Abstract:
:The adult rat retina was evaluated following surgical lesion and after transplantation of embryonic day 15 (E15) retinal tissue. While a surgical incision caused degeneration and ganglion cell death peripheral to lesion site, the addition of an embryonic retinal implant to the lesion site resulted in a reduction of this degenerative response. In addition, the embryonic graft also exerted a stimulatory effect in the central direction from the lesion site, as increases in layer thicknesses were seen. We speculate that putative diffusable factor(s) may mediate these effects.
journal_name
Brain Resjournal_title
Brain researchauthors
Laedtke TW,Turner JEdoi
10.1016/0006-8993(89)90300-4subject
Has Abstractpub_date
1989-10-23 00:00:00pages
61-6issue
1-2eissn
0006-8993issn
1872-6240pii
0006-8993(89)90300-4journal_volume
500pub_type
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