in the early postnatal period. There w...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0165-3806(84)90013-0
更新日期：1984-05-01 00:00:00
abstract：:To characterize central nervous system changes that occur with anabolic steroid abuse in humans, immunocytochemical localization of androgen receptors in the brains of 10 intact and 10 castrated male rats was conducted after the administration of high levels of androgenic-anabolic steroids (AAS; 14 daily injections of...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)90823-6
更新日期：1993-09-17 00:00:00
abstract：:A comparison of morphological and biochemical characteristics of the D1-type dopamine receptor has been assessed in two experimental tissues, the superior cervical ganglion (SCG) and caudate nucleus of the rat. Correlation of the distribution of this dopaminergic binding site using in vitro autoradiographic localizati...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(87)91294-7
更新日期：1987-09-22 00:00:00
abstract：:Peripheral nerve fascicles are deliberately impaled during microneurography experiments. We have assessed conduction block under these circumstances. First we recorded compound action potentials (CAP) in the sural nerve following stimulation of the sciatic nerve. The insertion of injection and microneurography electro...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)91538-4
更新日期：1993-12-24 00:00:00
abstract：:To investigate whether a task rule carried over from the preceding trial modifies an early portion of the stimulus-locked lateralized readiness potential (sLRP), participants were asked to perform two different flanker tasks that were switched. One task required a left-hand response for a central letter "H" in a five-...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2010.05.050
更新日期：2010-07-30 00:00:00
abstract：:Functionally activated sites usually have multiple specificities where coactivation is induced by inputs with different informational content. Using typical voxel-based functional mapping (univariate analysis), it is possible to show the presence of coactivation; however, it is not possible to distinguish whether coac...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2010.10.020
更新日期：2010-12-17 00:00:00
abstract：:The present study examines the effects of ibotenic acid lesions of the medial amygdala, the bed nucleus of the stria terminalis and the medial preoptic area on the display of paced mating behavior in female rats. Lesions of either the medial amygdala or the bed nucleus of the stria terminalis have no effect on the dis...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2003.10.056
更新日期：2004-02-27 00:00:00
abstract：:Acute forebrain ischemia reduced protein kinase C (PKC) activity in the adult rat cortex, striatum and hippocampus by 60-70% after 20 min ischemia episodes, followed by 48 h of recirculation. Ischemia of 1 min, followed by recirculation, produced a less pronounced but significant decrease in PKC activity. The ischemia...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(91)91094-h
更新日期：1991-02-08 00:00:00
abstract：:To test the hypothesis that functional metabolic deficits observed following surgical brain injury are associated with changes in cognitive performance in rodents, we performed serial imaging studies in parallel with behavioral measures in control animals and in animals with surgical implants. Memory function was asse...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2007.01.134
更新日期：2007-05-04 00:00:00
abstract：:Gulf War Illness (GWI) is a chronic disease that affects the 1991 Gulf War (GW) veterans for which treatment is lacking. It has been hypothesized that drugs used to protect military personnel from chemical attacks and insects during the war: pyridostigmine bromide (PB),N, N-diethyl-m-toluamide (DEET), and permethrin (...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2017.12.030
更新日期：2018-02-15 00:00:00
abstract：:The occurrence of hypoxia-ischemia (HI) during early fetal or neonatal stages of an individual leads to the damaging of immature neurons resulting in behavioral and psychological dysfunctions, such as motor or learning disabilities, cerebral palsy, epilepsy or even death. No effective treatment is currently available ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(02)03094-9
更新日期：2002-09-27 00:00:00
abstract：:In the present study we analyzed the effect of ascorbate (0.8 mM)/Fe2+ (2.5 microM)-induced membrane lipid peroxidation on the levels of intracellular free calcium,[Ca2+]i and on the possible mechanisms involved in the perturbation of intracellular calcium homeostasis during oxidative stress. For this purpose, the inf...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(95)01554-x
更新日期：1996-03-25 00:00:00
abstract：:Postsynaptic potentials were evoked in neostriatal neurons by stimulation of the ipsilateral and contralateral medial agranular frontal cortical field (AGm) in the rat. This cortical region is known to project bilaterally to the dorsal lateral head of the caudate-putamen of rats. Ipsilateral stimulation of AGm should ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)91593-3
更新日期：1986-03-05 00:00:00
abstract：:Behavioral responses to light tactile stimulation of the skin of the head of axolotls were variable in occurrence but were of a constant pattern. Retraction of the eyes and gills followed stimulation of dorsal but not ventral skin. Ventral skin yielded lowering of the head. Touching near the lips caused turning of the...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0165-3806(81)90037-7
更新日期：1981-09-01 00:00:00
abstract：:Cytochrome P45011B1 (11 beta-hydroxylase) was detected in the brain of male rats by in situ hybridization methods. Normal Sprague-Dawley rats were compared to the transgenic strain TGR(mRen2)27, characterized by the expression of the murine Ren-2d renin gene and the development of severe hypertension. Specific ribopro...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(96)00540-9
更新日期：1996-09-09 00:00:00
abstract：:An enriched environment has been shown to improve cognitive, behavioral and histopathological outcome after focal cerebral ischemia and head trauma. The purpose of this study was to determine the effect of an enriched environment on histopathology following global cerebral ischemia. Wistar rats (21 weeks of age) were ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(02)04089-1
更新日期：2003-02-21 00:00:00
abstract：:Glioblastoma is the most common primary brain tumor in adults from which about 15,000 patients die each year in the United States. Despite aggressive surgery, radiotherapy and chemotherapy, median survival remains only 1 year. Here we evaluate growth of primary human brain tumor cells in a defined nutrient culture med...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2007.04.064
更新日期：2007-07-09 00:00:00
abstract：:The origin of descending pathways to thoracic and cervical levels of the spinal cord has been investigated with retrograde tracing techniques in a series of pouch young and adult opossums. The opossum was chosen because it is born in a very immature state, 12-13 days after conception, and has a protracted development ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0165-3806(84)90102-0
更新日期：1984-08-01 00:00:00
abstract：:This study attempted to ascertain whether heatstroke-induced ischemia is associated with augmented striatal glutamate release and can be attenuated by NMDA receptor antagonists. Mean arterial pressure (MAP), striatal cerebral blood flow (CBF), striatal glutamate release and striatal neuronal damage score were assessed...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(98)00282-0
更新日期：1998-06-08 00:00:00
abstract：:Daily changes in tryptophan-5-hydroxylase (TrH) activity have been studied in six different 5-HT-containing cell groups (B3, B4, B5, B6, B7, B8,) in the brain stem of rats maintained in a regular cycle of 12 h of light and 12 h of darkness. Significant circadian alternations of TrH activity were observed in most of th...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(77)90647-3
更新日期：1977-03-04 00:00:00
abstract：:Adult Wistar rats injected with the dopamine receptor agonist apomorphine display different types of motility patterns with respect to oral stereotypes and locomotor activities. It was tested whether phenotypes exhibiting either 'sniffing' or 'non-sniffing' behaviour differed in gene structures of dopamine receptors D...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(01)03136-5
更新日期：2002-02-01 00:00:00
abstract：:The effect of different dose, mode and duration of estradiol administration was examined in the different brain catecholaminergic areas in ovariectomized (OVX) female rats. We determined changes in mRNA levels of tyrosine hydroxylase (TH), rate-limiting enzyme in catecholamine (CA) biosynthesis of GTP cyclohydrolase I...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2004.04.002
更新日期：2004-07-23 00:00:00
abstract：:The non-toxic neuronal binding domain of tetanus toxin (tetanus toxin fragment C, TTC) has been used as a vector to enhance delivery of potentially therapeutic proteins to motor neurons from the periphery following an intramuscular injection. The unique binding and transport properties of this 50-kDa polypeptide sugge...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2004.03.007
更新日期：2004-06-11 00:00:00
abstract：:Endothelin (ET) is a small peptide that activates astrocyte proliferation, regulates proliferation and migration of embryonic neural precursor cells and stimulates glioblastoma growth. We found that in mouse brain, ET and its receptor B (ETRB) were highly expressed in the subependymal zone (SEZ), an adult neurogenic n...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2010.01.056
更新日期：2010-03-19 00:00:00
abstract：:This study investigated the effects of electrical stimulation with theta burst stimulation (eTBS) on seizure suppression. Optimal parameters of eTBS were determined through open-loop stimulation experiments and then implemented in a close-loop seizure control system. For the experiments, 4-aminopyridine (4-AP) was inj...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2014.10.025
更新日期：2014-12-17 00:00:00
abstract：:In the present study, we used a repeated restraint stress animal model to observe the changes in the expression of brain-derived neurotrophic factor (BDNF) and B cell lymphoma protein-2 (Bcl-2) in hippocampal neurons of rats, monitored the time course of the expression over 3 weeks post-stress period, and examined the...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2004.06.089
更新日期：2004-10-29 00:00:00
abstract：:Increases in concentration of brain NO are proposed to initiate and mediate migraine headache. Triggered by focal depolarisation, spreading depression (SD) represents a suitable mechanism for eliciting widespread release of nitric oxide. The current study examines the effect of sumatriptan, a 5-HT(1B/1D) agonist and e...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(00)02400-8
更新日期：2000-07-07 00:00:00
abstract：:Animal models of cerebral infarction are crucial to understanding the mechanisms of neuronal survival following ischemic brain injury and to the development of therapeutic interventions for victims of all types of stroke. Rodents have been used extensively in such research. One rodent model of stroke utilizes either p...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2005.02.021
更新日期：2005-04-25 00:00:00
abstract：:The behavioral and EEG effects of rat and ovine corticotropin releasing factor (r- and o-CRF) were compared. Both peptides were injected intracerebroventricularly into rats through chronically implanted cannulae. At the doses of 0.1 and 1 microgram both peptides activated the EEG and stimulated motor activity. At the ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(87)90413-6
更新日期：1987-04-07 00:00:00
