Embryonic retinal grafts have a beneficial effect on the damaged host retina.

Abstract:

:The adult rat retina was evaluated following surgical lesion and after transplantation of embryonic day 15 (E15) retinal tissue. While a surgical incision caused degeneration and ganglion cell death peripheral to lesion site, the addition of an embryonic retinal implant to the lesion site resulted in a reduction of this degenerative response. In addition, the embryonic graft also exerted a stimulatory effect in the central direction from the lesion site, as increases in layer thicknesses were seen. We speculate that putative diffusable factor(s) may mediate these effects.

journal_name

Brain Res

journal_title

Brain research

authors

Laedtke TW,Turner JE

doi

10.1016/0006-8993(89)90300-4

subject

Has Abstract

pub_date

1989-10-23 00:00:00

pages

61-6

issue

1-2

eissn

0006-8993

issn

1872-6240

pii

0006-8993(89)90300-4

journal_volume

500

pub_type

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